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G Protein Coupled Receptors Services
9 services found
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Endocannabinoids are amphipathilic molecules synthesized from phospholipids in the nervous system. They are a part of the endocannabinoid system, which includes G protein-coupled receptors. The most extensively studied endocannabinoids are N-arachidonoylethanolamine (anandamide) and 2-arachidonoylglycerol ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Many drugs target proteins that function as receptors for small-molecule ligands. These ligands bind to and alter the structures of their protein targets, thus modulating their biological activities. Key protein targets in the fields of biology and pharmaceutical research include the nuclear receptors (NRs) that ...
Manufactured by:Exscientia based inOxford, UNITED KINGDOM
Only with continual feedback between experiment and prediction can machine learning models be refined and deliver against complex therapeutic ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Leukotrienes (LTs) are a group of inflammatory lipid mediators derived from arachidonic acid (AA) via the 5-lipoxygenase (5-LOX) pathway. A characteristic feature of LTs is that they are produced by leukocytes and share a conjugated triene structure. LTs consist of cysteinylleukotrienes (CysLTs) and leukotriene B4 (LTB4). CysLTs contain a cysteine ring, whereas LTB4 is a noncysteine containing ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Prostaglandins (PG) are a group of lipid compounds with hormone-like effects that exhibit diverse physiological activities in animals. PG are enzymatically derived from fatty acids with 20 carbon atoms and a 5-carbon ring. They belong to a subfamily of eicosanoids and prostanoid class of fatty acid derivatives. PG have two main derivatives: prostacyclin and thromboxane. Prostacyclin is a potent ...
by:Eurofins Scientific based inKraainem, BELGIUM
Eurofins Genomics offers comprehensive genetic analysis of sample groups. Both single samples as well as batches of several thousand samples can be processed. For example, we offer genotyping for clinical trials according to the Good Laboratory Practice, GLP (OECD Guideline No.1 on the Principles of Good Laboratory Practice (ENV/MC/CHEM(98)17) and in accordance with the ICH Harmonized Tripartite ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Small molecules predominantly modulate the activity of their protein targets. The majority of approved small molecule inhibitors target intracellular kinases, which regulate cell signaling by transferring phosphate groups to target proteins. Contemporary research extensively focuses on targets implicated in protein-protein interactions, cancer metabolism, and immune ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Eicosanoid, including prostaglandin (PG), thromboxane (TX), leukotriene (LT), and lipoxin (LX), is critical signaling molecule. Prostanoid, a subset of eicosanoids, comprises PG and TX. Prostanoids are named based on the number of carbon-carbon double bonds in their molecules. Most biologically active PGs and TXs belong to the series 2 molecules with two carbon-carbon double bonds. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Receptors are biomolecules that can bind with hormones, neurotransmitters, drugs, or intracellular signaling molecules and are capable of inducing changes in cellular function. Receptors are categorized based on their cellular location into cell surface receptors and intracellular receptors. Each receptor typically has two active sites: one that recognizes and binds to the ligand and another ...