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Ubiquitination Level Of A Protein Services
3 services found
by:Creative Proteomics based inNew York, NEW YORK (USA)
Ubiquitin is an about 8.5 kDa polypeptide consisting of 76 amino acids that is appended to the ε-NH2 of lysine in target proteins via the C-terminal glycine of ubiquitin. Following an initial monoubiquitination event, the formation of a ubiquitin polymer may occur, and polyubiquitinated proteins are then recognized by the 26S proteasome that catalyzes the degradation of the ubiquitinated ...
Manufactured by:Profacgen based inShirley, NEW YORK (USA)
Ubiquitylation is one of the most prevalent post-translational modifications (PTM) within cells. Ubiquitin modification induces protein degradation, which effect on protein function, localization and activity. Therefore, the study of protein ubiquitination plays an important role in cell biology and drug discovery. As a professional PROTAC services provider, Profacgen offers various ubiquitin ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
PROTACs represent a novel strategy for protein degradation that has gained prominence recently. Utilizing bifunctional molecules, PROTACs enable the targeted ubiquitination and subsequent degradation of proteins via the UPS. PROTACs can not only offer potential therapeutic applications for a variety of conditions, including cancer, immune dysregulation, viral infections, and neurodegenerative ...