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In Vitro Skin Models Services In Europe
14 services found
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Advances had been made towards the use of in vitro human skin equivalents/models for dermal drug and cosmetic product testing. In vitro Skin Models (Human Skin Equivalent, FTSK, HSE) used under defined test conditions offer several advantages: i) since most ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Hepatotoxicity is one of the major reason for drug withdrawal from pharmaceutical development and clinical use. In vitro hepatotoxicity assays mimic in vivo tissue studies and in turn provide a reliable tool for safety assessment in the early stages of drug development. Creative Bioarray has developed standard and innovative in vitro models to address the need for early stage hepatotoxicity ...
Manufactured by:Mimetas B.V. based inLeiden, NETHERLANDS
Capture and understand human disease biology in vitro. The key to unlocking effective therapies for the unsolved diseases of our times is a deep understanding of human disease biology. To this end, MIMETAS aims to capture the essence of diseases in fit-for-purpose in vitro models. We are fully committed to reducing human disease complexity into functional and screenable ...
Manufactured by:Newcells Biotech Limited based inNewcastle Upon Tyne, UNITED KINGDOM
Cross-species comparison of drug handling with near-physiological kidney transporter model. New drug molecules are usually tested in vivo in two preclinical species to gain a more detailed understanding of how they are transported and eliminated through the kidney and also to mitigate risk of renal toxicity in humans. However, these animal models are not always predictive of human responses. To ...
by:Revvity Gene Delivery (formerly SIRION Biotech) based inHamburg, GERMANY
In the discovery of oncology therapeutics, Antibody-drug conjugates (ADCs) are rapidly gaining momentum, with hundreds of candidates advancing through clinical development. Whether your priority lies in assessing the epitope binding of your construct, evaluating the cytotoxic potency of the payload, or scrutinizing the efficacy of the linker in cleaving, each facet demands meticulous ...
Manufactured by:InnoSer Belgie NV based inDiepenbeek, BELGIUM
In vitro and in vivo methods to provide a study setup that thoroughly determines safety and efficacy. ...
Manufactured by:CENTOGENE N.V. based inRostock, GERMANY
We work with partners to develop new disease models and new biomarkers of disease. We can also use our disease models to identify new drug targets and screen chemical compounds to identify potential new drug candidates. CENTOGENE provides companies with tools to accelerate drug discovery. From population screening studies that elucidate the prevalence of a rare disease to disease modeling, we are ...
Manufactured by:Alcyomics Ltd. based inNewcastle Upon Tyne, UNITED KINGDOM
Development of complex and functional high-throughput in-vitro 3D tissue models for replicating disease states and high-throughput molecule ...
Manufactured by:Neuron Bio based inGranada, SPAIN
Neuron Biolabs develops biosolutions for application in the pharmaceutical and agri-food industries through its specialised divisions. The Pharma division is dedicated fundamentally to the search for preventative drugs and treatments for neurodegenerative diseases, particularly Alzheimer’s disease. The Diagnostic division develops tools and biomarkers for the diagnosis of diseases of the ...
Manufactured by:Newcells Biotech Limited based inNewcastle Upon Tyne, UNITED KINGDOM
In vitro retinal disease modelling for retinal therapy. Newcells offers a fast and reliable in vitro safety and efficacy service for the evaluation of novel compounds for retinal therapy using complex human retinal organoid or RPE models developed in house. Both models are iPSC derived allowing gene-edited lines to be engineered using CRISPR/Cas9 for direct comparison between WT and mutant ...
Manufactured by:InnoSer Belgie NV based inDiepenbeek, BELGIUM
We optimize your lead compounds using expertise and data-driven decisions. The lead optimization stage marks the end of the drug discovery phase and the start of pharmaceutical or biological development. Insight into the absorption, distribution, metabolism, and excretion (ADME) is key to progressing your identified lead compounds after the hit to lead phase. ...
Manufactured by:InnoSer Belgie NV based inDiepenbeek, BELGIUM
We offer multi-validation solutions for preclinical targets across numerous therapeutic fields. ...
Manufactured by:InnoSer Belgie NV based inDiepenbeek, BELGIUM
We move your identified hits forward into in vivo testing and lead optimization. As a critical phase in your drug development journey, the hit to lead phase will determine which of your promising compounds will be characterized against your targets. With a lean ethos, InnoSer is dedicated to combining our expertise with your drug development goals in the most resource efficient way. During this ...
by:Oncodesign based inDijon, FRANCE
Establishing proof of concept in preclinical pharmacology is a critical step in the drug discovery process. This is one of the decisive factors in setting the therapeutic indication(s) targeted in clinical models and in the decision to continue a new product through the regulatory preclinical and clinical steps. For more than 25 years, Oncodesign has been a player known for its experience and ...