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Cancer Screening Articles & Analysis
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This post-translational modification can activate or deactivate proteins, thus influencing various cellular processes such as growth, division, and apoptosis. The Importance of Kinase Screening Kinases are implicated in a myriad of diseases, particularly cancer, where their dysregulation leads to uncontrolled cell proliferation. Targeting specific kinases has ...
Colorectal cancer is one of the leading causes of cancer-related deaths globally. ...
Medical advancement relies on clinical trials, which are essential for the development of safe and effective innovative treatments. However, the success and general applicability of these treatments heavily depend on the diversity of the participants involved¹?³. This blog explores the importance of achieving data diversity in clinical trials to enhance clinical trial results and ...
Some of the main functions of peptidomimetics include inhibiting or modulating enzymes & proteins, targeting specific receptors, and enhancing drug stability & bioavailability.Specifically, peptidomimetics can bind to enzymes and block their activity, making them useful in the development of cancer treatment. In addition, peptidomimetics can disrupt or potentiate ...
Disease MechanismsStudy changes in oxidative phosphorylation in various diseases (such as neurodegenerative diseases, cancer).3. Drug Screening and Toxicity TestingEvaluate the impact of drugs on mitochondrial function.Precautions1. ...
ESMO updated its recommendations for NGS in advanced cancers this year, urging broader use of NGS in additional cancer types and the inclusion of tumor-agnostic biomarkers. The ESMO Precision Medicine Working Group (PMWG) first published its recommendations for when to use next-generation sequencing (NGS) in routine practice for patients with metastatic cancers in 20201. At that time, based ...
A glycan array is a high-throughput screening platform that allows researchers to study the interactions between glycans and other molecules, such as proteins, antibodies, and viruses. ...
Men seek treatment less frequently for a variety of medical conditions, largely due to a culture that encourages men to be stoic and deal with things themselves. Regular checkups and cancer screenings are more likely to be put off or skipped entirely by men. ...
INOVIQ (IIQ) signs a contract research agreement with Nicoya Lifesciences to develop a SubB2M-based test that uses its Alto digital surface plasmon resonance (SPR) platform The company believes a SubB2M-based SPR test has the potential to be developed as a multi-cancer detection test that first detects the Neu5Gc cancer signal Under the agreement, INOVIQ will pay an agreed cost for the work ...
As September and Blood Cancer Awareness Month wrap up, we want to reflect on a memorable conversation with Karen Thomas, a woman who received clonoSEQ® testing, and her physician, Dr. Hazma Hashmi, a hematologist-oncologist from the Medical University of South Carolina. At Adaptive, we know our diagnostic tests provide key information that help physicians and patients make treatment ...
The ClarityDX Prostate® test provides patients and physicians with an accurate prediction of clinically significant prostate cancer to support decision-making and improve health outcomes for men suspected of having prostate cancer. ...
Real-world data shows that at a 94% sensitivity level for prostate cancer ClarityDX Prostate® is 147% more specific than the PSA test for predicting clinically significant prostate cancer. ...
Data from 144 tissue samples in the feasibility study demonstrated that SubB2M immunohistochemistry detected melanoma with 91% sensitivity and discriminated between malignant melanoma and benign skin lesions. SubB2M-based immunohistochemistry applications represent a new product opportunity for SubB2M in the $1.9b immunohistochemistry market. INOVIQ Ltd (ASX:IIQ) has successfully completed ...
A preliminary 142-patient study with ClarityDX Bladder showed that it could accurately identify patients with bladder cancer compared to healthy individuals. “We are excited to launch our bladder cancer study and thank all the patients for their generous participation in the study” Tweet this Bladder cancer is the fifth most ...
The use of tumour markers to diagnose, assess prognosis, and select a suitable cancer treatment has become possible due to the development of inexpensive and user-friendly molecular analysis tools such as the polymerase chain reaction (PCR). Maintaining the integrity of biomarkers during their processing and storage is therefore of critical importance to accurately diagnose and give prognosis ...
In the study, the researchers propose a new method that mainly involves extensive screening of monoclonal antibodies against primary human tumor samples with the aim of identifying cancer-specific conformational epitopes throughout the protein that cannot be identified by transcriptome or proteome analysis. ...
Summary OTraces in collaboration with the Gertsen Institute in Moscow performed a blinded validation study on OTraces breast cancer detection products, the CDx Chemistry System for processing automated tests for detection of cancer; BC Sera Dx Immunochemistry test kit for the measurements of proteins that are predictive as a group of the presence on breast ...
For example, one study found that only 34.5% of Americans living in rural areas had access to a pulmonologist within 10 miles of their home, compared with 97.5% of those living in more urban areas.2 A similar study described the same lack of access to imaging services, finding that 77.8% of patients eligible for lung cancer screening had to drive more than 30 ...
Clinicians can make better diagnostic and treatment decisions using the data obtained by next-generation sequencing (NGS) technologies. Breast cancers, for example, have typically been diagnosed using mammography, physical exam, and histology. Genetics became more significant after the discoveries of oncogenes and other biomarkers. Today, commercially available microarray-based tests enable more ...
Studying the vaccine in dogs could provide insight into its effectiveness in people What if someone told you that a vaccine shot could prevent you from getting multiple types of cancer—ones as different from each other as breast cancer and lymphoma? Stephen A. Johnston, cofounder of the health-care start-up Calviri and a scientist at Arizona State University’s Biodesign Institute, ...
ByCalviri