Enpicom B.V. applications

Unlike conventional vaccination strategies, cancer vaccines are designed to mount responses against tumor-specific antigens, arising from somatic mutations specific to the cancer genome. They promise a highly tailored approach by targeting patient-specific neoantigens.

Monoclonal antibodies (mAbs) are used to treat patients in a variety of conditions such as infectious disease, cancer, and autoimmunity. Discovery of therapeutic antibodies is a laborious process, that depends on high-throughput screening of antibody candidates to determine antigen specificity. Immune repertoire analysis provides accurate, sensitive, and rapid detection of antibody sequences in panning rounds or exposured animal models, accelerating the discovery of mAbs.

High-throughput analysis of immune repertoires has contributed to the elucidation of mechanistic underpinnings of autoimmunity, driving the development of novel therapies and better diagnostics.

No single preventive health intervention is more cost-effective than immunization. Immune repertoire analysis has taken a predominant role in the development of vaccination strategies against infectious disease and has enabled characterization of the immune response against pathogens at high resolution.