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Biopsy Articles & Analysis

75 articles found

Immortalized Human Podocytes: A Breakthrough in Kidney Research

Immortalized Human Podocytes: A Breakthrough in Kidney Research

Unlike primary cell cultures that may require donor biopsies, immortalized cell lines can be generated from a single source while maintaining genetic diversity through the creation of multiple lines from different individuals. ...

ByCreative Bioarray


Understanding Circulating Tumor Cells (CTCs) and the Role of FISH

Understanding Circulating Tumor Cells (CTCs) and the Role of FISH

Moreover, the ability to study CTCs directly from a blood sample provides a less invasive approach compared to traditional tissue biopsies. This can be particularly beneficial for patients who may not be candidates for surgical biopsies due to their condition or for those whose tumors are difficult to access. ...

ByCreative Bioarray


Hydrogen and Methane Breath Testing in Children: A Practical Guide

Hydrogen and Methane Breath Testing in Children: A Practical Guide

Limitations of Alternative Tests for Lactose Intolerance Compared to HMBT: Another alternative way to test lactose intolerance is genetic testing (LCT gene), some clinicians may consider an LCT gene or intestinal biopsy for lactose intolerance. While genetic testing can be useful, particularly for identifying congenital lactase deficiency (CLD), it has limitations. Acquired ...

ByBedfont Scientific Limited


Understanding Colorectal Cancer Cell Lines: A Vital Tool in Cancer Research

Understanding Colorectal Cancer Cell Lines: A Vital Tool in Cancer Research

The establishment of cell lines involves extracting cancer cells from a tumor biopsy, followed by their growth in a nutrient-rich medium under sterile conditions. ...

ByCreative Bioarray


Speeding Up The Cancer Drug Discovery Process with Zebrafish Disease Models

Speeding Up The Cancer Drug Discovery Process with Zebrafish Disease Models

Tumor cells from primary or metastatic human cancers collected by surgery or biopsy procedures were transplanted into zebrafish. This approach provides information about the effectiveness of the treatment because the cells share the same molecular, genetic and clinical characteristics as the donor. ...

ByCreative Biogene


The Six Main Ingredients in Cell Culture Medium

The Six Main Ingredients in Cell Culture Medium

For such critical samples, especially those from diseased human biopsies, high-quality media are required. This reduces the risk of contamination and saves time, labor and money by eliminating required preparation steps and replenishment. ...

ByCreative Bioarray


Matched tumor-normal sequencing: The preferred method for identifying somatic mutations driving tumorigenesis

Matched tumor-normal sequencing: The preferred method for identifying somatic mutations driving tumorigenesis

Discover how matched tumor-normal sequencing can help clinical researchers detect the somatic origin of variants with certainty. In the era of precision oncology, it has become increasingly common for patients diagnosed with cancer to undergo tumor sequencing. Identifying the mutations that make up a tumor’s genomic landscape can help guide selection of targeted therapies and inform ...

BySOPHiA Genetics


Mastering Gut Health: Key Insights from Our Webinar on SIBO and Carbohydrate Malabsorption with Melissa Dooley.

Mastering Gut Health: Key Insights from Our Webinar on SIBO and Carbohydrate Malabsorption with Melissa Dooley.

Other test methods can include: · Endoscopic biopsies (invasive & costly) · Blood test (repeated every 30 minutes) · Stool acidity test (infants, young children) Home breath testing devices Home breath testing devices were more widely optimised due to the COVID-19 pandemic, to prevent waiting list delays and people felt safer taking ...

ByBedfont Scientific Limited


From Data to Decisions, Faster than Ever: Pioneering the future of precision medicine with the New Generation SOPHiA DDM Platform

From Data to Decisions, Faster than Ever: Pioneering the future of precision medicine with the New Generation SOPHiA DDM Platform

In response to the emerging needs in global healthcare, SOPHiA GENETICS has just revealed the New Generation SOPHiA DDM™ Platform, aiming to stay at the forefront of precision medicine and address today the healthcare needs of tomorrow. ...

BySOPHiA Genetics


Guidelines Spotlight: ESMO urge NGS testing for additional advanced cancers

Guidelines Spotlight: ESMO urge NGS testing for additional advanced cancers

ESMO updated its recommendations for NGS in advanced cancers this year, urging broader use of NGS in additional cancer types and the inclusion of tumor-agnostic biomarkers. The ESMO Precision Medicine Working Group (PMWG) first published its recommendations for when to use next-generation sequencing (NGS) in routine practice for patients with metastatic cancers in 20201. At that time, based ...

BySOPHiA Genetics


Q&A: The evolving role of antibody-drug conjugates in oncology

Q&A: The evolving role of antibody-drug conjugates in oncology

Dr. Kate Sasser from Tempus led a discussion on the potential of antibody-drug conjugates (ADCs), their challenges in targeting tumor antigens, and the future of cancer treatment with Dr. Daniel Johnson, Dr. Funda Meric-Bernstam, and Dr. Kellogg Parsons. The oncology field is rapidly advancing with the development of antibody-drug conjugates (ADCs), offering new hope for ...

ByTempus


Study of the pathogenic mechanisms of autoimmune myasthenia gravis - Case Study

Study of the pathogenic mechanisms of autoimmune myasthenia gravis - Case Study

Contexte Myasthenia gravis (MG) is an autoimmune disease caused by the presence of antibodies directed against components of the muscle membrane located at the neuromuscular junction. In the majority of cases, these are autoantibodies directed against the acetylcholine receptor (AChR). The origin of the autoimmune response is not known, but thymic abnormalities and defective regulation of the ...

ByInovarion


Case Study B - Liquid Biopsy

Case Study B - Liquid Biopsy

Project spearheaded by Singapore’s national Diagnostics Development (DxD) Hub Clinical trial introducing X-ZELL as an additional diagnostic tool Pilot study showed X-ZELL more than 70 per cent reduction in unnecessary biopsies ...

ByX-Zell Inc.


The Power of Digital Pathology: Why Labs Everywhere Should Make the Switch

The Power of Digital Pathology: Why Labs Everywhere Should Make the Switch

The literature shows that pathologists, being only humans under considerable pressure, may miss cancer in up to 1-3% of prostate biopsies.2,3,4 Considering the over one million men who are diagnosed worldwide per year, this may reflect a large number of patients.5 Moreover, the subjectivity of Gleason grading and tumor quantification can result in difficulty assigning effective ...

ByPaige AI, Inc.


Adenocarcinomas and Their Often Misleading Symptoms When Dyspepsia Is an Indication of Cancer - Case Study

Adenocarcinomas and Their Often Misleading Symptoms When Dyspepsia Is an Indication of Cancer - Case Study

Medical History Jane is a 40-year-old, married mother of two teenage boys. She teaches at the local elementary school and has been in good health for most of her life. She has no surgical history. Her most severe ailment up to this point has been the flu at age 27. Her students are first-graders; they are often difficult to control. She also experiences the normal stresses of raising ...

ByThe Medical Algorithms Company Limited


Tips & Tricks to Optimize Your Tissue Processing

Tips & Tricks to Optimize Your Tissue Processing

Since the 19th century, the practice of tissue processing has remained largely unchanged, resulting in solidified, paraffin-embedded tissue blocks for sectioning. As staining procedures have advanced and immunohistochemistry is becoming more widely used, high-quality tissue sections are paramount for accurate interpretation of disease ...

ByQuartzy Inc.


VLE for Post-Treatment Assessment - Case Study

VLE for Post-Treatment Assessment - Case Study

(Figures 1-3) Pathology of the EMR sample was positive for Adenocarcinoma (Figure 4) A subsequent surveillance ECD showed the previous EMR site, a normal GEJ. and normal distal esophageal lining. Random biopsies were taken of the treated area and were negative for dysplasia. ...

ByNinePoint Medical, Inc. (NPM)


VLE for Identification of Subsquamous Disease - Case Study

VLE for Identification of Subsquamous Disease - Case Study

At the referring center, previous resection of nodularity revealed Tla adenocarcinoma with negative margins. Subsequent surveillance biopsies yielded IMC, and triggered referral. For the procedures described here, standard endoscopy with the addition of Volumetric Laser Endomicroscopy (VLE). using the NvisionVLE; Imaging System with Real-time Targeting, was performed to localize ...

ByNinePoint Medical, Inc. (NPM)


Decreasing Benign Breast Ultrasound Biopsies: Prospective Use of AI Decision Support

Decreasing Benign Breast Ultrasound Biopsies: Prospective Use of AI Decision Support

After implementation of AI decision support, the benign biopsy rate decreased from 71.79% to 59.2% while the overall biopsy rate stayed constant. ...

ByKoios Medical, Inc.


An independent assessment of AI for prostate cancer detection - Case Study

An independent assessment of AI for prostate cancer detection - Case Study

Yale Medicine, an academic medical center with a high volume of prostate biopsies, conducted a study to determine Paige Prostate’s utility as a prescreening tool for clinical use. A total of 1,876 prostate core biopsy slides were analyzed by Paige Prostate, and only those cores categorized by the AI as “suspicious” or as out of distribution were ...

ByPaige AI, Inc.

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