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Therapeutic Antibody Product Applications
10 applications found
Monoclonal antibodies (mAbs) are used to treat patients in a variety of conditions such as infectious disease, cancer, and autoimmunity. Discovery of therapeutic antibodies is a laborious process, that depends on high-throughput screening of antibody candidates to determine antigen specificity. Immune repertoire analysis provides accurate, sensitive, and rapid detection of antibody sequences in panning rounds or exposured animal ...
ByEnpicom B.V. based in s-Hertogenbosch, NETHERLANDS
Determining adverse immune responses to monoclonal ...
ByAlcyomics Ltd. based in Newcastle Upon Tyne, UNITED KINGDOM
No single preventive health intervention is more cost-effective than immunization. Immune repertoire analysis has taken a predominant role in the development of vaccination strategies against infectious disease and has enabled characterization of the immune response against pathogens at high ...
ByEnpicom B.V. based in s-Hertogenbosch, NETHERLANDS
Comprehensive antibody reactivity profiling: validate specificity, identify cross-reactions. The issue of antibody cross-reactivity is one that has often been often overlooked or sidelined in the past, with typical antibody QC involving evidence of binding to the intended target, while neglecting potential cross-reactivity. In recent years, however, many examples have come to light where poor validation of antibodies has led to misleading or erroneous conclusions for assays in which they are used as reagents, due ...
ByCambridge Protein Arrays Ltd. (CPAP) based in Cambridge, UNITED KINGDOM
As the COVID-19 pandemic continues, the SARS-CoV-2 virus is likely to become endemic with emerging novel variants, some of them seasonal. Updates to the various vaccines will be required, as will a range of anti-virals with a variety of mechanisms of action, for use in early infection and in hospitalizated patients, much like oseltamivir (Tamiflu) is used in certain populations for seasonal ...
ByCyrus Biotechnology Inc. based in Seattle, WASHINGTON (USA)
The manufacture of biopharmaceutical agents such as therapeutic monoclonal antibodies, vaccines and cell-based therapies like CAR-T cells require the highest quality control against the contamination of adventitious agents. ...
ByAccuGenomics, Inc. based in Wilmington, NORTH CAROLINA (USA)
The production of large quantities with the resulting complex requirements calls for automated process concepts. To achieve this, the machines for the essential process steps of washing, sterilizing, filling and closing are combined into one line. This creates a completely customer-centric line concept based on existing and proven technology. Automation of the filling process from washing to closing or even external cleaning leads to essential process reliability, with high transport capacities going hand in hand ...
ByRota Verpackungstechnik GmbH & Co.KG based in Wehr, GERMANY
Where does viscosity fit when it comes to the Pharmaceutical and Biotechnology Industry?. Protein-based drugs are the fastest growing class of drugs for the treatment of many diseases in humans, ranging from cancer to Alzheimer’s disease. Accurate viscosity values of proteins are essential in understanding behavior, designing delivery systems, and accurately determining particle size/hydrodynamic ...
ByRheoSense Inc based in San Ramo, CALIFORNIA (USA)
As targeted therapies evolve and the limitations of antibody-based therapies become clearer, a growing number of research teams are exploring the therapeutic potential of ...
ByBase Pair Biotechnologies, Inc. based in Pearland, TEXAS (USA)
The antibody drug discovery process differs from the traditional drug discovery of small molecules as it requires the development of hybridomas and the engineering of antibodies to recognize a specific target protein. The production of recombinant antibodies in cancer treatment as well as the development of neutralizing antibodies for infectious diseases, has allowed antibody discovery platforms to interrogate the immune repertoire and develop novel antibody libraries using flow cytometry analysis and cell ...
ByNanoCellect Biomedical, Inc. based in San Diego, CALIFORNIA (USA)