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Drug Like Molecules Services Available In Iran
18 services found
by:Acellera based inStanmore, UNITED KINGDOM
This protocol simulates the target of interest (GPCR, kinase, ion channel, etc.) in a solution of water and a co-solvent, like benzene or any other fragment-like molecule. During the simulation, the co-solvent molecules interact with the surface of the protein, revealing binding hotspots. These hotspots have been proven to ...
by:Ainnocence Inc. based inSacramento, CALIFORNIA (USA)
Simple : CarbonAI searches over 1.9 billion compounds to create synthesizable drug candidates – based only on target sequence. Precise : CarbonAI accurately identifies the most active and safe compound with a multi-objective optimization ...
Manufactured by:Absolute Antibody Ltd based inRedcar, UNITED KINGDOM
Binding multiple epitopes with a single antibody offers several benefits. For example, one specificity may target individual molecules while another could recruit effector cells or deliver a drug to the target. Other options include dual-target bispecifics which might detect a desired cell type with much higher selectivity than a monospecific antibody. One of Absolute Antibody’s engineering ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
The construction of an antibody-drug conjugate (ADC) is the covalent coupling of a monoclonal antibody and a toxic payload drug via a linker molecule. The ultimate goal for an ADC development project is to deploy the resulted ADC into in vivo systems, both in model animals and eventually human patients, to cure cancer and other diseases utilizing its payload ...
by:Strateos Inc. based inMenlo Park, CALIFORNIA (USA)
Hit optimization is a critical step in drug discovery to funnel into lead optimization. Select the most promising hits and leverage H2L, and automated chemical synthesis workflows for faster experimental screening cycles, decreased duration and hands on time, reducing the overall drug discovery timeline leading to promising preclinical candidates. Rapid turnaround of assay data on new small ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
mall molecule drugs are chemically synthesized active organic compounds with a low molecular weight usually less than 900 daltons which can be made into tablets or capsules that are easily absorbed. As traditional form of medicine, small molecule drugs have always been an important part of drug research and have irreplaceable places. Up to now, small molecule drugs involved in therapeutic use can ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
The construction of an antibody-drug conjugate (ADC) is the covalent coupling of a monoclonal antibody and a toxic payload drug via a linker molecule. The ultimate goal for an ADC development project is to deploy the resulted ADC into in vivo systems, both in model animals and eventually human patients, to cure cancer and other diseases utilizing its payload efficacy. However, prior to in vivo ...
Manufactured by:Ozgene Pty Ltd. based inBentley DC, AUSTRALIA
Knock-in mice have an insertion in a specific locus in order to produce genetically modified mice for customised research purposes. Reporter genes, human genes, related genes from the same organism, or point mutations can be introduced into the protein-coding region of a gene to produce knock-in mice. The difference between the knock-in and knockout approach is that knock-in mouse models are ...
by:Strateos Inc. based inMenlo Park, CALIFORNIA (USA)
Strateos offers a wide range of the shelf assays and supports custom development of biochemical, biophysical and cellular assays using both industry-standard and innovative technologies to support drug discovery projects from hit identification to lead optimization. We also have broad experience in a variety of target classes ranging from GPCRs, kinases, ion channels, nuclear receptors, proteases ...
by:Strateos Inc. based inMenlo Park, CALIFORNIA (USA)
Hit discovery or hit identification in drug development is driven by the need to identify small molecules with desirable activity in a compound screen against a target. Our state-of-the-art fully automated robotic platform is set-up to accelerate your drug discovery process starting with robust, targeted hit identification services. Our system can efficiently run biochemical, phenotypic and ...
Manufactured by:Newcells Biotech Limited based inNewcastle Upon Tyne, UNITED KINGDOM
Cross-species comparison of drug handling with near-physiological kidney transporter model. New drug molecules are usually tested in vivo in two preclinical species to gain a more detailed understanding of how they are transported and eliminated through the kidney and also to mitigate risk of renal toxicity in humans. However, these animal models are not always predictive of human responses. To ...
by:Strateos Inc. based inMenlo Park, CALIFORNIA (USA)
One of the challenges in drug discovery and development is miniaturization. Miniaturization is key to automating small molecule discovery, facilitating higher throughput, increasing reliability and accuracy and reducing costs for screening large compound libraries. We have a solid track record in miniaturizing challenging assays to 384- and 1536-well formats for medium to Ultra-High-Throughput ...
by:Strateos Inc. based inMenlo Park, CALIFORNIA (USA)
High throughput screening (HTS) in drug discovery is critical for drug discovery and is a widely used tool for querying small molecule chemical libraries to determine the structure-activity relationship (SAR) of molecules and helps drive the development of specific and potent bioactive ...
Manufactured by:Exscientia based inOxford, UNITED KINGDOM
Only with continual feedback between experiment and prediction can machine learning models be refined and deliver against complex therapeutic ...
Manufactured by:Nexelis based inSeattle, WASHINGTON (USA)
From Fit-for-Purpose Development to Qualified and Validated Clinical Assays. Nexelis, a Q² Solutions Company, is a leading partner in assay development and technology transfer, with scientific discipline, critical thinking, and agility. Fit-for-purpose assay development on a wide variety of platforms support your small molecule, large molecule, or vaccine program through all phases of ...
by:OracleBio based inGlasgow, UNITED KINGDOM
At OracleBio, we have extensive experience in providing pre-clinical services to support clients in the early stages of the drug discovery pipeline. We understand that our clients need their data quickly, so we work hard to ensure a fast turnaround time, with a team of dedicated image analysis scientists and high-powered computing servers for fast image processing. ...
by:NOVO Engineering based inVista, CALIFORNIA (USA)
Device Types: On-body injectors; Autoinjectors; Pen injectors; Prefilled syringes; Insulin pumps; Microneedle array devices; Smart pills; Electroporation-enabled ...
Manufactured by:Micropore Technologies Ltd. based inRedcar,, UNITED KINGDOM
Commercialisation of sustained release formulations began in the 1970s with PLA & PGA used for surgical implants and sutures. PLGA (Poly (lactic acid-co-glycolic acid)) quickly emerged as the most important biocompatible, non-toxic polymer with numerous applications in drug delivery, tissue engineering, medical and surgical ...