Cancer Genetic Articles & Analysis
46 articles found
These nanoparticles mimic the structure of viruses but lack the viral genetic material that makes viruses infectious. This unique characteristic offers a versatile platform for various innovative applications without the associated risks of viral infections. ...
This method is particularly useful in identifying genetic abnormalities associated with cancer, such as gene amplifications, deletions, and translocations, which can play a critical role in the diagnosis and treatment planning of cancer patients. ...
In the ever-evolving landscape of cancer research, two intriguing concepts have emerged that are reshaping how scientists approach treatment: synthetic lethality and parthanatos. Both concepts encapsulate the complexity of cellular processes and open new avenues for targeted therapies. What is Synthetic Lethality? Synthetic lethality occurs when the simultaneous disruption of two genes ...
Understanding the immune system is fundamental to advancing biomedical research, especially in areas such as cancer, autoimmune diseases, and infectious diseases. Mouse models play a pivotal role in this field, as their immune system shares many similarities with that of humans. A key aspect of studying the immune system involves analyzing cytokines, chemokines, and growth ...
The most commonly used colorectal cancer cell lines include HCT116, SW480, and HT-29, each with distinct genetic and phenotypic characteristics. ...
This approach has opened new avenues for immunotherapy, providing hope for treating conditions like cancer, autoimmune disorders, and genetic diseases. Understanding Primary T Cells Primary T cells play a vital role in the body’s defense mechanism. ...
The ability to deliver mRNA effectively to target cells is crucial for harnessing its potential in treating a variety of diseases, including infectious diseases, cancer, and genetic disorders. This article explores the latest advancements in mRNA delivery systems and their implications for future therapeutic applications. ...
In recent years, adeno-associated virus (AAV) particles have emerged as a pivotal tool in the realm of gene therapy, offering researchers and clinicians innovative approaches to treat a variety of genetic disorders. Premade AAV particles represent a significant advancement in this field, streamlining the process of gene delivery and significantly enhancing the efficiency and ...
Cancer is a worldwide disease and one of the leading causes of morbidity and mortality today. ...
It involves the delivery of new genetic molecules into target cells to treat diseases. This technology has the implicit to revise the treatment of inherited genetic disorders, cancer and other intractable driseases. ...
Discover how matched tumor-normal sequencing can help clinical researchers detect the somatic origin of variants with certainty. In the era of precision oncology, it has become increasingly common for patients diagnosed with cancer to undergo tumor sequencing. Identifying the mutations that make up a tumor’s genomic landscape can help guide selection of targeted therapies and inform ...
Some of the main functions of peptidomimetics include inhibiting or modulating enzymes & proteins, targeting specific receptors, and enhancing drug stability & bioavailability.Specifically, peptidomimetics can bind to enzymes and block their activity, making them useful in the development of cancer treatment. In addition, peptidomimetics can disrupt or potentiate ...
They are frequently employed in laboratory settings for applications such as the removal of RNA contaminants from DNA samples, thus enhancing the accuracy of genetic analyses. In RNA-sequencing (RNA-seq) protocols, RNases are used to fragment RNA, facilitating the generation of comprehensive RNA profiles for cellular studies. ...
Genomics: Whole-genome sequencing identifies genetic mutations and alterations driving tumor growth. This information is crucial for developing personalized therapies that target specific genetic abnormalities within the tumor. ...
It can also be used to study the mechanisms of some diseases, such as cancer, genetic diseases, and infectious diseases.1. Medical ResearchGene knockout is often used in medical research to study human diseases. ...
The exact cause of breast cancer is not completely understood, but factors such as genetics, hormone situations, and lifestyle choices can increase the threat of developing the disease. ...
Dr. Kate Sasser from Tempus led a discussion on the potential of antibody-drug conjugates (ADCs), their challenges in targeting tumor antigens, and the future of cancer treatment with Dr. Daniel Johnson, Dr. Funda Meric-Bernstam, and Dr. Kellogg Parsons. The oncology field is rapidly advancing with the development of antibody-drug conjugates (ADCs), offering new hope for ...
ByTempus
CDH1 acts as a tumor suppressor by inhibiting the Wnt/β-catenin pathway, which is often dysregulated in cancer. What is the role of CDH1 in cancer? The loss or dysfunction of CDH1 has been implicated in the development and progression of various types of cancer. ...
Antibody-drug conjugates, in particular, have gained significant attention in cancer therapy by combining the specificity of antibodies with the cytotoxicity of small molecules, enabling selective drug delivery to cancer cells while sparing healthy tissues. ...
Introduction Genomics has revolutionized cancer research, transforming the way we diagnose, treat, and monitor cancer. ...