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Blood Mononuclear Articles & Analysis

6 articles found

Going beneath the surface of skin cancer - Case study

Going beneath the surface of skin cancer - Case study

Findings were then validated in cryopreserved peripheral blood mononuclear cell samples from the same study, as well as an independent CyTOF dataset from a published metastatic melanoma trial. ...

ByOzette Technologies


HPV-16 E7-Specific Cellular Immune Response

HPV-16 E7-Specific Cellular Immune Response

In the current cross-sectional and longitudinal clinical study, we found that the HPV16 E7-specific T cell response in peripheral blood mononuclear cells of HPV16-infected patients is related to HPV16 clearance. ...

ByOxford Vacmedix UK Limited


Lactobacillus paracasei KBL382 administration attenuates atopic dermatitis by modulating immune response and gut microbiota

Lactobacillus paracasei KBL382 administration attenuates atopic dermatitis by modulating immune response and gut microbiota

Based on decreases in levels of Th1, Th2, and Th17-type cytokines and an increase in the anti-inflammatory cytokine IL-10 in peripheral blood mononuclear cells in vitro,46 we selected KBL382 for our AD-like experiment. ...

ByKoBioLabs


New Cell Contenders in the CAR Field (Part 1)

New Cell Contenders in the CAR Field (Part 1)

Chimeric antigen receptor T-cells (CAR-T) are one of the first clinically approved therapies to take full advantage of the most significant advancements in immunology and genetic engineering. The resulting therapeutics have been shown to produce remission rates exceeding 80% in patients with CD19+ B-cell lymphoma, making them nothing short of remarkable [1]. Unfortunately, CAR-T cells seem ...

ByIndee Labs


The response of peripheral blood mononuclear cells to shape memory alloys

The response of peripheral blood mononuclear cells to shape memory alloys

The aim of this work was to study the response of human peripheral blood mononuclear cells (PB-MNCs) to Cu-Al-Ni and Ni-Ti shape memory alloys (SMAs). ...

ByInderscience Publishers


Genetic modification of primary natural killer cells overcomes inhibitory signals and induces specific killing of leukemic cells

Genetic modification of primary natural killer cells overcomes inhibitory signals and induces specific killing of leukemic cells

An abundance of NK cells for transduction was secured by culturing peripheral blood mononuclear cells with K562 cells expressing the NK-stimulatory molecules 4-1BB ligand and interleukin 15, which yielded a median greater than 1000-fold expansion of CD56+CD3- cells at 3 weeks of culture, without T-lymphocyte expansion. ...

ByNkarta, Inc.

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