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Muscular Dystrophy Services In Usa
4 services found
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
DMD is a progressive muscle wasting disease that affects approximately 1 in 3500 male births. It is caused by mutations in a large 79-exon gene encoding the dystrophin protein. The majority of mutations identified in DMD are frameshift mutations that result in complete loss of dystrophin. Patients typically present at 2-5 years of age with a waddling gait, calf hypertrophy, and difficulties in ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Optimal autophagy activity plays an important protective role in several human diseases, such as neurodegenerative diseases, Parkinson's disease, hereditary myopathy, and melanin-deficient congenital muscular dystrophy. Therefore, monitoring autophagy can provide valuable insights into understanding human pathological mechanisms, developing new drugs, and ...
Manufactured by:Curi Bio based inSeattle, WASHINGTON (USA)
Curi Bio has a repository of iPSC’s for disease modeling and proprietary technologies for differentiating these cells into myoblasts and cardiomyocytes. Curi has developed in vitro 3D disease models for multiple disease phenotypes. In addition, Curi has the capability of generating new gene-edited iPSC models in ...
Manufactured by:InvivoSciences, Inc. (IVS) based inMadison, WISCONSIN (USA)
Human engineered tissue (EHT)-based high content analysis can be applied to drug discovery projects at their compound screening and lead optimization stage. Mass-produced human engineered tissues will recapitulate physiological functions of native tissues in micro tissues growing in 96-well plates or 384-well plates (coming soon). Patient-derived cells can also be used to fabricate engineered ...