Comparative Analysis of Combustible and Electronic Cigarette Exposure in KRAS-Mutant Lung Cancer

The increasing prevalence of electronic cigarette use, particularly among younger demographics, has prompted urgent investigation into its long-term health implications. While combustible cigarette smoke (CCS) is a well-established carcinogen, the oncogenic potential of electronic cigarette vapor (ECV) remains underexplored. A recent study led by Dr. Moghaddam et al. at The University of Texas MD Anderson Cancer Center provides a rigorous comparative analysis of CCS and ECV exposure in a KRAS-mutant lung adenocarcinoma (KM-LUAD) mouse model.