Refine by
Drug Efficacy Services
15 services found
Manufactured by:Advanced Cell Diagnostics, Inc. based inNewark, CALIFORNIA (USA)
There is growing interest in RNA-based biomarkers and measuring RNA expression holds great promise for stratifying patients based on drug response, drug efficacy and risk of side effects. RNAscope in situ hybridization enables molecular detection in a morphological context. It provides the cellular resolution required to evaluate tissue ...
Manufactured by:Invicro, LLC based inNeedham, MASSACHUSETTS (USA)
We focus on studies containing imaging and pathology-based endpoints requiring robust, independent assessments to ascertain drug efficacy. Our imaging core lab and CAP/CLIA lab-based pathology services solutions support various therapeutic areas including oncology, immuno-oncology, neurology (CNS), cardiovascular, musculoskeletal and gastrointestinal. Our ...
by:Burning Rock Biotech Limited based inGuangzhou, CHINA
Burning Rock utilizes our own proprietary large-scale genomic dataset based on personalized analyses of Chinese cancer patients*, ntegrates the experience from multi-dimensional clinical/scientific research and published data, to provide a one-stop cancer genomic data solution for biopharma partners, aiming to speed up precision drug development and reduce the risks. Burning Rock ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Aggregation or fragmentation of protein molecules primarily causes variations in molecular size, impacting their biological activity, stability, and their efficacy and safety as pharmaceuticals. In the development and production of biopharmaceuticals, even slight variations in molecular size can reduce drug efficacy or pose safety risks. Thus, ...
by:Envigo based inCambridgeshire, UNITED KINGDOM
There are many qualities that differentiate a chemical from a drug. From therapeutic efficacy to it"s first-pass metabolism in man, there are a variety of characteristics that make it more, or less, likely that a chemical will make an effective and safe therapeutic. At Huntingdon Life Sciences, we recognise that it can be vitally important to understand as many ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
The discovery of active compounds with novel skelecton is a great challenge for modern medicinal chemistry. It can not only improve the efficacy and drug-like properties of molecules, but also help pharmaceutical companies break patent barriers and build core competitiveness. Skeleton transition is a commonly used strategy for exploring novel skeleton, which ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
Antibacterial, anti-inflammatory, and antiviral drugs are commonly used clinically. However, with the spread and evolution of drug resistance, the efficacy of these drugs, especially antibacterial and antiviral drugs, is declining. At present, there is no effective means to deal with the problem of ...
by:American Council of Independent Laboratories (ACIL) based inWashington, DISTRICT OF COLUMBIA (USA)
ACIL members in its Food Sciences Section (FSS), perform microbiological, chemical and physical services to characterize composition, purity, residue content and contamination in the areas of food, pharmaceuticals, cosmetics, and related manufacturing industries. Testing and research the safety and/or efficacy of drugs, cosmetics, food additives, medical devices, ...
Manufactured by:Firalis Group based inHuningue, FRANCE
The successful implementation of a biomarker endpoint is highly dependent on the availability of assays and on reliable measurements of markers in biological samples. While a large number of assays are on the market, scientists often have an urgent need for assays meeting specific ...
Manufactured by:Charles River based inHollister, CALIFORNIA (USA)
Our scientific and regulatory staff work with clients to develop and execute individual studies or customized testing programs to ensure that drug safety and efficacy assessments are conducted in the most efficient ...
Manufactured by:MedGenome Inc. based inCounty of New Castle, DELAWARE (USA)
Profiling the Tumor Microenvironment: Using a genomics based approach to analyze the tumor microenvironment can provide unique insights beyond IHC and FACS methods. OncoPeptTUME deeply interrogates RNA-Seq data sets to produce high resolution mapping of the tumor microenvironment using proprietary cell type specific gene expression signatures. OncoPeptTUME provides a critical assessment of the ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Creative Bioarray provides various in vitro ADME/PK services including high-throughput ADME screening, in vitro metabolism, in vitro permeability and transporter assays. ADME is short for "absorption, distribution, metabolism, and excretion". The four properties determine the drug level within a body, the drug exposure to tissues, and the metabolic process of a compound, which can help predict ...
Manufactured by:Micropore Technologies Ltd. based inRedcar,, UNITED KINGDOM
Commercialisation of sustained release formulations began in the 1970s with PLA & PGA used for surgical implants and sutures. PLGA (Poly (lactic acid-co-glycolic acid)) quickly emerged as the most important biocompatible, non-toxic polymer with numerous applications in drug delivery, tissue engineering, medical and surgical ...
Manufactured by:Altis Biosystems based inDurham, NORTH CAROLINA (USA)
Accurate biological screening based on real human intestinal tissue, with a standardized workflow for reliable and reproducible data, RepliGut represents ?the next generation for in vitro testing with faster actionable data. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
MtoZ Biolabs offers highly sensitive and accurate Antibody-Drug Conjugate (ADC) Analysis service based on high-throughput liquid chromatography and high-resolution mass spectrometer ...