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In Vitro Services In Usa New York
40 services found
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
The ultimate goal for an ADC development project is to deploy the resulted ADC into in vivo systems, both in model animals and eventually human patients, to cure cancer and other diseases utilizing its payload efficacy. However, prior to in vivo deployment, information regarding basic biochemical characteristics and in vitro efficacy must be acquired for a proper evaluation of ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Advances had been made towards the use of in vitro human skin equivalents/models for dermal drug and cosmetic product testing. In vitro Skin Models (Human Skin Equivalent, FTSK, HSE) used under defined test conditions offer several advantages: i) since most models are composed of primary human cells, inter-species extrapolation is avoided; ii) in contrast to ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
In Vitro Dissolution Assay: The dissolution rate test of the drug was determined using an in vitro dissolution assay. For poorly soluble drugs and their oral dosage forms, such as tablets, capsules and suspensions, the dissolution of the drug in the body fluids at the absorption site is the rate-limiting step in drug absorption. ...
Manufactured by:CD Bioparticles based inShirley, NEW YORK (USA)
CD Bioparticles offers one-stop drug-carrier complex analysis package service including drug in vitro testing using advanced techniques. Our experienced scientists have created a comprehensive platform to measure the drug in vitro testing from different ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
Microspheres & Microneedles In Vitro Release Testing: For biodegradable materials, swelling and erosion mechanisms are also major factors controlling drug release. The composition, pH value, ionic strength, osmotic pressure and temperature of the release medium will all affect the release rate. The measurement of microsphere and microneedle in vitro release test ...
Manufactured by:Profacgen based inShirley, NEW YORK (USA)
Ubiquitylation is one of the most prevalent post-translational modifications (PTM) within cells. Ubiquitin modification induces protein degradation, which effect on protein function, localization and activity. Therefore, the study of protein ubiquitination plays an important role in cell biology and drug discovery. As a professional PROTAC services provider, Profacgen offers various ubiquitin ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
They are a class of cells isolated from early embryos (before the proto-intestinal stage) or primitive gonads, which have the properties of unlimited proliferation, self-renewal and multidirectional differentiation in vitro in culture. ES cells can be induced to differentiate into almost all cell types of the organism, both in vitro and in vivo ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Hepatotoxicity is one of the major reason for drug withdrawal from pharmaceutical development and clinical use. In vitro hepatotoxicity assays mimic in vivo tissue studies and in turn provide a reliable tool for safety assessment in the early stages of drug development. Creative Bioarray has developed standard and innovative in vitro models to address the need ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
The formation of Embryoid Body is a routine method for the differentiation of hiPSCs into different cell lineages. One of the major advantages of this method is that it is performed in vitro with standard tissue culture approaches and materials, thereby avoiding the regulatory problems and substantial costs associated with maintaining immunedeficient ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Creative Bioarray has deep expertise in the profiling, identification and structural characterization of metabolites in vitro and in vivo. We use advanced technology and software for accurate, reliable metabolite identification and structural characterization. In addition, synthetic chemistry services are available to undertake synthesis of metabolites, reference standards, and ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Creative Bioarray has deep expertise in the profiling, identification and structural characterization of metabolites in vitro and in vivo. We use advanced technology and software for accurate, reliable metabolite identification and structural characterization. In addition, synthetic chemistry services are available to undertake synthesis of metabolites, reference standards, and ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
The sponge mRNA contains multiple target sites complementary to a miRNA of interest. Stably expressed miRNA sponge is particularly valuable for long-term loss-of-function studies both in vitro and in vivo. Creative Biogene provides world-class MicroRNA (miRNA) sponge service and we have been perfecting MicroRNA sponge service for many years. Our microRNA sponge is a RNA molecule ...
Manufactured by:Creative Biogene-Mitochondrial Research based inNY, NEW YORK (USA)
Creative Biogene has established a complete and mature mitochondrial toxicity testing platform, which provides a complete solution for all stages of in vitro mitochondrial safety analysis and the determination of key parameters of mitochondrial ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
GFP Reporter Cell Line-4T1.2 is clonally derived from 4T1.2 cell line which was transduced by a lentiviral vector containing GFP and puromycin resistance gene. GFP is expressed as free cytoplasmatic proteins in these 4T1.2-GFP stable cells. It is a ready-to-use in vitro model for cell-based assay applications. ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
Melatonin Microneedle Patch Preparation: In order to avoid the first-pass effect, melatonin microneedles have been prepared to enable transdermal administration of melatonin, which is expected to improve its bioavailability; at the same time, microneedles are suitable for elderly people who cannot take the drug orally. CD Formulation provides melatonin microneedle patch preparation, microneedle ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
The method for generating iPSC-derived microglia mimics the in vivo pathway of development for brain resident macrophages and produces microglia that are representative of primary human microglia in vitro. ...
by:BSI Consulting based inHerndon, VIRGINIA (USA)
BSI Compliance Navigator is the smart, simple way to manage your regulatory information for Medical Device and In Vitro Diagnostic products with EU, UK and US requirements – helping you to get to market faster and maximize your ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Creative Bioarray has deep expertise in the profiling, identification and structural characterization of metabolites in vitro and in vivo. We use advanced technology and software for accurate, reliable metabolite identification and structural characterization. In addition, synthetic chemistry services are available to undertake synthesis of metabolites, reference standards, and ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Early studies on the properties of drugs in ADMET mainly focused on human-derived or humanized tissue functional proteins as drug targets. Combined with in vitro research techniques and computer simulation, scientists study the interaction between drugs and in vivo biophysical and biochemical barrier factors. Alfa Chemistry can predict ADME parameters and pharmacokinetic ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
At Creative Bioarray, cell line characterization is performed for master cell banks (MCB), working cell banks (WCB), and end-of-production cells (EPC) or cells at the limit (CAL) of in vitro cell age used for ...