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Drug Molecule Services In United Kingdom
11 services found
Manufactured by:Newcells Biotech Limited based inNewcastle Upon Tyne, UNITED KINGDOM
Cross-species comparison of drug handling with near-physiological kidney transporter model. New drug molecules are usually tested in vivo in two preclinical species to gain a more detailed understanding of how they are transported and eliminated through the kidney and also to mitigate risk of renal toxicity in humans. ...
by:Acellera based inStanmore, UNITED KINGDOM
This protocol simulates the target of interest (GPCR, kinase, ion channel, etc.) in a solution of water and a co-solvent, like benzene or any other fragment-like molecule. During the simulation, the co-solvent molecules interact with the surface of the protein, revealing binding hotspots. These hotspots have been proven to correlate very well with actual pockets. ...
by:Lightcast Discovery Ltd. based inCambridge, UNITED KINGDOM
Finding rare events: The Lightcast platform is designed to have a high throughput and will be ideally suited to finding one in 10,000 or one in 100,000 ...
Manufactured by:Absolute Antibody Ltd based inRedcar, UNITED KINGDOM
Binding multiple epitopes with a single antibody offers several benefits. For example, one specificity may target individual molecules while another could recruit effector cells or deliver a drug to the target. Other options include dual-target bispecifics which might detect a desired cell type with much higher selectivity than a monospecific antibody. One of ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
The construction of an antibody-drug conjugate (ADC) is the covalent coupling of a monoclonal antibody and a toxic payload drug via a linker molecule. The ultimate goal for an ADC development project is to deploy the resulted ADC into in vivo systems, both in model animals and eventually human patients, to cure cancer and other diseases utilizing ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
mall molecule drugs are chemically synthesized active organic compounds with a low molecular weight usually less than 900 daltons which can be made into tablets or capsules that are easily absorbed. As traditional form of medicine, small molecule drugs have always been an important part of drug research and have ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
The construction of an antibody-drug conjugate (ADC) is the covalent coupling of a monoclonal antibody and a toxic payload drug via a linker molecule. The ultimate goal for an ADC development project is to deploy the resulted ADC into in vivo systems, both in model animals and eventually human patients, to cure cancer and other diseases utilizing ...
Manufactured by:Exscientia based inOxford, UNITED KINGDOM
Only with continual feedback between experiment and prediction can machine learning models be refined and deliver against complex therapeutic ...
by:OracleBio based inGlasgow, UNITED KINGDOM
At OracleBio, we have extensive experience in providing pre-clinical services to support clients in the early stages of the drug discovery pipeline. We understand that our clients need their data quickly, so we work hard to ensure a fast turnaround time, with a team of dedicated image analysis scientists and high-powered computing servers for fast image processing. ...
Manufactured by:Alcyomics Ltd. based inNewcastle Upon Tyne, UNITED KINGDOM
Preclinical safety and efficacy testing of drugs as “first in man studies”, sensitisation testing of chemicals and cosmetics, safety and efficacy testing of cellular therapies. Human in vitro tests as alternative to animal models. ...
Manufactured by:Micropore Technologies Ltd. based inRedcar,, UNITED KINGDOM
Commercialisation of sustained release formulations began in the 1970s with PLA & PGA used for surgical implants and sutures. PLGA (Poly (lactic acid-co-glycolic acid)) quickly emerged as the most important biocompatible, non-toxic polymer with numerous applications in drug delivery, tissue engineering, medical and surgical ...