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Crispr Services In Usa
16 services found
by:Synthego based inMenlo Park,, CALIFORNIA (USA)
For CRISPR-based therapies, understanding the potential and actual off-target edits associated with your CRISPR drug components is critical to their safety and efficacy. Synthego has partnered with SeQure Dx, a leading off-target editing analysis company, to bring you best-in-class OTE analysis for your RUO-to-GMP gRNAs. ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Recently developed CRISPR/Cas9-based screening methods have great potential for revealing the mechanisms and treatment strategies of human diseases, but there are still some biological studies that are not suitable for CRISPR knockout screening. CRISPRa and CRISPRi screening opens up many new possibilities. CRISPR/Cas9 PlatformCB provides custom ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Creative Biogene CRISPR/Cas9 PlatformCB has established a cost-effective, high-throughput strategy for identifying CRISPR/Cas-induced on/off-target mutations via deep sequencing of PCR amplicons. Based on years of experience in genome editing and off-target effects analysis, we offer one-stop solution to accurately detecting mutations induced by sequence-specific ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
CRISPR/Cas9 PlatformCB is a professional genetic editing biotechnology company that specializes in providing transgenic mouse models for biomedical research and drug discovery. CRISPR/Cas9 PlatformCB has independent experimental design strategies and verification methods, and successfully generated mouse models with fast turnaround and low cost. Based on our ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
dCas9 can be fused with a gene repressor protein, the KRAB protein, to form a complex CRISPRi (CRISPR interference) that inhibits gene expression. dCas9-KRAB targeting to the promoter region causes steric hindrance that halts transcript elongation by RNA polymerase, resulting in the target gene being repressed. CRISPR-based gene interference provides an efficient ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
CRISPR/Cas9 Platform provides one stop custom knock-in cell line generation service, including point mutation and gene insertion. With non-stop exploration of technology, we have developed an excellent platform for gene editing. Based on the platform, our expert staff has succeeded in dozens of knock-in cell line generation projects, including stem cells, tumor cells and even ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
CRISPR/Cas9 technology has been used as a genome-editing tool for multiple cell lines, such as tumor cell line and embryonic stem cell lines. Primary T cell, as an important class of immune cells system, play an extremely important role in immunity system. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
A key step in drug discovery is target identification—identifying "druggable" biological targets. After a target is identified, it must be validated to demonstrate the functional relationship between the target and disease phenotype while ensuring safety. The drug discovery process is lengthy and costly, but good target validation increases the likelihood of developing effective drugs and ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
With talented staffs, advanced technologies and state-of-the-art facilities, Creative Biogene provides microbial genome editing service, including traditional recombineering system, CRISPR/Cas 9 system and site-specific recombination ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
We mainly use the three approaches to abrogate gene function in zebrafish: stable lines carrying mutations (mutants); morpholino-based knock-down of gene function; and use of CRISPR/Cas9 gene editing to disrupt gene function in injected embryos. Many human pathological conditions from Alzheimer's disease to metabolic syndrome have been successfully modelled in zebrafish. ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Genomic engineering in cell lines is a versatile tool for studying gene function, designing diseases models, biopharmaceutical research, drug discovery and many other applications. CRISPR (Clustered Regulatory Interspaced Short Palindromic Repeats)/Cas9 systems is a newly developed yet the most popular method for genome editing. It has been widely used in current biology, ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
"Knocking out" related mammalian genes is an important method for studying gene function or its potential as a drug target, widely used in research on neurodegenerative diseases such as Alzheimer's disease, cancer, cardiovascular diseases, inflammation, or metabolic diseases. CRISPR/Cas9 is a revolutionary gene-editing technology that can precisely modify the genomic sequence. ...
by:InVivo Biosystems based inEugene, OREGON (USA)
Knockouts are the bread and butter of reverse genetic studies. They allow researchers to study the effects of the absence of a particular gene, protein segment, amino acid, or regulatory element, thereby enabling the researcher to determine their function. Gene knockouts are a commonly used tool for biologists to understand gene function. Examination of phenotypes when the gene is deleted can ...
by:Bio-Technical Resources, a Division of Arkion Life Sciences, LLC based inManitowoc, WISCONSIN (USA)
BTR microbiologists and molecular biologists have worked with a large spectrum of microorganisms. We have successfully applied two general approaches to strain development: Classic mutagenesis, screening and selection. Advanced recombinant ...
by:InVivo Biosystems based inEugene, OREGON (USA)
The nematode Caenorhabditis elegans is widely used in genetic and biomedical research. DNA fragment insertions can be introduced into the C. elegans genome. Our C. elegans knock-in services include point mutations, floxed alleles, degron tagging, fluorescent tagging and immunotagging. In the past 5 years, InVivo Biosystems has made over 600 fluorescent transgenic lines includuing 15 different ...
Manufactured by:CDBioSciences - VLPlant based inShirley, NEW YORK (USA)
cVLPs are formed from VLPs and ligands through genetic fusion or chemical conjugation. As a leading global provider of custom services, CD BioSciences has advanced facilities and experienced scientists dedicated to cVLPs development services to help our customers develop vaccines, nanomaterials and diagnostic ...