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30 services found
by:Anresco Laboratories based inSan Francisco, CALIFORNIA (USA)
Cannabinoids are the naturally occurring chemical compounds found in cannabis that work together to produce varying psychoactive and non-psychoactive effects. In combination, they are known to act synergistically to form an ‘entourage effect’, providing benefits beyond what each individually would ordinarily ...
Manufactured by:Proteomics International based inNedlands, Perth, AUSTRALIA
Comprehensive suite of new pre-clinical and clinical testing capabilities: pharmacokinetic (PK), pharmacodynamic (PD), and companion diagnostic (CDx) services. Proteomics International applies its proven expertise and experience in targeted mass spectrometry to the field of PK testing. Mass spectrometry is ideal for the accurate and precise quantitation of target drugs and their break-down ...
Manufactured by:Nexelis based inSeattle, WASHINGTON (USA)
Including Pharmacokinetics and Immunogenicity. Designed to be an extension of your laboratory, Nexelis, a Q² Solutions Company, supports bioanalysis in all phases with agile assay development to validation mindset. Whether we design a custom bioanalytical assay or support a client’s technology transfer, our method development process results in an optimized assay compliant with global ...
by:Bureau Veritas North America, Inc. based inNew York, NEW YORK (USA)
What are APIS and should I Be Concerned about Them? Active pharmaceutical ingredients (APIs) are defined as any substance or a mixture of substances that when used in the production of a drug, becomes an active ingredient in the drug product. Unlike most chemical hazards in the workplace for which health effects upon exposure are incidental, the purpose of an API is to have the maximum biological ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Far-western blot is a molecular biology method based on western blot technology that can be used to detect protein-protein interactions in vitro, especially interactions that do not require the natural structure of the target ...
by:Activation Laboratories Ltd. based inAncaster, ONTARIO (CANADA)
ActLabs Biotech scientists can assist with innovative biomarker assay development and validation. To compliment our range of immunoassays, we also offer LC-MS/MS technology that has enabled us to extend our portfolio to include more biomarkers. In addition, we have invested in the field of multiplexing, using a bead-based suspension and electro-chemiluminescence-based platform ( Luminex Biorad ...
by:SGS M-SCAN Ltd based inWokingham, UNITED KINGDOM
In collaboration with the clinical team, SGS has actively pursued innovative biomarker assay development and validation. To complement our range of immunoassays, we are now offering LC-MS/MS technology that has enabled us to extend our portfolio to include more biomarkers such as steroidal and hormonal substances in the low picogram range. We have also invested in the field of multiplexing, using ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Leukotrienes (LTs) are a group of inflammatory lipid mediators derived from arachidonic acid (AA) via the 5-lipoxygenase (5-LOX) pathway. A characteristic feature of LTs is that they are produced by leukocytes and share a conjugated triene structure. LTs consist of cysteinylleukotrienes (CysLTs) and leukotriene B4 (LTB4). CysLTs contain a cysteine ring, whereas LTB4 is a noncysteine containing ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Sphingolipids are fundamental structural components of cell membranes, forming lipid rafts by combining with other components. Sphingolipids are involved in regulating biological processes such as cell growth, differentiation, and apoptosis. Ceramide is the central hub of the sphingolipid pathway, including sphingomyelin, glucosylceramide, and galactosylceramide, and is mainly divided into ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Diacylglycerol (DAG), also known as diglyceride, consists of two fatty acid chains and a glycerol molecule. It primarily exists in two forms: 1,2-diacylglycerol and 1,3-diacylglycerol. DAG can be synthesized via the phosphatidic acid pathway in the endoplasmic reticulum by the action of phosphatidic acid phosphatase or produced during the lipolysis of triglycerides (TAG) by TAG lipase. DAG is ...
Manufactured by:Cambrex Corporation based inEast Rutherford, NEW JERSEY (USA)
Cambrex has extensive experience in Drug Metabolism and Pharmacokinetic (DMPK), Bioanalytical and Biopharmaceutical Analyses. The Biopharmaceutical Analyses scope supports GMP method development, validation, and routine analysis including but not limited to host cell proteins, host cell DNAs, endotoxins, enzyme kinetics, and even bacteriophage titering assays. The Drug Metabolism and ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Active Pharmaceutical Ingredients (APIs) are substances or mixtures employed in the production of drugs. They have pharmacological effects or directly contribute to diagnosing, treating, mitigating symptoms, controlling, or preventing diseases, in addition to influencing the structure or function of the body. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
mRNA medication is a novel therapeutic method that utilizes messenger RNA (mRNA). mRNA is a sequence of ribotide that encodes for proteins and can express specific proteins through the translation process within cells. The core principle of mRNA medications is to introduce designed mRNA molecules into the patient's body to produce proteins needed for treatment by utilizing the host cell's ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Antibodies bind to various antigens with high affinity and specificity, playing a crucial role in adaptive immune response to infections and can also mediate autoimmune diseases by targeting self-antigens. Antibodies facilitate immunity by inhibiting critical stages of a pathogen's replication cycle, such as receptor binding and cellular entry, activating the complement system, or initiating ...
by:James Hutton Limited based inDundee, UNITED KINGDOM
Our expertise in all aspects of crop science – including breeding, diagnostics, soils, pathogens, genetics and phytochemistry, lends itself to the burgeoning European cannabis and hemp agricultural sector. Our experience of compound and contaminant analyses, including oils, makes us the perfect choice for the analysis of cannabidiol, cannabinoids and CBD ...
by:SGS M-SCAN Ltd based inWokingham, UNITED KINGDOM
With over 25 years of experience and operating out of three GLP compliant laboratories, SGS’s Life Science Services provides pharmacokinetic analysis and bioanalytical services with a dedicated team of specialists. Pharma and biotech companies of all sizes have chosen us as the preferred bioanalytical partner. SGS has the expertise to both develop assays de novo (including immunoassays) and ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Peptides are compounds formed by multiple amino acids linked by peptide bonds and can be prepared via recombinant DNA expression, biological extraction, or chemical synthesis. Peptides represent a unique class of drugs with certain characteristics of small molecule drugs as well as properties of large proteins and other biologics. Most intrinsic signaling molecules are peptide-based, such as ...
Manufactured by:Arthus Biosystems, LLC based inChantilly, VIRGINIA (USA)
SAM analog and antibody: One of the important S-adenosylmethionine (SAM) analogs has a very good thermostability and yet a high hygroscopicity. This analog can also be used as a standard in in intro assays of ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Prostanoids, also known as eicosanoids, are a family of signaling molecules produced and secreted by various types of cells under both normal and pathological conditions. In the human body, these metabolites are excreted into body fluids such as plasma and urine. The precursors of prostanoids are 20-carbon polyunsaturated fatty acids (PUFAs) like arachidonic acid (C20:4), which are esterified in ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Proteolysis targeting chimera (PROTAC) drugs offer a novel approach to disease treatment by leveraging the body's innate protein degradation pathways. In contrast to traditional small-molecule inhibitors, PROTAC drugs promote the degradation of specific proteins rather than directly inhibiting their function, thus mitigating or eliminating their role in disease progression. ...