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Preclinical Pharmacology Services
3 services found
by:Oncodesign based inDijon, FRANCE
Establishing proof of concept in preclinical pharmacology is a critical step in the drug discovery process. This is one of the decisive factors in setting the therapeutic indication(s) targeted in clinical models and in the decision to continue a new product through the regulatory preclinical and clinical steps. For more than 25 years, Oncodesign ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
In vivo PK studies are critical to ensure drug candidates have appropriate PK properties that can be evaluated in preclinical pharmacology and safety studies. In vivo PK studies provide required and useful information that indicates human equivalent doses (HED), no effect levels (NOEL), and pharmacokinetic/pharmacodynamic (PK/PD) drivers. Conducting PK studies ...
by:elminda Ltd. based inHerzliya, ISRAEL
CNS drugs exhibit the lowest approval success rates due to multiple challenges such as lack of efficacy in early and advanced stages of development, Poor target selection / engagement, poor translation from pre-clinical models and disease heterogeneity. BNA may contribute in CNS research and drug development by adding new objective endpoints, assisting in understanding drug mechanism, identifying ...