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In Vivo Models Services In Usa
16 services found
by:InVivo Biosystems based inEugene, OREGON (USA)
The MosSCI service enables you to integrate your desired sequence as a single copy insertion at a designated locus in the C. elegans genome. This is advantageous as it allows you to leave the native gene unmodified. With the MosSCI service you ...
by:InVivo Biosystems based inEugene, OREGON (USA)
Knockouts are the bread and butter of reverse genetic studies. They allow researchers to study the effects of the absence of a particular gene, protein segment, amino acid, or regulatory element, thereby enabling the researcher to determine their function. Gene knockouts are a commonly used tool for biologists to understand gene function. Examination of phenotypes when the gene is deleted can ...
by:InVivo Biosystems based inEugene, OREGON (USA)
The nematode Caenorhabditis elegans is widely used in genetic and biomedical research. DNA fragment insertions can be introduced into the C. elegans genome. Our C. elegans knock-in services include point mutations, floxed alleles, degron tagging, fluorescent tagging and immunotagging. In the past 5 years, InVivo Biosystems has made over 600 fluorescent transgenic lines includuing 15 different ...
by:InVivo Biosystems based inEugene, OREGON (USA)
Extrachromosomal arrays enable your desired construct to be expressed without being integrated into the genome. Using extrachromosomal arrays, you can choose to express a variety of configurations of transgenes, such as ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Nude rat xenograft models provide a more appropriate platform that conquers the limitations of traditional in vivo models and more precisely represent human cancer features especially in relation to metastasis and drug ...
Manufactured by:Nexelis based inSeattle, WASHINGTON (USA)
Custom In Vivo Models and Testing Solutions. Selecting the appropriate in vivo model for your assays is critical for the success of your preclinical research program. At Nexelis, a Q² Solutions Company, we designed and developed disease specific in vivo models alongside bespoke personalized ...
Manufactured by:vivoVerse Inc. based inAustin, TEXAS (USA)
C. elegans is recognized as a useful alternative in vivo model. The vivoChip® enables the use of C. elegans for high-content, multi-parametric analysis of neurodegeneration phenotypes from high-resolution fluorescence images of neurons. To demonstrate our unique capabilities, we studied dendritic neurodegeneration of dopaminergic neurons in C. elegans induced ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Moreover, autophagy has been highlighted as a crucial component of pathological processes such as cancer, hypoxia, pathogen infection, and neurodegeneration. Thus, the estimation of the rate of autophagy in a quantitative manner, especially in in vivo models, has become a vital need in the field. AAV Production ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
In vivo studies are done toward the end of the lead optimization process on selected candidates for final characterization and selection. GLP studies are done only for development compounds being prepared for clinical trials. Creative Bioarray has conducted in vivo testing for cardiovascular disease using in vivo models for both ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
CD34+ cells have been shown to possess colony-forming potential in short-term assays, maintain long-term colony-forming potential in in vitro culture, and allow the expression and differentiation of blood cells from different hematopoietic lineages in in vivo models. The CD34+ progenitor cells contain two main cell subpopulations, hematopoietic and endothelial ...
by:North American Science Associates Inc.(NAMSA ) based inNorthwood, OHIO (USA)
So when you’re looking for an accelerated path to market, you want a partner who offers a broad range of in vivo models and analytical tools that will provide you the data you need to support the specific application of your ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
The construction of an antibody-drug conjugate (ADC) is the covalent coupling of a monoclonal antibody and a toxic payload drug via a linker molecule. The ultimate goal for an ADC development project is to deploy the resulted ADC into in vivo systems, both in model animals and eventually human patients, to cure cancer and other diseases utilizing its payload ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
The construction of an antibody-drug conjugate (ADC) is the covalent coupling of a monoclonal antibody and a toxic payload drug via a linker molecule. The ultimate goal for an ADC development project is to deploy the resulted ADC into in vivo systems, both in model animals and eventually human patients, to cure cancer and other diseases utilizing its payload ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
Health Benefit Assessment for Veterinary Foods: With a deep understanding of the importance of optimal health in animals, CD Formulation offers a comprehensive suite of efficacy assessment services to scientifically validate the health benefits of new products. Through optimized in vivo and in vitro models, we evaluate formulations for functions such as immune ...
Manufactured by:Invicro, LLC based inNeedham, MASSACHUSETTS (USA)
Radiopharmaceutical therapies represent an effective way to treat solid cancers by using tumor targeting small molecules, peptides or biologics to deliver a cytotoxic payload that induces DNA damage in tumor cells, while limiting damage to normal and healthy tissue. Streamlined development, evaluation and clinical translation of radiopharmaceuticals requires a partner that has extensive ...
Manufactured by:Nexelis based inSeattle, WASHINGTON (USA)
Custom Assay Development to Advance Molecules. You need reliable approaches to support what’s next in your development programs whether they are complex small molecules, advanced biologics, or vaccines. At Nexelis, a Q² Solutions Company, we break down barriers to translational research through innovation and collaboration, helping you deliver better treatments to more patients, ...