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Ncardia - Atrial Cardiomyocytes
Human-induced pluripotent stem cell (iPSC) derived atrial cardiomyocytes are a powerful tool to improve in vitro investigation of atrial arrhythmias, helping elucidate underlying mechanisms and develop new specific and effective treatments. Ncardia Atrial Cardiomyocytes can be manufactured at the scale needed with high purity and consistency between batches, which ensures minimal variability in large screenings. This cell model is fully characterized by our scientific team and it is amenable for multiple functional assays that will provide an accurate prediction of your compound`s safety and efficacy, increasing the confidence of your therapeutic candidates in early drug discovery.
- Avoid lot-to-lot variability with dedicated, large batch sizes
- Functional and physiologically relevant
- Highly suitable for electrophysiological studies
Ncardia Atrial Cardiomyocytes are characterized by flow cytometry to ensure a high purity of atrial-like cardiomyocytes, assessing double expression of cardiac Troponin T (cTNT) and the transcription factor COUPII (COUP-TFII). They typically present an atrial-like genetic profile as shown by RNA-seq data looking at atrial/ventricular fold expression. Expression levels of RNA-seq data are available upon request.