Show results for
Refine by
Creative Biogene Dna Target Services Available In Lesotho
1 services found
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
dCas9 can be fused with a gene repressor protein, the KRAB protein, to form a complex CRISPRi (CRISPR interference) that inhibits gene expression. dCas9-KRAB targeting to the promoter region causes steric hindrance that halts transcript elongation by RNA polymerase, resulting in the target gene being repressed. CRISPR-based gene interference provides an efficient ...