- Home
- Services
- north america
- drug transporter interactions
Show results for
Refine by
Drug Transporter Interactions Services In North America
15 services found
Manufactured by:Puracyp based inCarlsbad, CALIFORNIA (USA)
Screening for nuclear receptor activation is a widely used and accepted practice to predict adverse drug effects and drug-drug interactions. Moreover, assessing nuclear receptor activation meets the latest FDA guidance for industry on Drug-Drug Interactions. Receptor activation screening services using Puracyp’s proprietary cell lines are available to identify NCEs that have the potential ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Early studies on the properties of drugs in ADMET mainly focused on human-derived or humanized tissue functional proteins as drug targets. Combined with in vitro research techniques and computer simulation, scientists study the interaction between drugs and in vivo biophysical and biochemical barrier factors. Alfa Chemistry can predict ADME parameters and pharmacokinetic properties by calculating ...
by:InterX based inBerkeley, CALIFORNIA (USA)
InterX operates at the nexus of academic research and pharma-tech industry. We partner with leading edge researchers, drug developers, and biotechnology companies across the globe to predict drug-target interactions using the most advanced computer algorithms ...
by:Helix Diagnostics based inWaterford Twp, MICHIGAN (USA)
Helix Diagnostics pharmacogenomics testing identifies unique variances on gene markers to determine an individual’s response to particular medications to create better treatment plans and improve outcomes. Reviewing patients genetic profile allows a much more personalized medicine approach and eliminates trial and error for more effective, quicker and safer therapies. ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Pooled Human Hepatocytes are the chief functional cells of the liver, responsible for the selective uptake, metabolism and excretion of most drugs. Cells for use in plate cultures or suspension assays represent a key tool for predicting properties such as hepatotoxicity, metabolism, and potential drug-drug interactions. Since these cells mimic the properties of the liver, researchers can evaluate ...
Manufactured by:Invicro, LLC based inNeedham, MASSACHUSETTS (USA)
Invicro’s early clinical imaging services deliver decision-making data for drug development teams in Phases 0, I and II. We have many years of pharma industry experience, and this understanding of the drug development process helps us design and execute pathology and imaging studies so that the resultant data reduces risk in later phases of development. We own and operate clinics in ...
by:Center for Toxicology and Environmental Health, L.L.C. (CTEH) based inNorth Little Rock, ARKANSAS (USA)
CTEH®’s pharmacology & toxicology professionals have extensive experience assessing the human toxicity of drugs and chemicals, and drug interactions and adverse reactions. CTEH® provides additional experience in pharmacokinetic analysis. Levels of drugs or chemicals in blood and/or urine are frequently key pieces of information in accidents, worker exposure issues, and in ...
Manufactured by:Charles River based inHollister, CALIFORNIA (USA)
Discovering and characterizing novel drug candidates for preclinical development depends on innovative and reliable science. Our unique combination of integrated, multidisciplinary drug discovery expertise and unparalleled scope of capabilities in targets, platforms, and therapeutic areas allow us to deliver depth and breadth in science with data and insight you can trust to progress your drug ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Creative Bioarray provides various in vitro ADME/PK services including high-throughput ADME screening, in vitro metabolism, in vitro permeability and transporter assays. ADME is short for "absorption, distribution, metabolism, and excretion". The four properties determine the drug level within a body, the drug exposure to tissues, and the metabolic process of a compound, which can help predict ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Generic peptide pharmaceuticals are products that replicate existing peptide drugs. These drugs are typically composed of amino acids linked by peptide bonds and are used to treat a variety of diseases, including cancer, diabetes, and immune disorders. Developing these generics requires comprehensive research into synthesis processes, formulation technologies, quality control, and bioequivalence ...
Manufactured by:Cloud-Clone Corp. based inKaty, TEXAS (USA)
Pharmacokinetics mainly study dynamic changes of drug metabolism in body, including drug absorption, distribution and excretion. The research will analyze the drugs and their metabolites by collecting samples in different tissues, organs at different time point. The pharmacokinetic experiments in vivo and in vitro can be designed according to customers’ ...
by:GENETWORx, LLC. based inGlen Allen, VIRGINIA (USA)
1 PCR Test Swab gives you: Detection of 30 Pathogens. Patient-Specific Antibiotic Resistance. 99% Accurate Results in 72 Hours. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Peptides are compounds formed by multiple amino acids linked by peptide bonds and can be prepared via recombinant DNA expression, biological extraction, or chemical synthesis. Peptides represent a unique class of drugs with certain characteristics of small molecule drugs as well as properties of large proteins and other biologics. Most intrinsic signaling molecules are peptide-based, such as ...
by:Inotiv based inWest Lafayette, INDIANA (USA)
Inotiv offers a broad scope of expertise for drug metabolism and pharmacokinetics (DMPK) studies at all stages of R&D, from lead optimization through NDA. Benefit from our long and impeccable regulatory history, world-class team of scientists, and 40+ year track record of providing leading pharma and biotech companies with attentive, decisive analytical services — and high-quality ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Many drugs target proteins that function as receptors for small-molecule ligands. These ligands bind to and alter the structures of their protein targets, thus modulating their biological activities. Key protein targets in the fields of biology and pharmaceutical research include the nuclear receptors (NRs) that belong to the superfamily of ligand-dependent transcription factors, the ...