Biomarker Development Articles & Analysis
13 articles found
Alfa Cytology has announced cancer diagnostic biomarker development services to enhance precision in oncology research. ...
Bioinformatics AnalysisBioinformatics tools and software can be used to predict potential glycosylation sites by identifying possible glycosylation sites by analyzing the features of protein or nucleic acid sequences.Glycosylation plays a key role in the development of many diseases. For example, in cancer, abnormal glycosylation patterns may lead to changes in protein function, ...
For specific acetylation site localization, mass spectrometry is usually the preferred method.Changes in the acetylation level of a specific protein are related to the development of various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. ...
Cancer is a daunting diagnosis; however, the rapid advancements in oncology are continuously perfecting patient outcomes and quality of life. Among the groundbreaking developments, cancer vaccines are a promising frontier1. These vaccines are transforming how we approach cancer treatment, leveraging the body's immune system to fight malignancies more effectively. ...
By analyzing the changes of lipid biomarkers throughout the disease process and their interactions with other biomolecules, we can grasp the position of lipid metabolism disorders in the development of diseases as a whole and identify the possible pathogenesis. ...
Individuals with germline mutations in the CDH1 gene have a significantly increased risk of developing HDGC. Understanding the mechanisms underlying CDH1 loss and its impact on cancer progression is crucial for developing targeted therapies and improving patient outcomes. ...
Studies have shown that lncRNAs are quite complex in function and play an important role in various biological processes such as development, differentiation, proliferation, metastasis, apoptosis, stem cell pluripotency, and DNA damage. ...
LONDON, June 28, 2021 (GLOBE NEWSWIRE) – Treos Bio Limited (“Treos”), a clinical stage biotechnology company using data science and proprietary biomarkers to develop precision off-the-shelf and personalized peptide cancer immunotherapies, today announced the publication of a peer-reviewed article titled “A Peptide Vaccine Candidate ...
Oncimmune’s ImmunoINSIGHTS can leverage the power of these antibodies – regarded as sentinels of the adaptive immune response to cancer – as prospective biomarkers in immunotherapy development programmes. Our work has demonstrated the ability of autoantibodies to help predict therapy outcomes, immune-related adverse events (irAEs) and immune ...
Publication Summary: The identification of targets and biomarkers and development of therapeutics for nonalcoholic fatty liver disease (NAFLD) may be accelerated by the use of well-characterized primary cell and tissue reagents, as well as improved in vitro human cell-based disease models, including three-dimensional (3D) bioprinted liver tissue. ...
Other proteins with altered levels, such as Kunitz-type protease inhibitor 1 and beta-2-microglobulin, were not substrates in biochemical assays, suggesting an indirect affect of the MMPI, which might be important in drug development as biomarkers or, in preclinical phases, to predict systemic drug actions and adverse side effects. ...
This study was conducted in a contained environment in order to develop biomarkers and to evaluate the environmental damage after a release of two different toxic substances which are widely used in industrial production. ...
Mussels and other molluscs are used worldwide as sentinels in pollution monitoring. Recent years have seen the development of biological measurements (biomarkers) as tools for use in monitoring and environmental impact assessment, such biomarkers being indicative of contaminant exposure and/or impact. This paper describes established and ...