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Neurodegenerative Disease Services
26 services found
Manufactured by:Creative Biogene-Mitochondrial Research based inNY, NEW YORK (USA)
Neurodegenerative diseases (NDs) comprise a diverse set of pathological processes involving progressive neuronal dysfunction, degeneration, and death, leading to incurable and debilitating diseases. Creative Biogene provides a comprehensive range of services and products to assist researchers in neurodegeneration-related mitochondria ...
by:Neuron Experts based inMarseille, FRANCE
Advice in the preclinical development of new neuro-active compounds. The Neuron Experts team (operational and scientific) provides support and advice in your R&D programs and also in the development of new molecules in specific disease indications. ...
Manufactured by:Creative Biogene-Mitochondrial Research based inNY, NEW YORK (USA)
Creative Biogene provides the fractionated mitochondrial magnetic separation (FMMS) method to increase the production of brain-derived mitochondria compared with the UC method and can better detect mitochondrial damage in the central nervous system injury and neurodegenerative ...
Manufactured by:RareStone Group based inShanghai, CHINA
Rare neurological diseases include developmental defects of the nervous system, genetic and metabolic diseases, neuroimmune diseases, neurological tumors, special types of infectious diseases of the nervous system, neurodegenerative diseases, and neuromuscular diseases. At present, more than 7,000 rare diseases have been found in humans, about 60% of which are neurological diseases. ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Autophagy is a key catabolic process that ensures the removal of excess or damaged cellular components under physiological and pathological conditions, and provides a metabolic supply in the absence of extracellular nutrients, thereby maintaining the proper balance of cells. Optimal autophagy activity plays an important protective role in several human diseases, such as neurodegenerative ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Multiple Sclerosis (MS) is a chronic inflammatory neurodegenerative disease of the central nervous system (CNS). Experimental autoimmune encephalomyelitis (EAE) is the most common animal model of human MS as it is especially useful to investigate neuroinflammatory pathways and often serves as a "proof-of-principle" model for the efficacy of novel treatment strategies. ...
by:Neuron Experts based inMarseille, FRANCE
To keep up its high level of Competitiveness, Neuron Experts constantly develops new cellular models to provide the most accurate answers to customers’ needs: Development of new neurodegenerative disease models following current discoveries of new therapeutic targets, Development of new cellular models to study interaction between neurons and skin, Development of human Induced Pluripotent ...
Manufactured by:Neurodigitech, LLC based inEncinitas, CALIFORNIA (USA)
The NDT teams in specialized in both non-GLP and GLP compliant pre-clinical assessments of CNS disease therapeutics using a variety of biomarkers, including histology, immunohistochemical and histochemical methods. In particular, NDT is dedicated to custom-designed neuropathological assessments for the neurodegenerative diseases, such as Alzheimer's, Parkinson's, ALS, and brain insults (strokes ...
Manufactured by:MODAG GmbH based inWendelsheim, GERMANY
Multiple System Atrophy (MSA) is a rare neurodegenerative disorder that belongs to the group of synucleinopathies and is also classified as an “atypical parkinsonism” disorder. Pathologically, MSA is characterized by abnormal deposits of the α-synuclein protein mainly in oligodendroglial cells and also in certain nerve cells. Typically, there is a dysfunction of the autonomic ...
Manufactured by:GS International Trade Co.,Ltd based in, CHINA
Pharmaceutical Intermediate Key intermediate in drug R&D and production, particularly for anti-inflammatory, analgesic, or anticancer agents. Organic Synthesis Used as a precursor for synthesizing esters, amides, and other derivatives via epoxide ring-opening reactions. Drug Development Explored for its potential in treating cancers, neurodegenerative diseases, and as a drug carrier. Biochemical ...
Manufactured by:ReGen Therapeutics Limited based inLondon, UNITED KINGDOM
During ReGen’s discussions with potential licensing partners in 2004, it became apparent that a product based on the Colostrinin™ complex, as a whole, was more commercially attractive as a nutraceutical, rather than as a pharmaceutical. It was decided, therefore, to develop the original formulation of Colostrinin™ as a ...
by:Vaiomer based inLabège, FRANCE
Bacterial translocation: the missing link between intestinal microbiome and human complex non-communicable diseases. Complex disorders are multifactorial and often chronic, caused by genetic and environmental factors and comprising hundreds of conditions from cardio-metabolic diseases to neurodegenerative and mental disorders. These pathologies commonly present a low- to high-grade inflammation ...
Manufactured by:Neuron Bio based inGranada, SPAIN
Neuron Biolabs develops biosolutions for application in the pharmaceutical and agri-food industries through its specialised divisions. The Pharma division is dedicated fundamentally to the search for preventative drugs and treatments for neurodegenerative diseases, particularly Alzheimer’s disease. The Diagnostic division develops tools and biomarkers for the diagnosis of diseases of the ...
Manufactured by:Neuro Device Group S.A. based inWarszawa, POLAND
Neuroscience solutions that improve the quality of life. We specialize in the development of innovative solutions in the field of therapy and research of the brain and the central nervous system. We create neurostimulation methods, that solve unmet medical needs and improve the quality of human life. We create an image of modern ...
Manufactured by:Ozgene Pty Ltd. based inBentley DC, AUSTRALIA
Knockout mice are animal models that have been genetically modified to delete or inactivate a specific gene. The term ‘knockout’ refers to knocking out the functionality of the target gene. These mouse models allow researchers to gain insight into how the loss of the gene affects physiology, behavior and disease development. Observing the characteristics of a knockout phenotype can ...
Manufactured by:Advanced Brain Monitoring, Inc. based inCarlsbad, CALIFORNIA (USA)
Advanced Brain Monitoring provides full service EEG for clinical trials using the StatX Series wireless EEG systems administered concurrently with a full suite of tasks, including resting state and event-related related protocols. Stat X24 combines rapid application, low patient burden and disposable materials with high quality EEG acquisition easily performed in a clinical or home setting. Our ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Gangliosides are a large class of complex lipids that are abundant in the neuronal cell membranes in the brain. These molecules consist of sphingolipids with one or more sialic acids attached to the sugar chain. As structural components of cell membranes, gangliosides have their two hydrocarbon chains embedded in the plasma membrane, while the oligosaccharides are located on the cell surface, ...
Manufactured by:Arthus Biosystems, LLC based inChantilly, VIRGINIA (USA)
SAM analog and antibody: One of the important S-adenosylmethionine (SAM) analogs has a very good thermostability and yet a high hygroscopicity. This analog can also be used as a standard in in intro assays of ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Prostanoids, also known as eicosanoids, are a family of signaling molecules produced and secreted by various types of cells under both normal and pathological conditions. In the human body, these metabolites are excreted into body fluids such as plasma and urine. The precursors of prostanoids are 20-carbon polyunsaturated fatty acids (PUFAs) like arachidonic acid (C20:4), which are esterified in ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Proteolysis targeting chimera (PROTAC) drugs offer a novel approach to disease treatment by leveraging the body's innate protein degradation pathways. In contrast to traditional small-molecule inhibitors, PROTAC drugs promote the degradation of specific proteins rather than directly inhibiting their function, thus mitigating or eliminating their role in disease progression. ...