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Endocrine Disruption Articles & Analysis

49 articles found

How Lipid Metabolism Fuels Steroid Hormones and Why Their Analysis Matters

How Lipid Metabolism Fuels Steroid Hormones and Why Their Analysis Matters

Given their profound impact, it's clear that any disruption in their production, signaling, or metabolism can have significant health consequences. ...

ByCreative Proteomics


Cardiovascular Biology: Latest Research and Innovations

Cardiovascular Biology: Latest Research and Innovations

Understanding the Cardiovascular System The cardiovascular system comprises the heart, arteries, veins, and capillaries, which work together to transport oxygen and nutrients throughout the body. Any disruption in this system can lead to conditions such as hypertension, atherosclerosis, and heart failure. ...

ByCreative BioMart


Removal of Active Pharmaceutical Ingredients via Nyex Rosalox

Removal of Active Pharmaceutical Ingredients via Nyex Rosalox

A number of the emerging contaminants associated with having a harmful effect on the endocrine system have been recognized as endocrine disrupting chemicals. ...

ByCoftec


Using Chemcatcher to investigate the potential for remobilization of sediment-bound hormone-disrupting chemicals

Using Chemcatcher to investigate the potential for remobilization of sediment-bound hormone-disrupting chemicals

It has been well proven that endocrine-disrupting chemicals (EDCs) can accumulate in river sediments. ...

ByT.E Laboratories Ltd (TelLab)


EC Begins Public Consultations on Fitness Check of EU Legislation Regarding Endocrine Disruptors

EC Begins Public Consultations on Fitness Check of EU Legislation Regarding Endocrine Disruptors

The public consultation asks whether the EU should have the same approach across regulatory sectors (e.g., industrial chemicals, cosmetics, plant protection products, biocides, food) to identify endocrine disruptors and manage the risks of exposure to endocrine disruptors. ...

ByActa Group


Removing Pharmaceuticals and Personal Care Products From Drinking Water

Removing Pharmaceuticals and Personal Care Products From Drinking Water

The answer is that some PPCPs are known to disrupt the human endocrine system and can harm human health and the environment in other ways. ...

ByFluence Corporation


EU Endocrine Disrupting criteria will have various implications for industry

EU Endocrine Disrupting criteria will have various implications for industry

An assessment of the legal status of the substances with evidence or potential evidence of endocrine disrupting effects showed, that most of them are already subject to a ban or restriction or are addressed under existing Community legislation, although for reasons not necessarily related to endocrine disruption. ...

ByEnhesa - Global EHS & Product Compliance Assurance


Tissue explant co‐culture model of the hypothalamic‐pituitary‐gonadal‐liver axis of the fathead minnow (Pimephales promelas) as a predictive tool for endocrine disruption

Tissue explant co‐culture model of the hypothalamic‐pituitary‐gonadal‐liver axis of the fathead minnow (Pimephales promelas) as a predictive tool for endocrine disruption

Endocrine disrupting compounds (EDCs) can impact the reproductive system by interfering with the hypothalamic‐pituitary‐gonadal (HPG) axis. While in vitro testing methods have been developed to screen chemicals for endocrine disruption, extrapolation of in vitro response to in vivo action shows inconsistent accuracy. ...

ByJohn Wiley & Sons, Ltd.


Chronic exposure to mono‐(2‐ethylhexyl)‐phthalate causes endocrine disruption and reproductive dysfunction in zebrafish

Chronic exposure to mono‐(2‐ethylhexyl)‐phthalate causes endocrine disruption and reproductive dysfunction in zebrafish

Phthalic acid esters are frequently detected in aquatic environment. In this study, zebrafish were exposed to low concentrations (0, 0.46, 4.0, and 37.5 µg/L) of mono‐(2‐ethylhexyl) phthalate (MEHP) for 81 days, and the effects on reproduction, gamete quality, plasma vitellogenin (VTG), sex steroids, and transcriptional profiles of key genes involved in steroidogenesis were investigated. The ...

ByJohn Wiley & Sons, Ltd.


Endocrine Disruptors

Endocrine Disruptors

He also has hands-on experience assessing for potential endocrine disrupting effects of preservatives, sunscreens, fragrances, and antimicrobials. ...

ByBergeson & Campbell, P.C.


Potential estrogenic effects of wastewaters on gene expression in Pimephales promelas and fish assemblages in streams of southeastern New York

Potential estrogenic effects of wastewaters on gene expression in Pimephales promelas and fish assemblages in streams of southeastern New York

Direct linkages between endocrine‐disrupting compounds (EDCs) from municipal and industrial wastewaters and impacts on wild fish assemblages are rare. ...

ByJohn Wiley & Sons, Ltd.


Endocrine disrupting effect of the UV filter benzophenone‐3 in zebrafish, Danio rerio

Endocrine disrupting effect of the UV filter benzophenone‐3 in zebrafish, Danio rerio

The chemical UV filter benzophenone‐3 (BP‐3) is suspected to be an endocrine disruptor based on results from in vitro and in vivo testing. However, studies including endpoints of endocrine adversity are lacking. The present study investigated the potential endocrine disrupting effects of BP‐3 in zebrafish (Danio rerio) in the ...

ByJohn Wiley & Sons, Ltd.


The risk of endocrine disruption to fish in the Yellow River catchment in China assessed using a spatially‐explicit model

The risk of endocrine disruption to fish in the Yellow River catchment in China assessed using a spatially‐explicit model

The highest exposures were in the Fen and Wei tributaries. Endocrine disruption risk from estrogens was predicted to be minimal in the main stem. ...

ByJohn Wiley & Sons, Ltd.


Short term fish reproduction assays with methyl tertiary butyl ether (MTBE) with zebrafish and fathead minnow: Implications for evaluation of potential for endocrine activity

Short term fish reproduction assays with methyl tertiary butyl ether (MTBE) with zebrafish and fathead minnow: Implications for evaluation of potential for endocrine activity

This paper reports on short‐term fish reproduction assays in zebrafish and fathead minnow conducted to examine the potential for methyl tertiary butyl ether (MTBE) to cause effects on the endocrine system. Both studies were performed under Good Laboratory Practice and in accordance with OECD and USEPA test guidelines. ...

ByJohn Wiley & Sons, Ltd.


Bisphenol A reduces fertilizing ability and motility by compromising mitochondrial function of sperm

Bisphenol A reduces fertilizing ability and motility by compromising mitochondrial function of sperm

Bisphenol A acts as an endocrine disruptor, affects animal reproductive success in vivo, and affects sperm functions in vitro at environmentally relevant concentrations leading to reduction in sperm motility and fertilizing ability in fish. The effect of in vitro BPA on avian sperm functions has not been explored. We tested the effect of environmentally relevant concentrations of BPA (0, 0.18, ...

ByJohn Wiley & Sons, Ltd.


Adverse effects of thiram treated seed ingestion on the reproductive performance and the offspring immune function of the red‐legged partridge

Adverse effects of thiram treated seed ingestion on the reproductive performance and the offspring immune function of the red‐legged partridge

Pesticide research has traditionally focused on compounds with high acute toxicity and/or persistence, but the adverse sublethal effects of pesticides with different properties may also have important consequences on exposed wildlife. The authors studied the effects of thiram, a fungicide used for seed coating with known effects as endocrine disruptor. Red‐legged partridges (Alectoris rufa) ...

ByJohn Wiley & Sons, Ltd.


Metformin exposure at environmentally relevant concentrations causes potential endocrine disruption in adult male fish

Metformin exposure at environmentally relevant concentrations causes potential endocrine disruption in adult male fish

Interactions between insulin signaling and steroidogenesis suggest potential endocrine‐disrupting effects of metformin found in the aquatic environment. ...

ByJohn Wiley & Sons, Ltd.


Effects of progesterone and norethindrone on female fathead minnow (Pimephales promelas) steroidogenesis

Effects of progesterone and norethindrone on female fathead minnow (Pimephales promelas) steroidogenesis

As knowledge of contaminants capable of adversely modulating endocrine functions increases, attention is focused on the effects of synthetic progestins as environmental endocrine disrupters. ...

ByJohn Wiley & Sons, Ltd.


Characterization of trenbolone acetate and estradiol metabolite excretion profiles in implanted steers

Characterization of trenbolone acetate and estradiol metabolite excretion profiles in implanted steers

The environmental fate and transport of steroid growth promoters suggest potential for endocrine disrupting effects among ecological receptors; however, the initial excretion of steroid metabolites from cattle administered growth promoters has not been well characterized. ...

ByJohn Wiley & Sons, Ltd.


Persistence of endocrine disruption in zebrafish (Danio rerio) after discontinued exposure to the androgen 17β‐trenbolone

Persistence of endocrine disruption in zebrafish (Danio rerio) after discontinued exposure to the androgen 17β‐trenbolone

The aim of the present study was to investigate the effects of the androgenic endocrine disruptor 17β‐trenbolone on the sexual development of zebrafish (Danio rerio) with special emphasis on the question whether adverse outcomes of developmental exposure are reversible or persistent. An exposure scenario including a recovery phase was chosen to assess the potential reversibility of androgenic ...

ByJohn Wiley & Sons, Ltd.

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