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Antigen Expression Equipment Supplied In Usa Washington
3 equipment items found
Manufactured by:Universal Cells Inc. based inSeattle, WASHINGTON (USA)
The HLA Class II molecules DP, DQ and DR present peptides to CD4+ T cells and are composed of polymorphic alpha and beta chains. All Class II molecules are expressed from promoters that require the same set of transcription factors. Mutations in the transcription factors RFX5, RFXANK, RFXAP, or CIITA prevent HLA class II expression and cause Bare Lymphocyte Syndrome. Universal Donor Cells can ...
Manufactured by:Universal Cells Inc. based inSeattle, WASHINGTON (USA)
Realizing the potential of pluripotent stem cells requires that the therapeutic cells derived from PSCs be accepted by patients. PSC-derived cells that have not been engineered to avoid allogeneic rejection will be eliminated soon after transplantation unless they are HLA-matched to their recipients, delivered to immune privileged sites, or administered along with potentially dangerous ...
Manufactured by:Aptevo Therapeutics based inSeattle, WASHINGTON (USA)
ALG.APV-527 is a bispecific antibody candidate targeting 4-1BB x 5T4 and is intended for tumor-directed treatment of solid cancers. It was built using Aptevo’s ADAPTIR™ bispecific technology platform and combines binding domains sourced from Alligator Biosciences’ ALLIGATOR-GOLD® human scFv ...