Bioinformatics Tool Articles & Analysis
17 articles found
The significance of degradome sequencing lies in its ability to provide a more accurate and reliable identification of miRNA target genes compared to traditional bioinformatics predictions. By directly analyzing mRNA degradation fragments, researchers can validate miRNA interactions with target genes more effectively, thus simplifying subsequent experimental validation. ...
With the advancement of technology, high-throughput sequencing and mass spectrometry technologies have become powerful tools for identifying and quantifying glycosylation sites. These technologies can simultaneously analyze thousands to millions of protein samples, significantly improving the efficiency and accuracy of research. Bioinformatics plays an important ...
These providers leverage state-of-the-art molecular biology techniques and bioinformatics tools to deliver clonality analysis services tailored to client needs. ...
In recent years, the development of T cell antigen receptor sequencing technology has provided us with important tools for a deeper understanding of the function and diversity of T cells.T Cell Antigen Receptor Sequencing Technologies1. ...
Molecular Modeling and Structural PredictionBased on sequence information, computational tools can be used to predict the three-dimensional structure of the constant region to understand its possible spatial structure and functional relationship.3. Bioinformatics ToolsSpecial bioinformatics tools (such as IMGT, IgBLAST, etc.) are ...
Glycan arrays have emerged as powerful tools for studying the interactions between glycans and other molecules. ...
These providers leverage state-of-the-art molecular biology techniques and bioinformatics tools to deliver clonality analysis services tailored to client needs. ...
The stability modification of siRNA can improve its delivery efficiency in vivo, thus reducing the required siRNA dosage and immunogenicity. In addition, bioinformatics tools are useful in screening and can effectively avoid the off-target effect of siRNA. ...
The raw data obtained by sequencing is a sequence of only a few tens of bases in length, and the contigs that assemble these short sequences through bioinformatics tools are even the framework of the entire genome. Alternatively, these sequences are aligned to an existing genome or a similar species genome sequence, and further analyzed to obtain biologically ...
CD Genomics is a world-leading genomics services company that continues to innovate in high throughput sequencing services for the genomics industry, as well as genotyping, bioinformatics, microarrays, and more. The company has recently launched TCR-seq, a powerful service that enables rapid and efficient analysis of T-cell receptor (TCR) diversity and clonality, providing ...
Integration of data mining and bioinformatic tools to enable scientists to accelerate genomics-based crop improvement and ...
Bioinformatics is a discipline developed on the basis of biology, mathematics and computer science. It effectively acquires and analyzes biological data such as nucleic acid sequences and protein structures, so as to conduct comprehensive and accurate biological analysis. Bioinformatics is an extremely important tool to study the microorganisms, ...
We present the application of bioinformatics in the study and fight against cancer and infectious diseases. Bioinformatics as a Tool for Cancer Genomics Research The advent of bioinformatics has helped to rapidly and comprehensively process and analyze genome annotation, expression profiles and genomics data. ...
The rise of multi-omics technologies enables the detection of multiple molecular component differences in organisms, including genomics, transcriptomics, proteomics, and metabolomics. Sophisticated bioinformatics tools are able to reveal mitochondrial function and its contribution to cellular health and disease. ...
The appropriate bioinformatics approach depends on the sample preparation method and the type of sequencing platform. ...
Microbial bioinformatics may now be used to mine large metagenomic datasets for broad patterns that govern microbial communities. Typical metagenomic and bioinformatic investigations, on the other hand, do not fully characterize the ecology and evolution of microorganisms in their habitats. ...
The malaria vaccine which has been studied is designed to induce immunity to the sporozoite and to kill sporozoite-infected liver cells. A combination of bioinformatics approach and computational tools are used to screen and select antigen sequences as potential T-cell epitopes of supertype human leukocyte antigens (HLAs) alleles. ...