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Toxicology Services Available In Italy
35 services found
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
A successful ADC should be chemically and physiologically stable in blood stream, exert similar antigen binding pattern compared with the unconjugated antibody, and exhibit desired payload toxicological effects once internalized. ...
by:IDEXX BioAnalytics based inWestbrook, MAINE (USA)
In the nonstop race to develop lifesaving treatments, accuracy and speed are critical. They are the engines that propel research forward. IDEXX BioAnalytics Preclinical Testing Services is your research partner, supporting your work across clinical laboratory, anatomic laboratory, DABT and ACVP board-certified pathology, and small molecule ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Lead optimization is a complex and iterative process for identifying an improved drug lead with the goal of progressing to a preclinical candidate by altering the chemical structure of a confirmed hit. A diversity of properties such as target’s specificity, selectivity, pharmacodynamics, pharmacokinetics and toxicological properties are improved by modifying the chemical ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Immortalized cell lines and services are of ever-increasing importance in various aspects of biomedicine, toxicology and biotechnology. The cells can be used as model systems in phenotypic and drug screening, high content analysis, target identification, drug development, toxicology testing, gene editing studies, reporter assays. Besides, the immortalized cells ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Immortalized cell lines and services are of ever-increasing importance in various aspects of biomedicine, toxicology and biotechnology. The cells can be used as model systems in phenotypic and drug screening, high content analysis, target identification, drug development, toxicology testing, gene editing studies, reporter assays. Besides, the immortalized cells ...
Manufactured by:Puracyp based inCarlsbad, CALIFORNIA (USA)
Puracyp’s cells contain the promoter/enhancer of these three P450 enzymes in addition to either CAR, AhR, or PXR. Panel screens are also useful for examining species differences in P450 induction and for toxicology studies using orthologs of human nuclear receptors. An example of results obtained in human cell lines utilizing our panel screen for PXR, AhR and CAR are shown ...
by:Envigo based inCambridgeshire, UNITED KINGDOM
It is typically the first human exposure to a New Chemical Entity (NCE) and takes place in a controlled clinical setting. To be granted permission by the regulatory bodies to perform such a study, a comprehensive package of toxicology data, demonstrating safety at many times the human dose in animals, must be submitted. Damage at the gene or chromosomal level can be investigated ...
by:PharmaLex GMBH based inFriedrichsdorf, GERMANY
Going far beyond basic project management, the Integrated Product Development program at PharmaLex represents a partnership between you and our team. Our experts actively contribute to your product’s path to success by integrating nonclinical/clinical, toxicological and crucial biostatistical support with Chemistry, Manufacturing and Controls (CMC) services, regulatory ...
by:North American Science Associates Inc.(NAMSA ) based inNorthwood, OHIO (USA)
NAMSA’s balance of trusted advisors and proven process lets us support clients across the entire medical device product development spectrum.Non-clinical studies are used to select prototypes and provide an understanding of device performance in a specific application. When it comes to non-clinical testing, you can rely on our safety evaluation studies (in vitro and in vivo ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Zebrafish have become the third largest vertebrate model organism after mouse and rat, and have been widely used in many fields such as developmental biology, genetics, basic medicine, pharmacology, toxicology, drug research and development, and ecological environment evaluation. Creative Biolabs provides a one-stop service platform for zebrafish gene knockout/knock-in and ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
Solubility and bioavailability issues run through drug metabolism and pharmacokinetic evaluation of candidate compounds, preclinical prescription development, and commercial formulation development. From the toxicological evaluation stage, CD Formulation has a perfect drug metabolism and pharmacokinetic support system, each experiment only consumes milligram-level API, which can ...
Manufactured by:Neuron Bio based inGranada, SPAIN
The Diagnostic division develops tools and biomarkers for the diagnosis of diseases of the Central Nervous System, as in the case of Alzheimer’s. The Services Division offers a wide range of R&D services in the fields of biomedicine, toxicology and agri-food. Neuron Bio offers preclinical R&D services for the biomedicine, toxicological and ...
Manufactured by:Novodiax, Inc. based inHayward, CALIFORNIA (USA)
Use the Novodiax polymerized horseradish peroxidase (polyHRP) signal amplification technology (ihcDirect) and conjugate it directly to your humanized antibody-of-choice to enable rapid, sensitive IHC testing. Jumpstart your early humanized antibody-to-human tissue testing or ADME/toxicology studies to fail candidates ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
In vitro Skin Models (Human Skin Equivalent, FTSK, HSE) used under defined test conditions offer several advantages: i) since most models are composed of primary human cells, inter-species extrapolation is avoided; ii) in contrast to human skin specimens, repeated application of formulations can be performed for at least several weeks; iii) work with the ready to use tissue models do not require ...
Manufactured by:Werfen based inL`Hospitalet de Llobregat, SPAIN
We offer easy-to-use clinical laboratory instrumentation and reagents for chemistry and pharma-toxicology labs. Our unique solutions are used to diagnose conditions such as diabetes as well as to identify drug ...
Manufactured by:ExcellGene SA based inMonthey, SWITZERLAND
Have you been limited a lack of tox material to properly design your pre-clinical toxicology studies in animals? We will help you plan experiments without the worry of running short. We can deliver up to 500 grams of drug substance from a single batch, in 8 months or less. Our scientific foundation is built on expert knowledge, dependable quality, and timely delivery. ...
by:Andelyn Biosciences based inColumbus, OHIO (USA)
Andelyn Biosciences has more than 20 years of experience in cell and gene therapy manufacturing. We possess the capability and capacity to manufacture batches of plasmids in any size depending on client specifications – from small trials to clinical-scale plasmid ...
by:Ekotoxikologicke Centrum Bratislava s.r.o. based inBratislava, SLOVAKIA
The cosmetic product safety report shall, as a minimum, contain the ...
by:Emmace Consulting AB based inLund, SWEDEN
Testing and determination of Particulate Matter (PM) and Volatile Organic Substances (VOS) according to ISO 18562-2 and ISO ...
Manufactured by:Chanelle Pharma Group based inCo Galway,, IRELAND
At Chanelle, our in-house research and development capabilities are the cornerstone of our operations and continued growth. While we are a generic medicines provider, our commitment to innovation is comparable to brand leaders in the ...