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Mrna Services In Usa
23 services found
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Messenger RNA (mRNA) is responsible for transferring genetic information from DNA to proteins. With advances in in vitro transcription (IVT) technology, it has been possible to synthesize mRNA from either plasmid-based DNA templates or DNA PCR amplified from plasmids. mRNA synthesized by IVT methods could be sequence optimized to improve ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
mRNA medication is a novel therapeutic method that utilizes messenger RNA (mRNA). mRNA is a sequence of ribotide that encodes for proteins and can express specific proteins through the translation process within cells. The core principle of mRNA medications is to introduce designed mRNA molecules into the ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
In eukaryotic cells, the 3' end of mRNA is often extended with a poly(A) tail, a sequence of purine nucleotides. The poly(A) tail is a long chain of adenosine nucleotides of variable length. This tail is crucial for mRNA stability, transport, and translation. The analysis of mRNA's 3' poly(A) tail is a vital technique in studying the ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
mRNA vaccines offer numerous benefits, including cost-effectiveness, significant R&D flexibility, high manufacturing efficiency, exceptional safety profiles, and broad potential in the medical field. These novel vaccines necessitate stringent quality control measures to guarantee product stability and ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
The sponge mRNA contains multiple target sites complementary to a miRNA of interest. Stably expressed miRNA sponge is particularly valuable for long-term loss-of-function studies both in vitro and in vivo. Creative Biogene provides world-class MicroRNA (miRNA) sponge service and we have been perfecting MicroRNA sponge service for many years. Our microRNA sponge is a RNA molecule ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Cell morphology changes resulting from apoptosis include blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation, chromosomal DNA fragmentation, and global mRNA decay. Apoptosis is a highly regulated process and cannot stop once it has begun. Approximately 50 to 70 billion cells die each day in an average adult human due to apoptosis. ...
Manufactured by:Synbio Technologies LLC based in, NEW JERSEY (USA)
miRNAs are single stranded small non-coding RNA of 22 nucleotides that play important roles as endogenous gene regulators by mediating translation repression or promoting degradation of target mRNA. While the normal expression and function of miRNAs are vital for physiological processes, aberrant expression of miRNAs has been proved to be closely related to the occurrence of ...
Manufactured by:iRepertoire, Inc. based inHuntsville, ALABAMA (USA)
Multichain analysis in one single reaction mix is beneficial in that it saves rare and/or precious samples by using less RNA than traditional methods. Dam-PCR also allows for the detection of unique mRNA transcripts, which provides reduced bias, better error removal, and more precise data on clonotype ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Creative Biolabs can provide customized C. elegans gene editing services including vector construction, microinjection, mutant C. elegans identification, overexpression C. elegans screening, RNAi silencing effect evaluation, mRNA expression level detection, etc. ...
by:Thermo Fisher Scientific, LIMS & Laboratory Software based inPhiladelphia, PENNSYLVANIA (USA)
To support the manufacturing of Cell and Gene Therapies, we have developed innovative chromatography solutions, specifically designed to improve the downstream purification of mRNA and viral vectors such as the Adeno-Associated Virus (AAV), lentivirus, and ...
Manufactured by:Creative Biostructure based inShirley, NEW YORK (USA)
Most of these proteins are produced using cell-based or cell-free expression systems, which typically include the transcription of recombinant DNA into mRNA that is further translated into the protein under ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
One of the main obstacles in drug development is how to deliver drugs effectively to target cells. In general, macromolecules such as proteins and mRNA cannot penetrate the cell membrane because the cell membrane has acquired protective mechanisms through evolution. However, viruses can deliver their genetic material into cells. Therefore, viruses and virus-like particles are ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
With years of experience in the field of antibody development, Creative Biolabs has established a high-accuracy sequencing platform to provide top quality antibody sequence determination services from hybridoma cell lines. Creative Biolabs’ hybridoma sequencing service is highly versatile and is applicable for both IgG and IgM types of monoclonal antibodies produced by mouse and rat ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Creative Biolabs offers engineered protein scaffold library construction service. Our service has provided a strong foundation for the successful isolation and exploitation of high-affinity binders in the fields of research, diagnosis, and therapy. Creative Biolabs has developed trimer codon technology, which offers site-directed mutant library construction in a high-throughput and extremely ...
Manufactured by:Exosome Diagnostics, Inc. based inWaltham, MASSACHUSETTS (USA)
Exosome Diagnostics partners with biopharma companies and Clinical Centers of Excellence to facilitate biomarker discovery programs in support of early discovery, translational, and clinical programs that may have companion diagnostic development needs. ...
by:Nutcracker Therapeutics, Inc based inEmeryville, CALIFORNIA (USA)
RNA is often seen as a molecule with a supporting role in human physiology– a go-between for DNA and proteins. In fact, RNA is a macromolecule with immense versatility, which can be harnessed to tackle the most complex and difficult to treat ...
Manufactured by:Gene Tools, LLC based inPhilomath, OREGON (USA)
The exquisite properties of Morpholinos contribute to their high success rate, particularly as compared to Phosphorothioates or other unstable or nuclease-sensitive antisense structural types. However, occasionally Morpholino oligos can fail and there are many factors which can contribute to oligo failure, some correctable once determined. Some of the factors which contribute to failure and ...
Manufactured by:MedGenome Inc. based inCounty of New Castle, DELAWARE (USA)
Detailed RNA specific QC reports. Differential expression analysis. Pathway enrichment analysis. Fusion and splicing event analysis with interactive genome browser to visualize results. Proprietary tumor microenvironment ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Creative Biogene has built-up leading scientific, technical and commercial track records, successfully advancing therapeutic programs for numerous major industry and academic partners in a wide range of disease areas. With roots as a pioneer of genome-scale RNAi screening and long-standing contributions towards refining best practices in this field, Creative Biogene provides leading functional ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Creative Biolabs has been a long-term expert and market leader in the field of phage display and antibody engineering. Through our unparalleled phage display platform, Creative Biolabs offers integrated service of cDNA library construction to our customers over the ...