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Targeted Delivery And Protein Services In Usa New York
11 services found
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
The drug-discovery process is a trial-and-error run and time-consuming. Currently, using in silico tools to find a molecule that binds to the target protein has made computational chemistry a valuable tool in drug ...
by:Creative Proteomics based inNew York, NEW YORK (USA)
Ubiquitin is an about 8.5 kDa polypeptide consisting of 76 amino acids that is appended to the ε-NH2 of lysine in target proteins via the C-terminal glycine of ubiquitin. Following an initial monoubiquitination event, the formation of a ubiquitin polymer may occur, and polyubiquitinated proteins are then recognized by the 26S proteasome that catalyzes the degradation of the ubiquitinated ...
Manufactured by:Epigentek Group Inc. based inFarmingdale, NEW YORK (USA)
Chromatin immunoprecipitation (ChIP) offers an advantageous tool for studying protein-DNA interactions and can be used to determine whether a specific protein binds to a particular sequence of a gene, such as the target sequence of a transcription factor or to compare the levels of histone methylation associated with a specific gene promoter region between normal and diseased tissues. Identifying ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Protein kinases are involved in many cellular signaling pathways and comprise one of the largest families of homologous proteins. They play an extensive role in signal transduction and regulation of the complex cellular processes necessary to maintain life. Overexpression and/or dysregulation of protein kinases lead to a variety of diseases, thus providing numerous targets for drug development. ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Messenger RNA (mRNA) is responsible for transferring genetic information from DNA to proteins. With advances in in vitro transcription (IVT) technology, it has been possible to synthesize mRNA from either plasmid-based DNA templates or DNA PCR amplified from plasmids. mRNA synthesized by IVT methods could be sequence optimized to improve efficiency of translation as well as chemically modified to ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Creative Biolabs offers engineered protein scaffold library construction service. Our service has provided a strong foundation for the successful isolation and exploitation of high-affinity binders in the fields of research, diagnosis, and therapy. Creative Biolabs has developed trimer codon technology, which offers site-directed mutant library construction in a high-throughput and extremely ...
Manufactured by:Creative Biostructure based inShirley, NEW YORK (USA)
The formation of virus-like particles (VLPs) is a result of self-assembly of one or several types of viral structural proteins, such as Envelope or Capsid. The component proteins can originate from different viruses or be recombinantly expressed. Various systems have been used in the successful construction of VLPs from different sources including bacterial, yeast, insect cells, plant and ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Antibody characterization is important in research and biopharmaceutical development. All therapeutic proteins produced from current technologies have heterogeneities in the final product because various modifications occur during different stages of production. Due to these heterogeneities, thorough characterization is necessary for the reproducible and safe production of therapeutic ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Creative Biolabs has extensive experience to offer the novel human or humanized antibody services for either therapeutic or laboratory applications. We have three routes in developing human antibodies. The first and most straightforward method is to screen our human antibody libraries. The second method is to immunize premade “humanized” mice and then raise hybridoma cell lines [or to ...
Manufactured by:Creative Biostructure based inShirley, NEW YORK (USA)
Proteins are the building blocks of all living organisms and play crucial roles in biological processes. To investigate how a particular protein modulates biological processes, many aspects of the protein such as structure, modification, localization, interaction, and function need to be studied. A considerable number of proteins, especially membrane proteins, are screened in drug discovery as ...
Manufactured by:Profacgen based inShirley, NEW YORK (USA)
Ubiquitylation is one of the most prevalent post-translational modifications (PTM) within cells. Ubiquitin modification induces protein degradation, which effect on protein function, localization and activity. Therefore, the study of protein ubiquitination plays an important role in cell biology and drug discovery. As a professional PROTAC services provider, Profacgen offers various ubiquitin ...