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Immunity Test System Services In Usa Massachusetts
16 services found
by:Dyno Therapeutics based inWatertown, MASSACHUSETTS (USA)
Dyno’s lab provides the experimental capabilities that comprise the CapsidMap™ platform. The lab is responsible for creating novel vectors and assaying a diverse array of properties. Experiments at Dyno span pooled libraries with hundreds of thousands of AAV variants to assays focused on individual vectors. Our team rigorously employ diverse experimental approaches and innovate to ...
by:Oncimmune Holdings PLC based inNottingham, UNITED KINGDOM
There has been an unprecedented response to the COVID-19 pandemic from the life sciences industry and research institutions to understand and respond to the effects of COVID-19, but despite first generation vaccines now being deployed to fight the disease, the need to expand our understanding of the immune response to SARS-CoV-2 still exists. Autoimmune reactions to the virus have been shown to ...
Manufactured by:Ozgene Pty Ltd. based inBentley DC, AUSTRALIA
Humanized mice broadly refers to mice expressing human genes via transgenesis to gain relevant insights in the in vivo context for the understanding of human-specific physiology and pathology. Whilst many basic biological insights have been obtained from mouse studies, there are limitations to mouse models when investigating human biology. There are components of mouse biology systems that are ...
by:Oncimmune Holdings PLC based inNottingham, UNITED KINGDOM
Viewing cancer through the immune lens (immuno-oncology) has led to the most promising advancements in cancer treatment in recent history, nonetheless the full potential of the approach is as yet ...
by:Oncimmune Holdings PLC based inNottingham, UNITED KINGDOM
Autoimmune disease is caused by the breaking of self-tolerance. Oncimmune’s understanding of the immune system as a mediator of disease powers the ImmunoINSIGHTS service for autoimmune ...
by:Oncimmune Holdings PLC based inNottingham, UNITED KINGDOM
EarlyCDT is a simple blood test that detects the elevated presence of autoantibodies generated by the body's immune system as a natural defence against cancer cells. EarlyCDT Lung is the world’s most thoroughly validated blood test for the detection of lung cancer and requires only a small volume of blood which can be taken ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Polyprenols are long-chain isoprenoid alcohols. The general formula for polyprenols is H-(C5H8)n-OH, where n refers to the number of isoprene units. Polyprenols are classified into three types: all-trans (solanesol-type), two-trans (Solanesol-type) and poly-cis (Betulaprenol-type), and three-trans and poly-cis (Ficaprenol-type). Despite their low content, polyprenols are natural bioregulators ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Antibodies (Abs) are essential components of the adaptive immune system, which can combat infections and other harmful agents. Produced by B cells, Ab is either secreted or expressed on the plasma membrane at the present of B cell receptors (BCRs). Each Ab comprises two heavy chains (VH) and two light chains (VL). The VL each include a constant region varing only across different classes and ...
by:TÜV SÜD America Inc. based inWakefield, MASSACHUSETTS (USA)
In the medical field, practitioners utilize a range of devices to address patient health, from diagnosis to surgery. When the patient comes into contact with a medical device or material, it should fulfill its intended function without harming the patient. Therefore, all medical devices need to undergo a thorough biological risk assessment to protect the patient from any toxic, physiological, ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
To maintain the immune system's homeostasis, multiple control systems are essential for managing infections, inhibiting tumor growth, preventing inflammation, and avoiding autoimmune diseases. T cells are known to be critical in this regulatory process. Specifically, Th3 cells primarily secrete TGF-β along with varying levels of IL-4 and IL-10. Natural regulatory T cells and Tr1 cells can ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Antibody therapies leverage human immune system antibodies to treat diseases by targeting specific proteins on pathogens or abnormal cells with exceptional precision. The development of antibody therapies has evolved from early polyclonal sera to monoclonal antibodies, and now to genetically engineered antibodies, focusing on enhancing drug safety, effectiveness, and manufacturing ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
PROTACs represent a novel strategy for protein degradation that has gained prominence recently. Utilizing bifunctional molecules, PROTACs enable the targeted ubiquitination and subsequent degradation of proteins via the UPS. PROTACs can not only offer potential therapeutic applications for a variety of conditions, including cancer, immune dysregulation, viral infections, and neurodegenerative ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Monoclonal antibodies (mAbs) are powerful therapeutic tools. These glycoproteins, belonging to the immunoglobulin (Ig) family, are utilized by the immune system to identify and neutralize foreign organisms or antigens. Ig’s are classified in five groups, IgA, IgD, IgE, IgG, and IgM (as α, δ, ε, γ, and μ), based on the structure of their constant regions. Among these, IgG subtypes—predominantly ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Tumor immunotherapy utilizes active or passive methods to provoke tumor-specific immune responses in the body, harnessing their inhibitory and cytotoxic functions against tumor cells. Characterized by its specificity, efficacy, and mitigation of collateral damage, immunotherapy distinguishes itself from conventional methods such as surgery, targeted therapy, and ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Nanoparticles (NPs) undergo interactions with serum proteins during systemic administration, which may result in the formation of protein corona (PC). Investigating the interplay between the chemical and biological properties of NPs enhances clinical translation efficiency. NPs with PC can be considered to exhibit a distinct biological ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
"Knocking out" related mammalian genes is an important method for studying gene function or its potential as a drug target, widely used in research on neurodegenerative diseases such as Alzheimer's disease, cancer, cardiovascular diseases, inflammation, or metabolic diseases. CRISPR/Cas9 is a revolutionary gene-editing technology that can precisely modify the genomic sequence. ...