Allergen Specific Articles & Analysis
3 articles found
TSLP and Diseases TSLP and allergic reactions The discovery of the association between allergies and the activity of allergen-specific TH2 cells has led to the crucial hypothesis of the role of TSLP in the development and maintenance of atopic allergic diseases. ...
Cysteine proteases can induce non-classical monocytes in the lungs to produce the cytokine GM-CSF (granulocyte-macrophage colony-stimulating factor) through a mechanism that is not clear, and GM-CSF signaling can control LPS to inhibit Th2 cell responses to allergens, such as house dust mites. Therefore, because the protective effect of LPS depends on GM-CSF, the beneficial ...
In recent years test systems have been described that may be applied routinely to discriminate between contact allergens and irritants in vitro. Using human monocyte-derived dendritic cells (MoDC), this study was designed to refine the settings of a potential routine screening protocol for contact allergens and to investigate the so far poorly defined ...