Therapeutic Antibody Services
28 services found
Manufactured by:Absolute Antibody Ltd based inRedcar, UNITED KINGDOM
Absolute Antibody offers a quick and professional hybridoma sequencing service, also known as antibody sequencing. Hybridoma sequencing is the sequencing of the cDNA encoding the variable heavy (VH) and variable light (VL) domains of your hybridoma cell ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Therapeutic antibodies are highly regarded for their high affinity, specificity, low immunogenicity, and ability to target a wide range of biological molecules. Currently, mammalian cells, including Sp2/0, NS0, HEK293, and CHO cells, are primarily used for the production of therapeutic antibodies, with CHO cells accounting for over 70% of the production due to their complex posttranslational ...
Manufactured by:LenioBio GmbH based inDüsseldorf, GERMANY
We offer an end-to-end protein service for research-grade protein expression. From cloning to expression and purification, we enable our customers to unlock new potential for their research projects, without occupying their own resources. Combining the advantages of our versatile ALiCE® technology with our experience in protein production, our team of specialists will ensure you get the best ...
Manufactured by:Absolute Antibody Ltd based inRedcar, UNITED KINGDOM
Humanization is a critical step in the development pathway of all therapeutic antibodies derived from non-human sources, such as hybridomas. Absolute Antibody’s Prometheus™ antibody humanization service delivers a panel of humanized variants from your clone, guaranteeing to produce a variant with comparable activity to the parent antibody. Our service focuses on enhancing antibody ...
by:Biointron based inShanghai, CHINA
As a result of the advances in antibody discovery technologies in hybridoma, display libraries, Single B-cell sorting/sequencing and computational modeling, thousands of mAbs have been generated in antibody discovery campaigns. To rapidly find “best-in-class” antibody therapeutics, it has become essential to develop high throughput (HTP) processes that allow rapid assessment of ...
by:Genmab A/S based inCopenhagen V, DENMARK
Using our antibody expertise to transform how cancer is treated; As a leader in the discovery and development of antibody therapeutics, we are inspired by nature, passionate about innovation and driven by data. Our commitment to patients pushes us to use our antibody biology expertise to pursue and produce differentiated, next-generation cancer treatments. Our research and innovation teams ...
by:Biointron based inShanghai, CHINA
Nanobody (sdAb or VHH) is a promising next-generation therapeutic antibody technology for cancer immunotherapy and other applications. Nanobodies are distinguished from other conventional antibody formats by their unique properties of size, solubility, intrinsic stability, easy tailoring into pluripotent constructs, recognition of uncommon or hidden epitopes, binding into cavities or active sites ...
by:Genmab A/S based inCopenhagen V, DENMARK
We aim to invent, develop and commercialize differentiated antibody-based products, which can be utilized in a modular fashion to create unique and tailored therapeutics to transform cancer ...
Manufactured by:Synbio Technologies LLC based in, NEW JERSEY (USA)
Immunogenicity or Human Anti-Mouse Antibodies (HAMA) response is what happens when antibodies derived from xenogeneic sources are administered to humans. This can potentially decrease the effectiveness of immune-treatment through rapid clearance of the therapeutic antibody or immune-conjugate. In some cases, the patient may even develop an allergic sensitivity and be at risk of anaphylactic shock ...
Manufactured by:Novodiax, Inc. based inHayward, CALIFORNIA (USA)
Novodiax has developed a proprietary polymerized HRP (polyHRP) technology through intelligent structural designs and optimized polymerization. This new technology platform allows us to provide powerful tools and services for researchers who seek greater sensitivity and fewer workflow steps in their assay and product development ...
Manufactured by:ACROBiosystems based inNewark, DELAWARE (USA)
Anti-idiotypic antibodies are antibodies that target the variable region of another antibody to produce specific binding. These antibodies are widely used in drug development: they can be used as an important reference standard for immunogenicity analysis or can be developed to specifically detect antibody drug levels for pharmacokinetic studies. ACROBiosystems is committed to providing high ...
Manufactured by:Kiadis Pharma NV based inAmsterdam, NETHERLANDS
Our infectious disease work, in partnership with the Bill & Melinda Gates Foundation has built strong capabilities where we are developing product candidates that target pathogens that are predominant in the developing world. ...
Manufactured by:Aviva Systems Biology Corporation based inSan Diego, CALIFORNIA (USA)
Antibody based therapeutics constitutes a major portion of drug discovery research today. However, antibodies as drugs or diagnostic agents present significant analytical challenges because antibodies are large, complex, and heterogeneous molecules. Surface Plasmon Resonance (SPR) is a powerful analytical technology that is well suited for analyzing and characterizing antibodies. SPR can be used ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Creative Biolabs has extensive experience to offer the novel human or humanized antibody services for either therapeutic or laboratory applications. We have three routes in developing human antibodies. The first and most straightforward method is to screen our human antibody libraries. The second method is to immunize premade “humanized” mice and then raise hybridoma cell lines [or to ...
Manufactured by:Beta Lifescience based inPaoli, NEW JERSEY (USA)
Beta Lifesciences has accumulated an extensive experience in the development of recombinant proteins. We have rich experience in the expression of recombinant proteins (antibodies, enzymes, membrane proteins, cytokines, etc.) in any species. We provide recombinant protein expression and purification services from small-scale to large-scale. According to the customer's needs, our scientists will ...
Manufactured by:Absolute Antibody Ltd based inRedcar, UNITED KINGDOM
Polyclonal antibodies are widely used reagents across research and diagnostics. They are generated by immunizing animals with an immunogen and harvesting the animals’ blood to obtain immunoreactive serum. While polyclonal antibodies offer a range of advantages such as excellent performance across different methods, they suffer from high batch-to-batch variability and require the continued ...
by:Selvita S.A. based inKrakow, POLAND
Cell and Molecular Biology Department at Selvita performs In vitro comparative studies of biosimilar insulins and insulin analogs as well as battery of various therapeutic antibodies (e.g. TNFα, VEGF and HER2 inhibitors etc.). These studies should be comparative in nature and should be designed to have appropriate sensitivity to detect relevant differences in the response to the similar ...
by:Revvity Gene Delivery (formerly SIRION Biotech) based inHamburg, GERMANY
In the discovery of oncology therapeutics, Antibody-drug conjugates (ADCs) are rapidly gaining momentum, with hundreds of candidates advancing through clinical development. Whether your priority lies in assessing the epitope binding of your construct, evaluating the cytotoxic potency of the payload, or scrutinizing the efficacy of the linker in cleaving, each facet demands meticulous ...
Manufactured by:Ozgene Pty Ltd. based inBentley DC, AUSTRALIA
Humanized mice broadly refers to mice expressing human genes via transgenesis to gain relevant insights in the in vivo context for the understanding of human-specific physiology and pathology. Whilst many basic biological insights have been obtained from mouse studies, there are limitations to mouse models when investigating human biology. There are components of mouse biology systems that are ...
Manufactured by:Kiadis Pharma NV based inAmsterdam, NETHERLANDS
Innovative antibody-based molecular concepts. New treatments for cancer that leverage our own immune system to attack and destroy cancer cells can provide long-term and durable therapeutic responses in patients suffering from life-threatening malignancies. These benefits for patients have been driven by recently developed therapeutic antibodies binding with high specificity to drug targets on ...