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In Vitro Release Testing Services In United Kingdom
7 services found
by:Envigo based inCambridgeshire, UNITED KINGDOM
A Phase I study is a safety trial in a small number of healthy human volunteers or patients. It is typically the first human exposure to a New Chemical Entity (NCE) and takes place in a controlled clinical setting. To be granted permission by the regulatory bodies to perform such a study, a comprehensive package of toxicology data, demonstrating safety at many times the human dose in animals, ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Advances had been made towards the use of in vitro human skin equivalents/models for dermal drug and cosmetic product testing. In vitro Skin Models (Human Skin Equivalent, FTSK, HSE) used under defined test conditions offer several advantages: i) since most models are composed of primary human cells, inter-species extrapolation is avoided; ii) in contrast to human skin specimens, repeated ...
Manufactured by:CN Bio based inCambridge, UNITED KINGDOM
Employing our Liver-on-a-chip hepatic co-culture model (evaluated by our collaborators at the U.S. FDA), our DILI in vitro Service can screen your small molecules, antibodies, ASO, and gene editing reagents to establish human DILI ...
Manufactured by:Gentronix Ltd based inCheshire, UNITED KINGDOM
The in vitro micronucleus test (MNT) is a main-stay of most regulatory genotoxicity testing strategies, and is used to detect in vitro clastogens and aneugens. In this regard it complements the Ames test well, as between the two study types they detect all of the three major classes of genotoxin. Fluorescence In Situ Hybridisation (FISH) can also be conducted to differentiate predominantly ...
Manufactured by:Newcells Biotech Limited based inNewcastle Upon Tyne, UNITED KINGDOM
Accelerated in vitro evaluation of retinal toxicity. Newcells offers a fast and reliable retinal drug toxicity in vitro testing service using complex models developed in house: retinal organoids and RPE. The retinal toxicity service evaluates how new compounds affect cell viability, following photoreceptor degeneration or loss of RPE barrier function including outer segment photoreceptor ...
Manufactured by:Alcyomics Ltd. based inNewcastle Upon Tyne, UNITED KINGDOM
Preclinical safety and efficacy testing of drugs as “first in man studies”, sensitisation testing of chemicals and cosmetics, safety and efficacy testing of cellular therapies. Human in vitro tests as alternative to animal models. ...
Manufactured by:CD Bioparticles based inShirley, NEW YORK (USA)
CD Bioparticles offers one-stop drug-carrier complex analysis package service including drug in vitro testing using advanced techniques. Our experienced scientists have created a comprehensive platform to measure the drug in vitro testing from different ...