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Phenotyping Services Available In Iran
25 services found
by:Rady Children`s Institute for Genomic Medicine based inSan Diego, CALIFORNIA (USA)
We provide a quick turnaround, offering actionable results to guide Rapid Precision Medicine™ and improve patient outcomes. Phenotype-Driven Results: Rapid, robust phenotype-driven results are delivered to inform medical management. Actionable Next Steps: We expedite disease-specific molecular diagnoses in time to make a clinical difference. Expert ...
by:OracleBio based inGlasgow, UNITED KINGDOM
Adding value to Immuno-Oncology studies with Quantitative Digital Pathology. Quantitative Digital Pathology provides deep insights into the tumor microenvironment (TME), a knowledge which is crucial for understanding the mechanism of action of new oncology immunotherapies or for investigating new biomarkers. ...
Manufactured by:Creative Biogene-Mitochondrial Research based inNY, NEW YORK (USA)
Mitochondrial dysfunction is rapidly developing as a key pathological feature of early and persistent lung disease. In particular, mitochondria are emerging as central to the pathological processes and clinical phenotypes associated with a range of lung diseases. Creative Biogene provides a comprehensive range of services and products to assist researchers in lung-disease-related ...
Manufactured by:vivoVerse Inc. based inAustin, TEXAS (USA)
The vivoChip® enables the use of C. elegans for high-content, multi-parametric analysis of neurodegeneration phenotypes from high-resolution fluorescence images of neurons. To demonstrate our unique capabilities, we studied dendritic neurodegeneration of dopaminergic neurons in C. elegans induced by a well-accepted neurotoxicant, MPP+, showing dose-dependent increase in ...
by:InVivo Biosystems based inEugene, OREGON (USA)
They allow researchers to study the effects of the absence of a particular gene, protein segment, amino acid, or regulatory element, thereby enabling the researcher to determine their function. Gene knockouts are a commonly used tool for biologists to understand gene function. Examination of phenotypes when the gene is deleted can reveal insights into what role that gene plays in ...
Manufactured by:Curi Bio based inSeattle, WASHINGTON (USA)
Curi Bio has a repository of iPSC’s for disease modeling and proprietary technologies for differentiating these cells into myoblasts and cardiomyocytes. Curi has developed in vitro 3D disease models for multiple disease phenotypes. In addition, Curi has the capability of generating new gene-edited iPSC models in ...
by:Strateos Inc. based inMenlo Park, CALIFORNIA (USA)
Our state-of-the-art fully automated robotic platform is set-up to accelerate your drug discovery process starting with robust, targeted hit identification services. Our system can efficiently run biochemical, phenotypic and cellular HTS assays in 384- or 1536-well ...
Manufactured by:Ozgene Pty Ltd. based inBentley DC, AUSTRALIA
These mouse models allow researchers to gain insight into how the loss of the gene affects physiology, behavior and disease development. Observing the characteristics of a knockout phenotype can also help researchers understand human gene expression and genetic ...
Manufactured by:Newcells Biotech Limited based inNewcastle Upon Tyne, UNITED KINGDOM
Activated fibroblasts differentiate into myofibroblasts, a process known as fibroblast-to-myofibroblast transition (FMT). This persistent myofibroblast phenotype leads to an increased synthesis of extracellular matrix proteins, and their deposition within the lung parenchyma, causing progressive scarring, increased lung stiffness and a loss in lung function. ...
Manufactured by:RoosterBio, Inc. based inFrederick, MARYLAND (USA)
As a raw material in emerging cell, gene, and exosome based therapies, understanding the key quality attributes of your hMSC, such as phenotype, function, and growth kinetics are vital to understanding expansion and therapeutic potential. At RoosterBio Inc., we have years of experience in hMSC isolation, manufacturing, and characterization. Leverage this expertise within your ...
Manufactured by:Newcells Biotech Limited based inNewcastle Upon Tyne, UNITED KINGDOM
Both models are iPSC derived allowing gene-edited lines to be engineered using CRISPR/Cas9 for direct comparison between WT and mutant phenotypes after differentiation. Targeted mutations can model retinopathies, more specifically monogenic inherited retinopathies such as retinitis pigmentosa (RP), Stargardt disease, Usher’s syndrome and Leber congenital ...
Manufactured by:ProImmune Ltd. based inOxford, UNITED KINGDOM
Blood collection, shipping and processing is often the first point of failure for cell based immunology assays, such as ELISpot, flow cytometric phenotyping and functional cell based assays. When these assays are planned as part of multi-center clinical trials, setting up processes for collecting processing, shipping, preserving blood incorrectly can have catastrophic ...
Manufactured by:Exscientia based inOxford, UNITED KINGDOM
Drug design is engineering at the molecular scale. Every position of every atom and every bond determines the future success of a ...
by:Strateos Inc. based inMenlo Park, CALIFORNIA (USA)
Strateos offers a wide range of the shelf assays and supports custom development of biochemical, biophysical and cellular assays using both industry-standard and innovative technologies to support drug discovery projects from hit identification to lead optimization. We also have broad experience in a variety of target classes ranging from GPCRs, kinases, ion channels, nuclear receptors, proteases ...
Manufactured by:Ozgene Pty Ltd. based inBentley DC, AUSTRALIA
The targeted transgenic mouse approach uses gene targeting by means of homologous recombination in embryonic stem (ES) cells. The transgene cDNA is knocked into a ‘safe habor’ locus in the mouse genome to generate transgenic mice with a predictable expression pattern without disturbing endogenous gene activity. Safe harbor loci have been utilised in the mouse to investigate gene ...
Manufactured by:Mimetas B.V. based inLeiden, NETHERLANDS
Capture and understand human disease biology in vitro. The key to unlocking effective therapies for the unsolved diseases of our times is a deep understanding of human disease biology. To this end, MIMETAS aims to capture the essence of diseases in fit-for-purpose in vitro models. We are fully committed to reducing human disease complexity into functional and screenable ...
by:Indica Labs Inc. based inAlbuquerque, NEW MEXICO (USA)
Leveraging our own image analysis and image management solutions, HALO, HALO AI and HALO Link, as well as the expertise of our PHARMA SERVICES and algorithm development teams, we offer a wide range of analysis services to pharmaceutical, contract research organizations and research institutes around the world. Whether you require an end-to-end solution or à la carte analysis services, we ...
by:Revvity Gene Delivery (formerly SIRION Biotech) based inHamburg, GERMANY
In the discovery of oncology therapeutics, Antibody-drug conjugates (ADCs) are rapidly gaining momentum, with hundreds of candidates advancing through clinical development. Whether your priority lies in assessing the epitope binding of your construct, evaluating the cytotoxic potency of the payload, or scrutinizing the efficacy of the linker in cleaving, each facet demands meticulous ...
Manufactured by:Catalent, Inc based inSomerset, NEW JERSEY (USA)
At Catalent, our methodologies work toward reducing the overall costs and time it takes to get your product to the clinic. With decades of experience in analytical development, we understand our clients’ needs, the current regulatory environment, and have a history of the development and qualification of analytical methods. We operate with a forward-looking methodology by deploying robust ...
by:Champions Oncology, Inc. based inHackensack, NEW JERSEY (USA)
Champions Oncology's ex vivo AML co-culture platform for Immuno-Oncology therapeutic testing. Champions Oncology has launched an innovative new platform enabling Acute Myeloid Leukemia (AML) researchers the ability to better understand their therapeutic mechanism of action. The Autologous AML Platform is an ex vivo co-culture assay developed and optimized to interrogate the responses of your ...