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Drug Molecule Services Available In Israel
33 services found
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
The Alfa Chemistry platform integrates predictive methods with various computational techniques to accelerate drug discovery. Our iterative process is designed to accelerate evaluation and optimization of chemical matter in silico ahead of synthesis and assay. The most promising compounds emerging from each round of experimental project chemistry are then further optimized through additional ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
mall molecule drugs are chemically synthesized active organic compounds with a low molecular weight usually less than 900 daltons which can be made into tablets or capsules that are easily absorbed. As traditional form of medicine, small molecule drugs have always been an important part of drug research and have ...
by:Ainnocence Inc. based inSacramento, CALIFORNIA (USA)
Simple : CarbonAI searches over 1.9 billion compounds to create synthesizable drug candidates – based only on target sequence. Precise : CarbonAI accurately identifies the most active and safe compound with a multi-objective optimization ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
One-Stop Solution for Small Molecule Drug Formulation: Small molecule drugs are chemically synthesized small molecules of active substances. Small molecule components can be made into tablets or capsules that are easily absorbed by the body. CD Formulation has extensive research experience in ...
by:Strateos Inc. based inMenlo Park, CALIFORNIA (USA)
Hit optimization is a critical step in drug discovery to funnel into lead optimization. Select the most promising hits and leverage H2L, and automated chemical synthesis workflows for faster experimental screening cycles, decreased duration and hands on time, reducing the overall drug discovery timeline leading to promising preclinical candidates. Rapid ...
by:Strateos Inc. based inMenlo Park, CALIFORNIA (USA)
Strateos offers a wide range of the shelf assays and supports custom development of biochemical, biophysical and cellular assays using both industry-standard and innovative technologies to support drug discovery projects from hit identification to lead optimization. We also have broad experience in a variety of target classes ranging from GPCRs, kinases, ion channels, nuclear receptors, proteases ...
by:Strateos Inc. based inMenlo Park, CALIFORNIA (USA)
Hit discovery or hit identification in drug development is driven by the need to identify small molecules with desirable activity in a compound screen against a target. Our state-of-the-art fully automated robotic platform is set-up to accelerate your drug discovery process starting with robust, targeted hit identification services. ...
by:Strateos Inc. based inMenlo Park, CALIFORNIA (USA)
High throughput screening (HTS) in drug discovery is critical for drug discovery and is a widely used tool for querying small molecule chemical libraries to determine the structure-activity relationship (SAR) of molecules and helps drive the development of specific and potent bioactive ...
by:Strateos Inc. based inMenlo Park, CALIFORNIA (USA)
One of the challenges in drug discovery and development is miniaturization. Miniaturization is key to automating small molecule discovery, facilitating higher throughput, increasing reliability and accuracy and reducing costs for screening large compound libraries. We have a solid track record in miniaturizing challenging assays to 384- and 1536-well formats for ...
by:Patheon Inc. based inDurham, NORTH CAROLINA (USA)
Establishing the best synthetic route for your molecule is the basis for a reliable supply throughout the product’s life cycle. During route scouting, the following considerations are important when selecting the optimal pathway: Safety, Efficiency, purity and costs, Ease of optimization and scale up, IP review, Security of supply of raw materials, Impact on waste and the ...
by:Patheon Inc. based inDurham, NORTH CAROLINA (USA)
Comprehensive upstream process development capabilities, including cell line development, and a commitment to innovation, quality and service, make us the ideal partner for the process development of your mammalian cell culture projects. Our expertise spans multiple commercial cell lines, including CHO (Chinese Hamster Ovary), as well as cGMP cell ...
by:Patheon Inc. based inDurham, NORTH CAROLINA (USA)
Broad experience and access to the latest technological capabilities are essential for today’s increasingly complex API development and manufacturing. By partnering with Thermo Fisher Scientific, you’ll work directly with scientists with deep chemistry knowledge and many years of experience in successfully supporting early and later phase clinical development programs. Our experts ...
by:Patheon Inc. based inDurham, NORTH CAROLINA (USA)
Repeatable, High Quality and Robust Process Design; We offer an in-depth understanding of reaction profiles and the quality and physical form of starting materials, intermediates and the final product are critical components of API (active pharmaceutical ingredient) development. To support route scouting and process development activities and accelerate your clinical programs, we provide a ...
by:Patheon Inc. based inDurham, NORTH CAROLINA (USA)
At Thermo Fisher Scientific, our people pride themselves on solving your API development challenges. Our objective is to help speed your molecule through early phase trials and prepare you for commercial success, faster. Whether you start working with us in early phase or late, we draw on years of experience and deep expertise to achieve industry-leading performance. Whether you need small ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
Preparation of Nano-vesicles for Encapsulating Protein Drugs: CD Formulation can customize the vesicles that encapsulate protein drug molecules to avoid the technical problems of drug rupture and leakage during in vivo delivery. Our technical team will perform a full range of analytical tests to ensure that the product meets your ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
Under the influence of various environmental factors (such as temperature, humidity, and light), the stability of active pharmaceutical ingredients (API) or the stability of pharmaceutical products is evaluated. This is helpful to study the internal stability of candidate drug molecules and obtain useful information, it is important to improve the integrity of ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
Liposomes are a novel drug delivery system; they are bimolecular vesicle structures that form spontaneously when phospholipids are dispersed in water. Liposomes vary in size, composition and charge and serve as carriers for a wide range of drug molecules, such as chemotherapeutic agents, anti-microbial and viral drugs, ...
Manufactured by:Newcells Biotech Limited based inNewcastle Upon Tyne, UNITED KINGDOM
Cross-species comparison of drug handling with near-physiological kidney transporter model. New drug molecules are usually tested in vivo in two preclinical species to gain a more detailed understanding of how they are transported and eliminated through the kidney and also to mitigate risk of renal toxicity in humans. ...
by:Acellera based inStanmore, UNITED KINGDOM
This protocol simulates the target of interest (GPCR, kinase, ion channel, etc.) in a solution of water and a co-solvent, like benzene or any other fragment-like molecule. During the simulation, the co-solvent molecules interact with the surface of the protein, revealing binding hotspots. These hotspots have been proven to correlate very well with actual pockets. ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
Microsphere Development: Among the many existing extended release formulations, microspheres have unique advantages such as gradual release of the drug by degradation of the microspheres after administration, avoidance of blood concentration peaks and valleys, reduction of the dose during the therapeutic cycle, and improvement of the bioavailability of the drug ...