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Car T Cell Product Applications
5 applications found
Solid tumor-specific Affilin molecules are currently being evaluated as CAR-T ligands. Specifically, they were confirmed to be functionally expressed on the effector cell surface, mediate target cell-binding and effective target cell-killing in a dose-dependent fashion. Importantly they were just as effective as commonly used antibody ...
ByNavigo Proteins GmbH based in Halle, GERMANY
The manufacture of biopharmaceutical agents such as therapeutic monoclonal antibodies, vaccines and cell-based therapies like CAR-T cells require the highest quality control against the contamination of adventitious agents. These pathogens can enter the manufacturing process at multiple stages and impact yield and safety. Current methods for detection of adventitious agents are expensive, lack sensitivity and have long turn around times to results. Moreover, many of the current adventitious agent testing methods ...
ByAccuGenomics, Inc. based in Wilmington, NORTH CAROLINA (USA)
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Novel cell therapies show great promise as treatments for a variety of complex diseases including cancers and neurodegenerative disorders. Flow imaging microscopy supports drug product analysis in order to advance the development of these therapies. ...
ByYokogawa Fluid Imaging Technologies, Inc. based in Scarborough, MAINE (USA)
Monoclonal antibodies (mAbs) are used to treat patients in a variety of conditions such as infectious disease, cancer, and autoimmunity. Discovery of therapeutic antibodies is a laborious process, that depends on high-throughput screening of antibody candidates to determine antigen specificity. Immune repertoire analysis provides accurate, sensitive, and rapid detection of antibody sequences in panning rounds or exposured animal models, accelerating the discovery of ...
ByEnpicom B.V. based in s-Hertogenbosch, NETHERLANDS
Laser Force Cytology (LFC) and Radiance label-free approach to cell therapy research and biomanufacturing has significant value in expediting the process, decreasing costs, and ensuring therapy effectiveness and quality. Radiance enhances the highly complex biomanufacturing process for cell therapies by providing new insights to cell therapy research and process development. Current process development assays are fraught with difficult and time-consuming steps requiring highly skilled scientists and bioengineers ...
ByLumaCyte, Inc. based in Charlottesville, VIRGINIA (USA)