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Bioprinting Articles & Analysis

23 articles found

The Multi-faceted Application of Enzymes in Modern Biotechnology

The Multi-faceted Application of Enzymes in Modern Biotechnology

Enzyme-based bioinks are being developed for 3D bioprinting, creating living materials with tailored functions—offering tremendous promise for regenerative medicine and tissue engineering. ...

ByCreative Enzymes


Innovations in Clinical Medicine and Surgical Equipment

Innovations in Clinical Medicine and Surgical Equipment

Technologies such as the shoulder CPM (continuous passive motion) device and light-based bioprinters are redefining rehabilitation and regenerative medicine. From general surgery tables designed for optimal patient positioning to new muscle treatment approaches, medical equipment continues to evolve, ensuring better outcomes and improved patient ...

ByContent Management Test Company. Sugar


Bio-Ink: Printing the Future of Medicine and Beyond

Bio-Ink: Printing the Future of Medicine and Beyond

Bioactive factors: These are growth factors, nutrients, and other signaling molecules that can help the cells to survive, proliferate, and differentiate into the desired tissue type. How Does Bioprinting Work? Bioprinting is a complex process that involves using a specialized 3D printer to deposit layers of bio-ink onto a platform. ...

ByMatexcel


BeadReady™ successfully storing cells for 3D biofabrication

BeadReady™ successfully storing cells for 3D biofabrication

Connon, and Stephen Swioklo (2023), have successfully shown that Atelerix BeadReady™ is a simple, adaptable solution for room temperature cell storage in combination with biofabrication and how this can be integrated for on-demand bioprinting. Abstract Over the last decade, progress in three dimensional (3D) bioprinting has advanced considerably. ...

ByAtelerix Ltd


Cultured Protein: A Guide to Every Cell-Based Meat Startup in the World Right Now

Cultured Protein: A Guide to Every Cell-Based Meat Startup in the World Right Now

Co-founder Ryan Bethencourt is one of the investors behind Sustainable Food Ventures Cultivated Meat Startups Landscape: Enabling Technologies Here’s the full list in alphabetical order: Agulos Biotech (US, 2017, cell culture media) — developing Simulated Platelet Lysate (porcine), a replacement for FBS Back of the Yards Algae Sciences (US, 2018, cell culture media) — algae ...

ByAgulos Biotech, LLC


Fabrication And Characterization Of 3D Bioprinted Triple-Layered Human Alveolar Lung Models

Fabrication And Characterization Of 3D Bioprinted Triple-Layered Human Alveolar Lung Models

The selected 3D bioprinting approach offers an attractive tool for fabrication of 3D in-vitro human alveolar lung models. ...

ByRegenhu


Bioinspired Hydrogel To Improve The 3d Printability Of Mechanically Demanding Tissues Such As Intervertebral Disc

Bioinspired Hydrogel To Improve The 3d Printability Of Mechanically Demanding Tissues Such As Intervertebral Disc

The bioinspired hydrogel composition and processing parameters were optimized to improve the quality of the constructs fabricated through micro-extrusion technology by means of REGENHU 3D Bioprinters. By exploiting the dedicated design software and high-accuracy automated calibration mechanisms of the system, researchers were able to perform the process directly within Petri ...

ByRegenhu


Fabrication Of In-Vitro Phenotypically Stable Engineered Articular Cartilage

Fabrication Of In-Vitro Phenotypically Stable Engineered Articular Cartilage

The bioprinted constructs allowed the in vitro study of chondrogenic signaling pathways, as well as the role of TGF-β signaling. ...

ByRegenhu


3D Bioprinting Of Prevascularised Implants For The Repair Of Critically-Sized Bone Defects

3D Bioprinting Of Prevascularised Implants For The Repair Of Critically-Sized Bone Defects

The aim of this study was to develop a bioprinting strategy to engineer prevascularised tissues in vitro and to investigate the capacity of such constructs to enhance the vascularisation and regeneration of large bone defects in vivo. ...

ByRegenhu


Bioprinting Algae To Improve Tissue Oxygenation

Bioprinting Algae To Improve Tissue Oxygenation

These Allevi Authors set out to develop a natural method for sustained oxygen release into an engineered tissue and found a solution in nature. Their novel bioprinting method uses an Allevi 2 bioprinter and a bioink that incorporates photosynthetic single-celled green algae called Chlamydomonas reinhardtii. ...

ByAllevi, Inc.


Improved 3D Liver Model Could Forever Change Drug Testing – Allevi Author

Improved 3D Liver Model Could Forever Change Drug Testing – Allevi Author

To achieve this, the researchers lowered both GelMA and LAP photoinitiator concentrations in their final constructs to as low as 5% and 0.1% w/v, respectively. They bioprinted the constructs using an Allevi 2 bioprinter and the following parameters: Print Speed (mm/s)Tip GaugeTemperature (C)Pressure (PSI)Crosslinking IntensityCrosslinking Time (s)Crosslinking ...

ByAllevi, Inc.


IMCAS Americas 2019 Shined in Sunny Cartagena

IMCAS Americas 2019 Shined in Sunny Cartagena

Jean-Yves Coste, Senior Healthcare Director of Michel Dyens & Co. in Paris spoke on trends in medical aesthetics, including telediagnoses, digital imaging, 3D bioprinting in reconstructive surgery, and what he referred to as IOMT (Internet of Medical Things). ...

ByDyve Biosciences


SPACE BIO-3D PRINTING FROM HUMAN CARTILAGE TO THYROID GLAND IN RODENTS AND TO SPACE ARTIFICIAL MEAT

SPACE BIO-3D PRINTING FROM HUMAN CARTILAGE TO THYROID GLAND IN RODENTS AND TO SPACE ARTIFICIAL MEAT

Researchers are curious about how microgravity can facilitate bioprinting and the growth of cells and tissues. At the same time, the recent use of this technology in space to examine other medical problems has also interested them, such as radiation and human problems. ...

BySunkye International Co., LTD.


Bioprinted pluripotent stem cell-derived kidney organoids provide opportunities for high content screening

Bioprinted pluripotent stem cell-derived kidney organoids provide opportunities for high content screening

Utilization of a bioprinter allows for the generation of large numbers of uniform and highly reproducible organoids in reduced time (approximately 20x faster) compared to manual processes. Treatment of bioprinted kidney organoids cultured in conventional 6-well format with doxorubicin exhibited concentration-dependent morphological changes consistent with cell ...

ByOrganovo Holdings Inc.


Cells isolated from donors with nonalcoholic fatty liver disease exhibit disease phenotypes in 3D bioprinted human liver tissue

Cells isolated from donors with nonalcoholic fatty liver disease exhibit disease phenotypes in 3D bioprinted human liver tissue

Publication Summary: The identification of targets and biomarkers and development of therapeutics for nonalcoholic fatty liver disease (NAFLD) may be accelerated by the use of well-characterized primary cell and tissue reagents, as well as improved in vitro human cell-based disease models, including three-dimensional (3D) bioprinted liver tissue. The characteristics of donors ...

ByOrganovo Holdings Inc.


LLNL Uses 3D Bioprinting to Produce Live Cells

LLNL Uses 3D Bioprinting to Produce Live Cells

On March 5, 2019, the Lawrence Livermore National Laboratory (LLNL) announced that their researchers have 3D printed live cells that are able to convert glucose to ethanol and carbon dioxide gas. The substance produced from this conversion resembles beer. This means that this newly developed technology can lead to highly efficient biocatalysis. According to LLNL’s announcement, the use ...

ByBergeson & Campbell, P.C.


	 A human in vitro three-dimensional bioprinted liver tissue system can be used to model nutritional damage and protective effects of MSDC-0602K, a novel modulator of the mitochondrial pyruvate carrier (MPC)

A human in vitro three-dimensional bioprinted liver tissue system can be used to model nutritional damage and protective effects of MSDC-0602K, a novel modulator of the mitochondrial pyruvate carrier (MPC)

Publication Summary: The growing global incidence of NASH mirrors the availability of nutrients. Over-nutrition also results in insulin resistance and type-2 diabetes, which are often co-morbidities associated with NASH and are known to drive more adverse outcomes. MSDC-0602K, a modulator of the mitochondrial pyruvate carrier (MPC), is in clinical trials as a potential treatment for NASH. ...

ByOrganovo Holdings Inc.


Modeling NAFLD using 3D bioprinted human liver tissue

Modeling NAFLD using 3D bioprinted human liver tissue

Publication Summary: Nonalcoholic fatty liver disease (NAFLD) is a chronic condition that originates as lipid accumulation within hepatocytes (steatosis) and progresses into nonalcoholic steatohepatitis (NASH), characterized by lipid accumulation, inflammation, oxidative stress, and fibrosis. NAFLD is now recognized as the most common cause of chronic liver disease in the western world, with an ...

ByOrganovo Holdings Inc.


	 Utilization of a 3D bioprinted liver tissue model to evaluate the antifibrotic effects of an ALK5 inhibitor in a TGFß-induced model of hepatic fibrosis

Utilization of a 3D bioprinted liver tissue model to evaluate the antifibrotic effects of an ALK5 inhibitor in a TGFß-induced model of hepatic fibrosis

Evaluation of potential antifibrotic therapies are limited using conventional non-human animal models, due to their inability to accurately reflect complex in vivo human biology, while 2D models lack the multicellular complexity and life span required to study fibrosis progression and regression. Utilization of a human 3D-bioprinted liver tissue model (ExVive™ Human Liver ...

ByOrganovo Holdings Inc.


Modeling NAFLD using 3D bioprinted human liver tissue

Modeling NAFLD using 3D bioprinted human liver tissue

Publication Summary: Nonalcoholic fatty liver disease (NAFLD) is a chronic condition that originates as lipid accumulation within hepatocytes (steatosis) and progresses into nonalcoholic steatohepatitis (NASH), characterized by lipid accumulation, inflammation, oxidative stress, and fibrosis. NAFLD is now recognized as the most common cause of chronic liver disease, with a prevalence of 25% ...

ByOrganovo Holdings Inc.

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