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Luminescence Services
7 services found
Manufactured by:Puracyp based inCarlsbad, CALIFORNIA (USA)
Puracyp’s cell lines can be used in a multiplex fashion that includes nuclear receptor activation data, cellular toxicity of test compounds, and to determine P450 metabolism of a luminescent substrate, such as P450 Glo™. Assessing P450 activity in Puracyp’s cell lines provides information to identify compounds that are both inducers and inhibitors. All of this ...
Manufactured by:Puracyp based inCarlsbad, CALIFORNIA (USA)
Our basic study design includes 6 concentrations in duplicate that can be used to calculate EC50 values (see figure below). Also included in the study results are positive and negative (solvent) controls and cell viability (reports toxicity of the test compound). A sample screening report is shown here. Once you receive your data, here is an explanation for interpreting the ...
by:Strateos Inc. based inMenlo Park, CALIFORNIA (USA)
Hit discovery or hit identification in drug development is driven by the need to identify small molecules with desirable activity in a compound screen against a target. Our state-of-the-art fully automated robotic platform is set-up to accelerate your drug discovery process starting with robust, targeted hit identification services. Our system can efficiently run biochemical, phenotypic and ...
by:iFyber, LLC based inIthaca, NEW YORK (USA)
At iFyber, we have access to state-of-the-art equipment and facilities that allow our highly trained staff to process and stain a variety of tissue types for research and development purposes. We specialize in working with clients across the medical device, wound care, and regenerative medicine fields to customize histological techniques for signal quantification or morphological measurements in ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Cell death occurs through several pathways including apoptosis, necrosis, and other emergent pathways. Apoptosis is pivotal in immune responses, involving processes such as intracellular balance, T cell clustering, the death of reactive lymphocytes, and cytotoxity of target cells. Apoptosis involves key components like APO-1/Fas, a receptor essential for apoptotic signaling; Caspase-3, crucial ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Obesity is a systemic disease, not only does it lead to changes in body shape, but it also brings along various diseases and complications, affecting an individual's overall health. Common complications, such as hyperglycemia, hyperlipidemia, and hypertension, are medically termed as "metabolic syndrome". The fluid factors secreted by adipose tissue propel the development of metabolic syndrome ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Metabolic bone disease encompasses a range of bone disorders caused by congenital or acquired factors that disrupt normal bone metabolism and biochemical states, leading to disorders in bone biochemistry and metabolism. These disorders stem from abnormalities in three key areas: bone resorption, bone growth, and mineral deposition. Increasingly, research has identified numerous cytokines involved ...