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Biopharmaceutical Biotechnology Services
34 services found
by:Andelyn Biosciences based inColumbus, OHIO (USA)
Andelyn Biosciences provides clients with a broad range of viral vector manufacturing platforms and solutions, including AAV and Lentiviral adherent and suspension systems along with plasmid manufacturing. We support our clients throughout every step of cGMP manufacturing – from pre-clinical trials of gene-modified products and cell therapies to commercial ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
High-throughput methods in metabolomics research generate extensive data on metabolite analysis, requiring bioinformatics methods for processing. Bioinformatics analysts at BGI (Beijing Genomics Institute) can deeply explore and comprehensively analyze metabolomics data from raw mass spectrometry data by performing peak alignment, retention time correction, and peak area extraction. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
MtoZ Biolabs offers meat biomarkers analysis service using UPLC/TripleQuad5500, with high accuracy, specificity, and sensitivity. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Gangliosides are a large class of complex lipids that are abundant in the neuronal cell membranes in the brain. These molecules consist of sphingolipids with one or more sialic acids attached to the sugar chain. As structural components of cell membranes, gangliosides have their two hydrocarbon chains embedded in the plasma membrane, while the oligosaccharides are located on the cell surface, ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
MtoZ Biolabs provides bile acids analysis service using UPLC/TripleQuad5500, which can quantitatively analyze over 90 kinds of bile ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Far-western blot is a molecular biology method based on western blot technology that can be used to detect protein-protein interactions in vitro, especially interactions that do not require the natural structure of the target ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Sphingolipids are fundamental structural components of cell membranes, forming lipid rafts by combining with other components. Sphingolipids are involved in regulating biological processes such as cell growth, differentiation, and apoptosis. Ceramide is the central hub of the sphingolipid pathway, including sphingomyelin, glucosylceramide, and galactosylceramide, and is mainly divided into ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
ATP metabolism involves several key small molecules, including adenosine triphosphate (ATP), adenosine diphosphate (ADP), adenosine monophosphate (AMP), oxidized nicotinamide adenine dinucleotide (NAD+), reduced nicotinamide adenine dinucleotide (NADH), coenzyme A (CoA), acetyl coenzyme A (acetyl-CoA), and inorganic phosphate (Pi). ATP is the primary unit of energy transfer within cells, crucial ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Polyprenols are long-chain isoprenoid alcohols. The general formula for polyprenols is H-(C5H8)n-OH, where n refers to the number of isoprene units. Polyprenols are classified into three types: all-trans (solanesol-type), two-trans (Solanesol-type) and poly-cis (Betulaprenol-type), and three-trans and poly-cis (Ficaprenol-type). Despite their low content, polyprenols are natural bioregulators ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Polyunsaturated fatty acids (PUFAs) are primarily classified into ω-3 and ω-6 fatty acids. The difference between these two fatty acids lies in the position of the first double bond from the methyl end of the fatty acid chain. ω-6 fatty acids have a carbon-carbon double bond at the n-6 ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Antibody drug developability analysis (drugability analysis) is a key strategy used to evaluate the development prospect of candidate antibody drug. This analysis is based on a comprehensive evaluation of multiple aspects of the candidate antibody, including biological activity, pharmacology, pharmacokinetics, safety, and preparation feasibility. Through systematic developability analysis, ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Glycosylation modifications increase the complexity of protein molecular structure and the diversity of functions, not only affecting protein folding, structure, transportation, localization, and biological activity but also regulating various physiological processes such as cell growth, division, differentiation, recognition, and adhesion through specific recognition between sugars and proteins. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Metabolic flux analysis (MFA) is a critical technique for examining the production and consumption rates of metabolites in biological systems. In systems metabolic engineering, MFA helps understand cell physiology under specific conditions and predict metabolic capacities of cells following genetic or environmental changes. MFA is also used to elucidate cellular mechanisms. By using stable ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
KEGG (Kyoto Encyclopedia of Genes and Genomes) database is a database used for systematic analysis of metabolic pathways and functions of gene products in cells. KEGG helps to study genes and its expression information as a whole network. KEGG integrates data from genomes, chemical molecules, and biochemical systems, including metabolic pathways (PATHWAY), drugs (DRUG), diseases (DISEASE), gene ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Leukotrienes (LTs) are a group of inflammatory lipid mediators derived from arachidonic acid (AA) via the 5-lipoxygenase (5-LOX) pathway. A characteristic feature of LTs is that they are produced by leukocytes and share a conjugated triene structure. LTs consist of cysteinylleukotrienes (CysLTs) and leukotriene B4 (LTB4). CysLTs contain a cysteine ring, whereas LTB4 is a noncysteine containing ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Carbon metabolism analysis in MtoZ Biolabs encompasses both one carbon metabolism and central carbon metabolism. The metabolism of certain amino acids can produce groups containing a carbon, known as one carbon unit (C1 unit). These groups can participate in biosynthesis upon transfer. The metabolic processes involving the production and transfer of C1 unit are referred to as one carbon ...
by:ENEA-Italian National Agency for New Technology, Energy and Sustainable Economic Development based inRome, ITALY
ENEA carries out research and innovation activities and provides advanced services on ionizing and non-ionizing radiation. ENEA also develops products, processes and methodologies aimed at understanding the harmful effects and mechanisms of action of noxious chemical and physical agents. This scientific and technical knowledge allows coping with radioprotection and health technologies problems, ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Urine contains a vast array of chemicals, including microbial metabolites and mammalian metabolic products. Drugs, pollutants, and industrial chemicals may also be present in urine. Since urine lacks homeostatic regulation, it can reflect metabolic disturbances, providing insights into systemic changes in response to physiological challenges or disease ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
NAD metabolism-related small molecules include oxidized nicotinamide adenine dinucleotide (NAD+), reduced nicotinamide adenine dinucleotide (NADH), oxidized nicotinamide adenine dinucleotide phosphate (NADP+), reduced nicotinamide adenine dinucleotide phosphate (NADPH), nicotinamide mononucleotide (NMN), nicotinamide (NAM), nicotinamide riboside (NaR), and adenosine triphosphate (ATP). NAD+, also ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Small molecules predominantly modulate the activity of their protein targets. The majority of approved small molecule inhibitors target intracellular kinases, which regulate cell signaling by transferring phosphate groups to target proteins. Contemporary research extensively focuses on targets implicated in protein-protein interactions, cancer metabolism, and immune ...