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Tissue Accumulation And Species Specific Services In Usa Massachusetts
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Manufactured by:Exosome Diagnostics, Inc. based inWaltham, MASSACHUSETTS (USA)
Cells from healthy and diseased tissues shed billions of exosomes into the blood and other biofluids; the resulting total exosome content is the accumulation of exosomes contributed from all tissue. Only a fraction of these exosomes are derived from a specific cell or tissue ...
Manufactured by:Exosome Diagnostics, Inc. based inWaltham, MASSACHUSETTS (USA)
Exosome Diagnostics partners with biopharma companies and Clinical Centers of Excellence to facilitate biomarker discovery programs in support of early discovery, translational, and clinical programs that may have companion diagnostic development needs. ...
Manufactured by:Ozgene Pty Ltd. based inBentley DC, AUSTRALIA
Knock-in mice have an insertion in a specific locus in order to produce genetically modified mice for customised research purposes. Reporter genes, human genes, related genes from the same organism, or point mutations can be introduced into the protein-coding region of a gene to produce knock-in mice. The difference between the knock-in and knockout approach is that knock-in mouse models are ...
Manufactured by:Ozgene Pty Ltd. based inBentley DC, AUSTRALIA
The targeted transgenic mouse approach uses gene targeting by means of homologous recombination in embryonic stem (ES) cells. The transgene cDNA is knocked into a ‘safe habor’ locus in the mouse genome to generate transgenic mice with a predictable expression pattern without disturbing endogenous gene activity. Safe harbor loci have been utilised in the mouse to investigate gene ...
Manufactured by:Ozgene Pty Ltd. based inBentley DC, AUSTRALIA
Knockout mice are animal models that have been genetically modified to delete or inactivate a specific gene. The term ‘knockout’ refers to knocking out the functionality of the target gene. These mouse models allow researchers to gain insight into how the loss of the gene affects physiology, behavior and disease development. Observing the characteristics of a knockout phenotype can ...