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Human Waste Into Disease Services
34 services found
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Recently developed CRISPR/Cas9-based screening methods have great potential for revealing the mechanisms and treatment strategies of human diseases, but there are still some biological studies that are not suitable for CRISPR knockout screening. CRISPRa and CRISPRi screening opens up many new possibilities. CRISPR/Cas9 PlatformCB provides custom libraries for any set of genes of interest, as ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Drug discovery has been considered as a high-cost and time-consuming process to treat different kinds of human ...
by:Nautilus Biotechnology based inSeattle, WASHINGTON (USA)
As we begin to scratch the surface of the true complexity and nuance of human health and disease, a breakthrough increase in proteomics analysis throughput will allow researchers to measure at the scale needed to power the studies needed to quickly and cost effectively discover these new diagnostic ...
by:Vertex Pharmaceuticals based inBoston, MASSACHUSETTS (USA)
Vertex is focused on discovering, developing and commercializing innovative medicines so people with serious diseases can lead better lives. Our scientists don’t see the impossible as an obstacle; they see it as a good place to start. These studies are investigating treatments or outcomes that have not all received approval from a health authority. The information presented is not intended ...
by:Doris Duke Charitable Foundation (DDCF) based inNew York, NEW YORK (USA)
Doris Duke was a significant supporter of medical research, making contributions to hospitals and research centers throughout her life. In her will, she expressed her interest in supporting “medical research designed to effectuate cures of major diseases.” ...
Manufactured by:TissUse GmbH based inBerlin, GERMANY
TissUse offers high-value service contracts to create custom solutions for safety evaluation of drugs, cosmetics and chemicals, and pre-clinical human disease modelling. Any new chip design serving customer needs with a specific organ arrangement can be prototyped and produced at short notice due to a proprietary rapid prototyping procedure established at TissUse. The versatile TissUse approach ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
The nucleic acid drug, as a novel therapeutic modality, can achieve long-lasting or even curative effects via gene regulations, replacement or editing. They have great potential to treat human diseases such as viral infections, cancers, and genetic ...
by:Amgen Inc. based inThousand Oaks, CALIFORNIA (USA)
Understanding the fundamental biological mechanisms of disease is a defining feature of Amgen's discovery research efforts—and a major contributor to the development of Amgen's deep and broad pipeline of potential new medicines. Amgen's "biology first" approach permits its scientists to first explore the complex molecular pathways of disease before determining what type of medicine, or ...
Manufactured by:Eagle Genomics based inCambridge, UNITED KINGDOM
Unifying constellations of complex, multi-dimensional data and the exploration of signals and networks of relationship undetectable by humans ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Drug discovery and development is an attractive strategy for treating various human diseases. In particular, different types of drugs, such as vaccines, antibodies, have been generated and tested in many preclinical and clinical trials. ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Autophagy is a key catabolic process that ensures the removal of excess or damaged cellular components under physiological and pathological conditions, and provides a metabolic supply in the absence of extracellular nutrients, thereby maintaining the proper balance of cells. Optimal autophagy activity plays an important protective role in several human diseases, such as neurodegenerative ...
by:The Ecological Society of America (ESA) based inWashington, DISTRICT OF COLUMBIA (USA)
Ecologists have discovered that many plants and animals produce chemicals that protect them from predators and diseases. Some of these same chemicals have been synthesized by scientists or harvested from the organism and used to treat human diseases. For example, the Pacific Yew tree produces a substance which is used in cancer treatments. Another example is a substance found in horseshoe crabs, ...
Manufactured by:Cloud-Clone Corp. based inKaty, TEXAS (USA)
The development of human disease is very complex, to itself as experimental object to in-depth study of the mechanism of disease, the accumulation of clinical experience not only in time and space are limited and many experiments on the moral are restricted. Animal models can provides the basic platform for the study of safety research of drugs, biological products, medical polymer materials, ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Genomic engineering in cell lines is a versatile tool for studying gene function, designing diseases models, biopharmaceutical research, drug discovery and many other applications. CRISPR (Clustered Regulatory Interspaced Short Palindromic Repeats)/Cas9 systems is a newly developed yet the most popular method for genome editing. It has been widely used in current biology, functional genome ...
Manufactured by:Galera Therapeutics, Inc. based inMalvern, PENNSYLVANIA (USA)
The cornerstone of our work is the recognition that oxygen metabolic pathways play important roles in human biology and ...
Manufactured by:Mimetas B.V. based inLeiden, NETHERLANDS
Capture and understand human disease biology in vitro. The key to unlocking effective therapies for the unsolved diseases of our times is a deep understanding of human disease biology. To this end, MIMETAS aims to capture the essence of diseases in fit-for-purpose in vitro models. We are fully committed to reducing human disease complexity into functional and screenable ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Enzymes are macromolecules with biocatalytic function to accelerate chemical reactions. Enzymes are indispensable in various functions of living organisms and play key roles in almost every physiological/pathological process such as signal transduction, cell regulation, metabolism, activity control and digestion. Strict control of enzyme activity is essential for homeostasis. Any malfunction of ...
Manufactured by:nVector based inPhoenix, ARIZONA (USA)
Traumatic brain injury (TBI) is a significant healthcare concern in the US, affecting 1.7 million individuals each year. There are approximately 1,365,000 emergency department visits each year for TBI, which equates to 3,740 per day. Of these, approximately 75% are the results of concussion and other forms of mild TBI. Falls are the leading cause of TBI, and motor vehicle accidents the leading ...
Manufactured by:AnaBios Corporation based inSan Diego, CALIFORNIA (USA)
EX VIVO Human Platforms for Cardiovascular Drug Discovery. Broadly defined, cardiovascular disease is the leading cause of death for men and women across most racial and ethnic groups in the United States with one person dying approximately every 34 seconds1. To drive successful clinical translation of new cardiovascular medicine, AnaBios develops relevant human ex vivo platforms for many ...
by:Selvita S.A. based inKrakow, POLAND
Having experience in both pharma and biotech R&D, we are well aware of what it means to discover a hit and transform it into a drug. You can best benefit from this “insider” experience through our integrated drug discovery services built ...