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Drug Solubility Services In Usa New York
10 services found
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
CD Formulation provides a complete set of services for the development and manufacturing of improved drug solubility and bioavailability, including the provision of pH regulators, drug solubility evaluation, etc. We have quality systems, infrastructure, and capabilities to create a low-risk path for commercial production even ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
Industry estimates indicate that over 80% of new chemical entities exhibit low solubility, low bioavailability, and/or low or inconsistent dissolution rates. Effectively addressing these drug solubility, bioavailability, and dissolution rate issues is critical to advancing compound development and providing patients with the therapeutic benefits ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
Industry estimates indicate that over 80% of new chemical entities exhibit low solubility, low bioavailability, and/or low or inconsistent dissolution rates. Effectively addressing these drug solubility, bioavailability, and dissolution rate issues is critical to advancing compound development and providing patients with the therapeutic benefits ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
In Vitro Dissolution Assay: The dissolution rate test of the drug was determined using an in vitro dissolution assay. For poorly soluble drugs and their oral dosage forms, such as tablets, capsules and suspensions, the dissolution of the drug in the body fluids at the absorption site is the rate-limiting step in ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
Bioavailability refers to the degree and speed at which a drug is absorbed into the blood circulation. There are ongoing challenges with poorly water-soluble drugs and have failed to reach the market due to their poor water solubility. CD Formulation has developed a range of technologies and formulation expertise to improve the ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
Polymeric Microspheres Preparation: Microspheres are defined as spherical microscopic particles with sizes ranging from 1µm to 1,000 µm. Polymeric microspheres can be used for controlled and sustained release of active substances such as chemical drugs or therapeutic peptides. CD Formulation has specialized polymeric microsphere process technology that achieves programmable ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
About 40% of newly developed medicinal chemical entities have poor water solubility, and 90% of drugs under development can be classified as poorly soluble drugs. A solid dispersion (SD) refers to a dispersion system in which the drug particle size is within the range of 0.001 to 0.1 μm in a certain state and ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
At present, many drugs are often lower than the concentration required for treatment due to their low solubility, even in saturated solutions. For example, the solubility of chloramphenicol in water is 0.25%, and clinically, more than 12.5% solution is required for intramuscular or intravenous injection. In the pharmaceutical liquid preparation ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
CD Formulation's self-emulsifying drug delivery system service can evaluate the bioavailability of drugs and suggest suitable product solutions. Our professional team has the ability to establish and validate analytical methods, determine oil/water partition coefficients, investigate the equilibrium solubility of drugs in water, ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Creative Bioarray provides various in vitro ADME/PK services including high-throughput ADME screening, in vitro metabolism, in vitro permeability and transporter assays. ADME is short for "absorption, distribution, metabolism, and excretion". The four properties determine the drug level within a body, the drug exposure to tissues, and the metabolic process of a compound, which can help predict ...
