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Assay Services In Usa Massachusetts
26 services found
Manufactured by:Inovotion Sas based inLa Tronche, FRANCE
Target validation is an essential and critical phase of the drug discovery process. This is a crucial step before starting to develop a treatment based on a targeted protein that has been identified to play a role in the disease. The target protein’s role must be clearly identified before starting to develop a drug candidate against the disease and evaluate if the drug acts on the ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Ion channels are made up of special proteins produced by cells, which are aggregated and embedded in the cell membrane, forming pores occupied by water molecules. These pores are the channels for water-soluble substances, which can quickly enter and exit the ...
by:PathAI, Inc. based inBoston, MASSACHUSETTS (USA)
Rapidly advance your precision medicine strategy and move seamlessly from development to commercial launch with bespoke diagnostic assays and AI-powered companion ...
Manufactured by:Inovotion Sas based inLa Tronche, FRANCE
Pharmaceutical chemical and biology researchers need to develop new methods and models to improve the predictivity of preclinical discovery phases and increase the number of good molecules in clinic. INOVOTION’s unique in vivo technology will allow you to raise the global number of drug candidates tested in clinic without increasing your ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Kinases, in simple terms, are enzymes that transfer the phosphate groups of ATP to substrates. Kinases catalyze the transfer of γ-phosphate groups of ATP to substrates, mediate most signal transduction, and regulate a variety of cellular activities, including proliferation, survival, apoptosis, metabolism, transcription, differentiation, and a wide range of other cellular processes. ...
by:Dyno Therapeutics based inWatertown, MASSACHUSETTS (USA)
Dyno’s lab provides the experimental capabilities that comprise the CapsidMap™ platform. The lab is responsible for creating novel vectors and assaying a diverse array of properties. Experiments at Dyno span pooled libraries with hundreds of thousands of AAV variants to assays focused on individual vectors. Our team rigorously employ diverse ...
by:CJ Environmental, Inc. based inSharon, MASSACHUSETTS (USA)
We refine Gold, Silver, Platinum & Palladium from dental scrap using the most technologically advanced refining and assay equipment, allowing us to offer our clients unsurpassed returns for all of their precious metal dental ...
Manufactured by:Exosome Diagnostics, Inc. based inWaltham, MASSACHUSETTS (USA)
After marker identification, biomarkers and/or gene signatures enter our development process to become targeted assays. The newly identified biomarkers are developed into a Laboratory Developed Test (LDT) that will be run in Exosome Diagnostic’s CLIA and CAP accredited ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
T cells play a vital role in destroying pathogens and monitoring pathological cells. They are able to distinguish between self-antigens and non-self-antigens by surface T cell receptors (TCRs). Most human T cells express the classical TCRs, which consists of TCRα and TCRβ chains co-expressed with CD3 chains (γ, δ, ε, and ζ). ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
PROTACs represent a novel strategy for protein degradation that has gained prominence recently. Utilizing bifunctional molecules, PROTACs enable the targeted ubiquitination and subsequent degradation of proteins via the UPS. PROTACs can not only offer potential therapeutic applications for a variety of conditions, including cancer, immune dysregulation, viral infections, and neurodegenerative ...
Manufactured by:Pion based inBillerica, MASSACHUSETTS (USA)
Pion Analytical Services offers comprehensive support for drug development activities by providing sophisticated assays, analyses, and interpretations that help in understanding pharmacokinetic parameters at an early stage in the development process. With our advanced instrumentation, in vivo-level insights can be obtained in vitro. Our services include establishing primary ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Compared with genetic biomarkers, protein biomarkers provide higher degrees of differential information. Olink proteomics is based on a unique proximity extension assay (PEA) technique that enables simultaneous quantification of multiple protein ...
Manufactured by:Exosome Diagnostics, Inc. based inWaltham, MASSACHUSETTS (USA)
Cells from healthy and diseased tissues shed billions of exosomes into the blood and other biofluids; the resulting total exosome content is the accumulation of exosomes contributed from all tissue. Only a fraction of these exosomes are derived from a specific cell or tissue ...
Manufactured by:Exosome Diagnostics, Inc. based inWaltham, MASSACHUSETTS (USA)
Exosome Diagnostics partners with biopharma companies and Clinical Centers of Excellence to facilitate biomarker discovery programs in support of early discovery, translational, and clinical programs that may have companion diagnostic development needs. ...
by:Revvity Gene Delivery (formerly SIRION Biotech) based inHamburg, GERMANY
In the discovery of oncology therapeutics, Antibody-drug conjugates (ADCs) are rapidly gaining momentum, with hundreds of candidates advancing through clinical development. Whether your priority lies in assessing the epitope binding of your construct, evaluating the cytotoxic potency of the payload, or scrutinizing the efficacy of the linker in cleaving, each facet demands meticulous ...
by:Oncimmune Holdings PLC based inNottingham, UNITED KINGDOM
There has been an unprecedented response to the COVID-19 pandemic from the life sciences industry and research institutions to understand and respond to the effects of COVID-19, but despite first generation vaccines now being deployed to fight the disease, the need to expand our understanding of the immune response to SARS-CoV-2 still exists. Autoimmune reactions to the virus have been shown to ...
Manufactured by:Invicro, LLC based inNeedham, MASSACHUSETTS (USA)
Invicro’s Advanced Pathology Services (APS) team provides end-to-end solutions to support translational and clinical research by providing a combination of routine and unique tissue testing services. As part of the REALM IDx, Inc. group, our pathology service laboratories support projects spanning preclinical biomarker discovery research to clinical trials and development of companion ...
Manufactured by:Thermo Fisher Scientific based inWaltham, MASSACHUSETTS (USA)
In response to the novel coronavirus (SARS-CoV-2) outbreak, Thermo Fisher Scientific has worked rapidly to develop a multiplex real-time PCR diagnostic kit to enable clinical and public health laboratories to quickly diagnose COVID-19 caused by SARS-CoV-2 ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Biomarkers are measurable traits that serve as indicators of normal biological activities, disease processes, or pharmacological responses to therapeutic interventions. Peptides are particularly suitable as biomarkers due to their ability to circulate among various body compartments. Many disease processes can be inferred from the characteristic peptide profiles and pathological changes observed ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Systemic lupus erythematosus (SLE) is a classic systemic autoimmune disorder characterized by impaired autoimmune tolerance and high concentration of autoantibodies targeting self-antigens, which lead to organ damage. This pathological process involves multiple cytokines. ...