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Targeting Disease Equipment Supplied In Usa
46 equipment items found
by:UNITY Biotechnology based inSouth San Francisco, CALIFORNIA (USA)
UBX1325, a potent Bcl-xL inhibitor, is in clinical development for the treatment of age-related diseases of the eye, including diabetic macular edema (DME), age-related macular degeneration (AMD), and diabetic retinopathy (DR). UBX1325 is designed to selectively eliminate the senescent cells accumulating in diseased blood vessels of the eye. This novel approach ...
by:Mazen Animal Health based inAmes, ALABAMA (USA)
The platform's efficacy is driven by a methodical process including protein design, where subunit antigens are selected to target diseases effectively, followed by the insertion of these genes into the corn genome to maximize antigen expression. The oral vaccine delivery through feed results in a rapid immune response, providing immediate protection for ...
by:DEARGEN Inc. based inDaejeon, SOUTH KOREA
MolEQ designs novel compounds by optimizing multiple properties such as efficacy and toxicity of a lead ...
Manufactured by:Symberix, Inc. based inDurham, NORTH CAROLINA (USA)
Trillions of microorganisms colonize the human body and play a central role in health and disease. Symbiotic drugs target bacteria to improve human health while leaving good microbes ...
Manufactured by:MorphoSys AG based inPlanegg, GERMANY
Peptides are an increasingly important class of drug. As natural ligands to many targets, they can combine agonistic or antagonistic activity with low toxicity risk and can be applied to disease targets, where small molecules or antibody-based drugs cannot be used. However, the number of therapeutic peptide drugs is held back by properties that ...
Manufactured by:CathWorks based inIrvine, CALIFORNIA (USA)
Wire-free and drug-free 3D FFR guidance, practical for every case. Interactive 3D reconstruction of coronary tree, color-coded by FFR value. Highly accurate FFR results for multiple vessels. Angiograms overlaid with QCA and FFR for anatomical context. Interactive vessel sizing tool and 3D QCA for procedural ...
Manufactured by:Novo Nordisk A/S based inBagsværd, DENMARK
Our proprietary GalXC technology leverages a naturally occurring biologic process, ribonucleic acid interference, RNAi, to create therapies that silence disease-causing genes. This platform enables Dicerna to create molecules that can effectively interfere with the RNAi processes that lead to defective or misregulated proteins that cause disease. ...
by:Dyno Therapeutics based inWatertown, MASSACHUSETTS (USA)
Our CapsidMap™ platform uses AI to systematically and rapidly optimize AAV capsids, overcoming the limitations of naturally occurring virus capsids by improving targeting ability, payload size, immune evasion and manufacturability. By building a massive and detailed map of synthetic AAV capsid sequence space, we can quickly navigate the landscape to find enhanced gene therapy vectors with ...
Manufactured by:Suono Bio based inFoxborough, MASSACHUSETTS (USA)
This enables us to “push” virtually any therapeutic class, including temperamental molecules, like nucleic acids, directly into cells with astounding efficacy and accuracy, affecting historically "undruggable" targets. We harness the power of ultrasound-induced cavitation to achieve this delivery and are applying it to creating new treatments for a variety of ...
Manufactured by:Clearside Biomedical based inAlpharetta, GEORGIA (US) (USA)
The suprachoroidal space is a potential space that traverses the circumference of the eye’s posterior region and lies internal to the sclera and external to the choroid. The innermost layer of the choroid, known as Bruch’s membrane, is compact. The outermost border is more a zone of transition, consisting of several lamellae with variable thickness. Because of its proximity to the ...
by:Zymeworks Inc based inVancouver, BRITISH COLUMBIA (CANADA)
with a modular suite of proprietary cytotoxins (cell-killing compounds), stable linkers, and conjugation technologies. A broader window of opportunity. Deliver potent cell-killing compounds specifically to diseased target cells with optimal safety and efficacy. ZymeLink™, a next-generation antibody drug conjugate (ADC) platform, is a suite of proprietary ...
Manufactured by:Plasmend Medical, LLC based inNiwot, COLORADO (USA)
Clinically, Plasmend NTP has been shown to: Kill and distress pre-cancer and cancer cells. Invoke immunological response through the modulation of macrophages and dendritic cells. Disrupt biofilms and eradicate bacteria, spores, viruses, fungi, including multidrug resistant organisms. Promote angiogenesis, tissue regeneration through stimulation of stem cells. ...
Manufactured by:DermBiont, Inc. based inBoston, MASSACHUSETTS (USA)
leverage cutting edge innovation in dermatology and proprietary technology to efficiently develop targeted small molecule therapeutics and novel microbiome-based therapeutics for dermatologic indications that address the root cause of skin diseases. Our in-house discovery platform for microbiome-based therapeutics is enabled by terabytes of DNA sequencing data ...
Manufactured by:Benevolent based inLondon, UNITED KINGDOM
Better target discovery and compound design in Ulcerative Colitis. What is UC?: Ulcerative colitis (UC) is a chronic, lifelong disease that causes inflammation and ulceration of the inner lining of the colon and rectum, accompanied by debilitating symptoms. ...
by:Sirenas based inSan Diego, CALIFORNIA (USA)
The Global Leader in the Discovery of Natural Product Chemistry for Healthcare. Sirenas prides itself on being at the forefront of computational metabolomics for chemical discovery. Our deep experience and historical productivity indicate that these cutting-edge tools, when applied to living systems, can generate the insights necessary to forge new classes of therapeutics and health products. ...
by:DEARGEN Inc. based inDaejeon, SOUTH KOREA
DearDTI presents drug candidates with a good efficacy by predicting the binding affinity, based on information about the compound-protein ...
Manufactured by:NexImmune, Inc. based inGaithersburg, MARYLAND (USA)
The injectable modality (AIM INJ) is an injectable pharmaceutical product of AIM nanoparticles decorated with antigen-specific peptides and co-stimulatory molecules appropriate for the disease being targeted. Based on specific size and bio-distribution characteristics, the AIM™ nanoparticles have the ability to engage antigen-specific T cell populations at ...
Manufactured by:Lumen Bioscience, Inc. based inSeattle, WASHINGTON (USA)
We design and manufacture therapeutics against disease targets that have been inaccessible to the biopharmaceutical industry because of the astonishingly high cost of traditional methods. Now, for the first time, Lumen can make antibodies and other biologics at a cost that allows for daily, high-dose, oral and topical delivery. Our current programs ...
by:Kephera Diagnostics, LLC based inFramingham, MASSACHUSETTS (USA)
At Kephera, we are developing rapid tests for infectious diseases using novel immunochemistry in point-of-care format. Our proprietary assay technology is based on principles of particle interaction combined with a simple device, which together enable rapid detection of specific antibodies or antigens associated with the target pathogen. The broadly enabling ...
Manufactured by:Moderna, Inc. based inCambridge, MASSACHUSETTS (USA)
At Moderna, we are delivering on the promise of mRNA science to create a new generation of transformative medicines for ...