In Vivo Studies Services
17 services found
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Pharmacokinetics (PK) dedicated to determining the mechanisms of a drug's absorption, biodistribution, when it eliminated from the body and what it becomes. It is a study of how an organism affects a drug. In vivo PK studies are critical to ensure drug candidates have appropriate PK properties that can be evaluated in preclinical pharmacology and safety studies. In vivo PK studies provide ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
To overcome the weaknesses and limitations of current cell-based and animal-based testing, 3D models with the appropriate biophysical tissue architecture are generated for cardio-toxicity test in order to provide highly predictive and detailed information for the human in vivo study. Creative Bioarray offers the opportunity for highly predictable pre-clinical cardio-toxicity testing to help our ...
Manufactured by:Profacgen based inShirley, NEW YORK (USA)
Protein-protein interactions (PPIs) are crucial for understanding signaling cascades, predicting protein biological function, associating proteins with various diseases and insights into drug mechanism of ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Hepatotoxicity is one of the major reason for drug withdrawal from pharmaceutical development and clinical use. In vitro hepatotoxicity assays mimic in vivo tissue studies and in turn provide a reliable tool for safety assessment in the early stages of drug development. Creative Bioarray has developed standard and innovative in vitro models to address the need for early stage hepatotoxicity ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
In vivo studies are done toward the end of the lead optimization process on selected candidates for final characterization and selection. GLP studies are done only for development compounds being prepared for clinical trials. Creative Bioarray has conducted in vivo testing for cardiovascular disease using in vivo models for both side-effect profiling and efficacy according to your requirement. ...
by:Champions Oncology, Inc. based inHackensack, NEW JERSEY (USA)
Champions Oncology’s Analytical Testing platforms can be used to gather additional data at the endpoint of a preclinical model or ex vivo assay. Using multiplex cytokine assays with flow cytometry readouts, immune cell cytokine intracellular and extracellular staining upon activation can be assessed. Champions Oncology can also collect tissues from your in vivo studies and ...
by:Dyno Therapeutics based inWatertown, MASSACHUSETTS (USA)
Dyno’s lab provides the experimental capabilities that comprise the CapsidMap™ platform. The lab is responsible for creating novel vectors and assaying a diverse array of properties. Experiments at Dyno span pooled libraries with hundreds of thousands of AAV variants to assays focused on individual vectors. Our team rigorously employ diverse experimental approaches and innovate to ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Creative Biogene has developed the most experienced service of AAV, ranging from small crude scale to the large purified scale. We have the platform to offer the latest generation recombinant AAV stocks optimised for high levels of transgene expression and you can get reliable, reproducible, high purity, high titer vector stocks every time you order. Creative Biogene guarantees custom AAV ...
Manufactured by:Nexelis based inSeattle, WASHINGTON (USA)
Custom In Vivo Models and Testing Solutions. Selecting the appropriate in vivo model for your assays is critical for the success of your preclinical research program. At Nexelis, a Q² Solutions Company, we designed and developed disease specific in vivo models alongside bespoke personalized model development services. Our wealth of experience and capabilities allows us to help answer our ...
Manufactured by:Resonetics based inNashua, NEW HAMPSHIRE (USA)
Minimally invasive therapeutic and diagnostic medical products for: Electrophysiology cardiology, radiology, cryotherapy, drug delivery, pulmonology, gastroenterology, pain management, neurology. Catheter-orientated manufacturing process development. Supply chain selection, management, and technical oversight. In-vivo study protocol development, execution, reporting. Clinical site initiation, ...
by:OracleBio based inGlasgow, UNITED KINGDOM
At OracleBio, we have extensive experience in providing pre-clinical services to support clients in the early stages of the drug discovery pipeline. We understand that our clients need their data quickly, so we work hard to ensure a fast turnaround time, with a team of dedicated image analysis scientists and high-powered computing servers for fast image processing. ...
by:Biomcare ApS based inAarhus, DENMARK
It is often valuable to study the effect of a product on the gut microbiome or the influence of the microbiome on the effect of a new product, in a controlled setting that eliminates many of the confounding factors that affect the microbiome. Therefore, we offer in vivo tests of new products such as drugs and food ingredients including pre-tox studies, in an integrated workflow with microbiome ...
by:iFyber, LLC based inIthaca, NEW YORK (USA)
iFyber provides a suite of biofilm tests to verify the efficacy of antimicrobial medical devices and drugs. Biofilms are complex communities of microbes protected within a matrix of sugars, proteins, and extracellular DNA. These characteristics, in addition to their tolerance to antibiotics, make biofilms significantly more difficult to prevent and remove. Research has shown that between 60 to ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Kinases, in simple terms, are enzymes that transfer the phosphate groups of ATP to substrates. Kinases catalyze the transfer of γ-phosphate groups of ATP to substrates, mediate most signal transduction, and regulate a variety of cellular activities, including proliferation, survival, apoptosis, metabolism, transcription, differentiation, and a wide range of other cellular processes. ...
Manufactured by:InnoSer Belgie NV based inDiepenbeek, BELGIUM
We have specialized facilities for in vitro and in vivo offerings. Our established scientific experience and customized, collaborative approach make InnoSer the ideal ally for your company to achieve meaningful, high-quality and fast results. InnoSer facilitates scientific biomedical research in a professional, efficient and responsible manner. InnoSer is dedicated in facilitating your biomedical ...
by:North American Science Associates Inc.(NAMSA ) based inNorthwood, OHIO (USA)
If your device doesn’t perform according to its intended function, your agenda can be turned upside down. So when you’re looking for an accelerated path to market, you want a partner who offers a broad range of in vivo models and analytical tools that will provide you the data you need to support the specific application of your ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
The inauguration of monoclonal antibodies (mAbs), derived from mice, were immunogenic in humans. These molecules were first synthesized in 1975 by Georges Köhler and César Milstein through the use of hybridoma technology. Later, in 1984, another milestone was achieved with the production of chimeric human antibodies via recombinant DNA technology. Hybridoma technology facilitates the creation of ...