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IGX Platform Software for Cancer Vaccines - Medical / Health Care - Pharmaceuticals

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Unlike conventional vaccination strategies, cancer vaccines are designed to mount responses against tumor-specific antigens, arising from somatic mutations specific to the cancer genome. They promise a highly tailored approach by targeting patient-specific neoantigens.

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The effectivity and ease of administration of vaccines have enabled their widespread use as the most important measure to protect from infectious disease. While cancer vaccines hold similar promise, their effectivity in clinical trials has so far been limited. More research is needed to understand the steps required to generate an effective anti-tumor immune response through vaccination. Combining high-resolution single-cell immunosequencing and broad-level bulk repertoire sequencing can provide important insights into the mechanistic underpinnings of vaccine-driven immune responses and advance both fundamental and translational research.

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