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Pharmacokinetic Services In Usa New York
14 services found
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Pharmacokinetics (PK) models are generated to elucidate the transformations that a drug undergoes in an organism and the rules that determine this ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Pharmacokinetics (PK) studies provide critical information regarding the behavior of a drug in circulation and its ultimate form after extensive in vivo metabolism. Results from PK studies often serve as guidelines for clinical trials designs, especially in the development of an antibody-drug conjugate (ADC). Due to the heterogeneous nature of ADCs, multiple analytes have to be ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Creative Bioarray provides various in vitro ADME/PK services including high-throughput ADME screening, in vitro metabolism, in vitro permeability and transporter assays. ADME is short for "absorption, distribution, metabolism, and excretion". The four properties determine the drug level within a body, the drug exposure to tissues, and the metabolic process of a compound, which can help predict ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Pharmacokinetics (PK) studies provide critical information regarding the behavior of a drug in circulation and its ultimate form after extensive in vivo metabolism. Results from PK studies often serve as guidelines for clinical trials designs, especially in the development of an antibody-drug conjugate (ADC). Due to the heterogeneous nature of ADCs, multiple analytes have to be ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
ADMET stands as an abbreviation for absorption, distribution, metabolism, excretion, and toxicity in pharmacokinetics and pharmacology. These properties describe the reaction of a drug medication within an organism, human, or animal, which helps scientists evaluate their drug candidates and select compounds that are likely to have the desired effects on patients. ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
A large variety of animal models has been developed to provide investigators with the ability to characterize the pharmacokinetics and pharmacodynamics of ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Pharmacokinetics (PK) dedicated to determining the mechanisms of a drug's absorption, biodistribution, when it eliminated from the body and what it becomes. It is a study of how an organism affects a drug. In vivo PK studies are critical to ensure drug candidates have appropriate PK properties that can be evaluated in preclinical pharmacology and safety studies. In vivo PK ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
Solubility and bioavailability issues run through drug metabolism and pharmacokinetic evaluation of candidate compounds, preclinical prescription development, and commercial formulation development. From the toxicological evaluation stage, CD Formulation has a perfect drug metabolism and pharmacokinetic support system, each experiment only consumes ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Lead optimization is a complex and iterative process for identifying an improved drug lead with the goal of progressing to a preclinical candidate by altering the chemical structure of a confirmed hit. A diversity of properties such as target’s specificity, selectivity, pharmacodynamics, pharmacokinetics and toxicological properties are improved by modifying the chemical ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Combined with in vitro research techniques and computer simulation, scientists study the interaction between drugs and in vivo biophysical and biochemical barrier factors. Alfa Chemistry can predict ADME parameters and pharmacokinetic properties by calculating the physical and chemical indicators of one or more small molecules. We also study the drug-like properties and ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
CD Formulation researchers have conducted extensive research and development of drug delivery systems (DDS) in order to improve the pharmacokinetics and pharmacodynamics of drugs by delivering the required dose at the target site at the appropriate time and rate. Our drug delivery system development offerings include nanoparticles and particles, transdermal patches, and more. ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Alfa Chemistry is dedicated to providing pre-clinical drug research services to support our clients' drug development, pre-clinical and clinical investigations, and assist them in deciding which drug candidates are most worthwhile to pursue in clinical trials. We emphasize pharmacology, pharmacokinetics, medication safety assessment, and bioanalytical services in our customized ...
Manufactured by:Creative BioMart based in, NEW YORK (USA)
Creative Biomart provides drug analysis service for pre-clinical drugs and natural products on their physical and chemical properties. Our services include three main assays: pre-clinical pharmaceutical property analysis, pharmacokinetics analysis & bioanalysis, andnatural product ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Creative Biolabs developed a constrained peptide library construction technology, which offers constrained peptides with target-adapted cross-links. Our technology involves generating natural or semi-synthetic peptides with constrained structures to retain and improve the properties (e.g. stability, resistance to protease activity, protein binding affinity, intrinsic cell permeability, etc.) of ...