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Drug Candidates Services In Germany
13 services found
by:Reaction Biology Corp. based inMalvern, PENNSYLVANIA (USA)
Cell-based assays are valuable to probe new drug candidates in the environment of intact cells with physiologic concentrations of substrates, co-factors and ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
ADMET stands as an abbreviation for absorption, distribution, metabolism, excretion, and toxicity in pharmacokinetics and pharmacology. These properties describe the reaction of a drug medication within an organism, human, or animal, which helps scientists evaluate their drug candidates and select compounds that are likely to have the desired ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Antibody drugs which consist of antibody substances are prepared by antibody engineering technology based on cell and gene engineering technology. An important feature of antibody drugs is that they can be tailored making by genetic engineering and be prepared according to specific therapeutic needs. With the development of antibody genetic engineering ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Prior to clinical trials, it is necessary to conduct animal toxicity studies to best characterize the potential toxicity of new drug candidates. Generally, the objective of preclinical safety evaluation is to determine the toxic effects with respect to target organs, dose dependency, the relationship between clinical findings and exposure to the compound, and ...
Manufactured by:Atriva Therapeutics GmbH based inTübingen, GERMANY
The company’s lead drug candidate is the MEK inhibitor zapnometinib. The small molecule, which can be administered orally (tablet), is under advanced clinical development in two severe respiratory viral diseases: COVID-19 and influenza, two disease areas with urgent need for effective ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Pharmacokinetics (PK) dedicated to determining the mechanisms of a drug's absorption, biodistribution, when it eliminated from the body and what it becomes. It is a study of how an organism affects a drug. In vivo PK studies are critical to ensure drug candidates have appropriate PK properties that can be evaluated in preclinical ...
Manufactured by:CENTOGENE N.V. based inRostock, GERMANY
We work with partners to develop new disease models and new biomarkers of disease. We can also use our disease models to identify new drug targets and screen chemical compounds to identify potential new drug candidates. CENTOGENE provides companies with tools to accelerate drug discovery. From population screening studies that ...
by:Trion Research GmbH based inPuchheim, GERMANY
Moreover, we offer the full range of preclinical and clinical support from trial design over immunomonitoring and tumor biology analysis to data management and logistics solutions. We are particularly strong in supporting the development of innovative drugs. We work together with our partners to elucidate the modes of action of new compounds and to develop tailored approaches for ...
by:Trion Research GmbH based inPuchheim, GERMANY
Collaborations - In a team, you do better. We have established long-term partnerships with industry as well as several collaborations with leading academics in the disciplines that are relevant to the projects we support. We draw on the joint capabilities of this network to continuously improve our services and provide optimal assistance for each individual project at any ...
by:PharmAI GmbH based inDresden, GERMANY
Increase your success rate at an early stage. With pharmAI's rapid off-target prediction service you can already find potential off-targets during the discovery ...
Manufactured by:CENTOGENE N.V. based inRostock, GERMANY
We provide a broad range of services to successfully operate clinical trials. We leverage our proprietary Bio/Databank, multiomic platform, extensive physician network and our experts to ensure efficient and effective solutions to drive progress in the rare disease ...
by:Molecular Health GmbH based inHeidelberg, GERMANY
Act beyond human and experimental limitations. Knowledge to advance game-changing therapies from idea to market. The world's biomedical knowledge at your fingertips. Reliable predictions to anticipate risks. Interlinked data to find new targets and design novel drugs. Real-world evidence to evaluate success. These capabilities eliminate the uncertainties that limit drug development but are ...
by:Indivumed GmbH based inHamburg, GERMANY
Once a target is identified the various effects of the drug can be measured. This involves all read-outs we use during the biomarker validation but instead of looking at the effect of various candidates we focus on one component. As the tumor microenvironment can play an important role we focus especially on test methods involving fresh tissue. ...