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Drugs Design Services In North America
26 services found
by:Ainnocence Inc. based inSacramento, CALIFORNIA (USA)
Unlimited; Scalable, dynamic and cloud-native platform on AWS. Self-Evolving;Periodic updates with new data, knowledge and algorithm. Hands-Free;Simple and customizable work flow design. Secure;End-to-end encryption for user data and ...
by:Ainnocence Inc. based inSacramento, CALIFORNIA (USA)
Simple ; The SentinusAl platform performs antibody affinity optimization based on sequences only. Fast ; SentinusAI searches over a 10^10 mutations at 10,000x speed. Humanized ; SentinusAI replaces immunogenic residues with non-immunogenic ...
by:Ainnocence Inc. based inSacramento, CALIFORNIA (USA)
Concentrated; PharmCollectibles contains a highly selective chemical probe library for over 2,000 human target protein for efficient target identification. Representative; PharmaCollectibles condenses 14 million chemical compounds into a 50,000 compound library against a highly diverse set of ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
All combinatorial library methods include the following three main steps: library preparation, library components screening, and chemical structures of active compounds determination. The goal of chemical compound library design is to reduce the number of molecules as well as maintain the diversity of the library. Combinatorial library therefore has the potential of finding leads more rapidly ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Chemical space docking is a novel approach for virtual screening which allows for handling multiple molecules occurring in combinatorial chemical spaces. Chemical space docking aims to predict actives based on their binding mode after a docking procedure with subsequent scoring of the complexes. Yet the source of the docked molecules is no longer an enumerated library but a combinatorial built-up ...
by:SilcsBio, LLC based inBaltimore, MARYLAND (USA)
Guess work in drug discovery can be costly and time consuming. Our team is here to remove that for you. With us, your team ...
by:Ainnocence Inc. based inSacramento, CALIFORNIA (USA)
Simple : CarbonAI searches over 1.9 billion compounds to create synthesizable drug candidates – based only on target sequence. Precise : CarbonAI accurately identifies the most active and safe compound with a multi-objective optimization ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
Bioavailability refers to the degree and speed at which a drug is absorbed into the blood circulation. There are ongoing challenges with poorly water-soluble drugs and have failed to reach the market due to their poor water solubility. CD Formulation has developed a range of technologies and formulation expertise to improve the solubility and bioavailability of these drugs, helping customers find ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Nowadays, computational methods are routinely used to accelerate drug discovery process. In drug design and discovery, multiple computational chemistry approaches are employed to calculate and predict events, such as the drug binding to its target and the chemical properties for designing potential new ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
The nucleic acid drug, as a novel therapeutic modality, can achieve long-lasting or even curative effects via gene regulations, replacement or editing. They have great potential to treat human diseases such as viral infections, cancers, and genetic ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
Water vapor transmission capacity refers to the amount of water vapor through the specimen in a certain period of time under the specified temperature, relative humidity, and certain water vapor pressure. The main role of the drug bottle is to protect the safety of drugs in the process of storage and transportation, to ensure the stability of the validity period. Water vapor transmission amount ...
Manufactured by:Pluristem Therapeutics Inc. based inHaifa, ISRAEL
Bone marrow deficiency refers to a condition in which the hematopoietic stem cells in the bone marrow fail to produce enough, or produce abnormal, red blood cells, white blood cells and platelets. Hematopoietic cell transplantation (HCT), the transplantation of multipotent hematopoietic cells, is a standard treatment in various malignant and non-malignant conditions. Transplant patients are ...
by:ProXyChem based in, MASSACHUSETTS (USA)
ProXyChem provides the following services: In silico (virtual) screening to identify high probability hits (a low cost filter to experimental screening of millions of compounds) for lead generation. Lead optimization utilizing structure based drug ...
by:SilcsBio, LLC based inBaltimore, MARYLAND (USA)
The SilcsBio team provides expert services to make your structure-based drug design program more efficient, with increased speed and reduced ...
by:Canadian Light Source Inc. based inSaskatoon, SASKATCHEWAN (CANADA)
A special application of synchrotron light is the ability to elucidate the structure of proteins, a technique referred to as Protein Crystallography. The speed and accuracy of synchrotron protein crystallography is vital to genomics projects as well as drug design. Research into the 3-dimensional structure of proteins facilitates the development of ...
by:ProXyChem based in, MASSACHUSETTS (USA)
ProXyChem’s management, collectively, has over 40 years of drug discovery experience. We provide consulting services in all aspects of the drug discovery ...
Manufactured by:PharmaBlock Sciences (Nanjing), Inc. based inNanjing, CHINA
Virtual screening is a computational approach used to search libraries of small molecules in order to identify hit and even lead compounds. Because of its significantly lower cost, shorter turnaround time, and particularly access to libraries with substantial larger size compared to the traditional High Throughput Screening (HTS), it has quickly become one of the major drug discovery technologies ...
Manufactured by:XyloCor Therapeutics based inWayne, PENNSYLVANIA (USA)
Approximately 12 subjects (N=3 per cohort) who have refractory angina will be enrolled into 4 ascending dose groups, followed by an expansion of the highest tolerated dose with 21 additional subjects. The trial is designed to test the safety and tolerability of an investigational product called XC001. This is the first research study in which this drug will be ...
Manufactured by:Cirtec Medical based inBrooklyn Park, MINNESOTA (USA)
Precision Drug Therapies: Often designed as active implants, these devices are increasingly helping to treat chronic pain, cancer, diabetes and other conditions. Typical designs comprise a reservoir for medication, a battery-powered pump programmed to release the medication at prescribed dosages and intervals and a catheter that serves as the ...
Manufactured by:Pluristem Therapeutics Inc. based inHaifa, ISRAEL
Acute Radiation Syndrome (ARS) involves severe, potentially lethal damage to the bone marrow’s ability to produce blood cells, as well as to other systems and organs. Severe damage to bone marrow makes victims vulnerable to life-threatening hemorrhage, infection and anemia. ...